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Abstract:

Nocardia globerula strain 432 was able to synthesize triacylglycerols (TAG) during cultivation on 2,6,10,14-tetramethyl pentadecane (pristane) under nitrogen-limiting conditions. Within these cells, 4,8,12-trimethyl tridecanoic acid was the major fatty acid detected. Fatty acids with an odd number of carbon atoms and minor amounts of even-numbered fatty acids were also observed. Experiments carried out with acrylic acid, an inhibitor of β-oxidation, suggested that odd-numbered fatty acids such as C15:0, C17:0 and 10-methyl C17:0 were synthesized de novo using propionyl-CoA, the β-oxidation product, as precursor. Although N. globerula 432 incorporated mainly straight chain fatty acids into TAG, the branched fatty acid 4,8,12-trimethyl tridecanoic acid also appeared, to some extent, in the acylglycerols. The importance of TAG biosynthesis by pristane-grown cells of N. globerula strain 432 is discussed. © 2001 Federation of European Microbiological Societies.

Registro:

Documento: Artículo
Título:Biosynthesis of fatty acids and triacylglycerols by 2,6,10,14-tetramethyl pentadecane-grown cells of Nocardia globerula 432
Autor:Alvarez, H.M.; Souto, M.F.; Viale, A.; Pucci, O.H.
Filiación:C.E.I.M.A., Facultad De Ciencias Naturales, Universidad Nacional De La Patagonia San Juan Bosco, Km 4, CC 1078, 9000 Comodoro Rivadavia, Chubut, Argentina
Departamento De Química Biológica, Facultad De Ciencias Exactas Y Naturales, Universidad Nacional De Buenos Aires, Buenos Aires, Argentina
Palabras clave:Fatty acid; Nocardia globerula; Pristane; Triacylglycerol; 2,6,10,14 tetramethyl pentadecane; 4,8,12 trimethyl tridecanoic acid; acrylic acid; alkane derivative; decanoic acid derivative; fatty acid derivative; propionyl coenzyme A; triacylglycerol; unclassified drug; Actinomyces; article; cell culture; controlled study; fatty acid oxidation; fatty acid synthesis; nocardia globerula; nonhuman; priority journal; Acetates; Acrylates; Carcinogens; Drug Interactions; Fatty Acids; Nocardia; Terpenes; Triglycerides
Año:2001
Volumen:200
Número:2
Página de inicio:195
Página de fin:200
DOI: http://dx.doi.org/10.1016/S0378-1097(01)00224-5
Título revista:FEMS Microbiology Letters
Título revista abreviado:FEMS Microbiol. Lett.
ISSN:03781097
CODEN:FMLED
CAS:Acetates; Acrylates; acrylic acid, 79-10-7; Carcinogens; Fatty Acids; pristane, 1921-70-6; Terpenes; Triglycerides
PDF:https://bibliotecadigital.exactas.uba.ar/download/paper/paper_03781097_v200_n2_p195_Alvarez.pdf
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03781097_v200_n2_p195_Alvarez

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Citas:

---------- APA ----------
Alvarez, H.M., Souto, M.F., Viale, A. & Pucci, O.H. (2001) . Biosynthesis of fatty acids and triacylglycerols by 2,6,10,14-tetramethyl pentadecane-grown cells of Nocardia globerula 432. FEMS Microbiology Letters, 200(2), 195-200.
http://dx.doi.org/10.1016/S0378-1097(01)00224-5
---------- CHICAGO ----------
Alvarez, H.M., Souto, M.F., Viale, A., Pucci, O.H. "Biosynthesis of fatty acids and triacylglycerols by 2,6,10,14-tetramethyl pentadecane-grown cells of Nocardia globerula 432" . FEMS Microbiology Letters 200, no. 2 (2001) : 195-200.
http://dx.doi.org/10.1016/S0378-1097(01)00224-5
---------- MLA ----------
Alvarez, H.M., Souto, M.F., Viale, A., Pucci, O.H. "Biosynthesis of fatty acids and triacylglycerols by 2,6,10,14-tetramethyl pentadecane-grown cells of Nocardia globerula 432" . FEMS Microbiology Letters, vol. 200, no. 2, 2001, pp. 195-200.
http://dx.doi.org/10.1016/S0378-1097(01)00224-5
---------- VANCOUVER ----------
Alvarez, H.M., Souto, M.F., Viale, A., Pucci, O.H. Biosynthesis of fatty acids and triacylglycerols by 2,6,10,14-tetramethyl pentadecane-grown cells of Nocardia globerula 432. FEMS Microbiol. Lett. 2001;200(2):195-200.
http://dx.doi.org/10.1016/S0378-1097(01)00224-5