Artículo
Montemartini, M.; Santomé, J.; Cazzulo, J.J.; Nowicki, C. "Production of aromatic α-hydroxyacids by epimastigotes of Trypanosoma cruzi, and its possible role in NADH reoxidation" (1994) FEMS Microbiology Letters. 118(1-2):89-92
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Abstract:
Epimastigotes of Trypanosoma cruzi in culture produce and excrete into the medium small amounts of phenyllactic acid and p-hydrocyphenyllactic acids, presumbly arising from the catabolism of the aromatic amino acids phenylalanine and tyrosine, respectively. This production might constitute a minor pathway for the reoxidation of cytosolic NADH, through the concerted action of tyrosine aminotransferase and aromatic α-hydroxyacid dehydrogenase. © 1994.
Registro:
| Documento: | Artículo |
| Título: | Production of aromatic α-hydroxyacids by epimastigotes of Trypanosoma cruzi, and its possible role in NADH reoxidation |
| Autor: | Montemartini, M.; Santomé, J.; Cazzulo, J.J.; Nowicki, C. |
| Filiación: | IQUIFIB (UBA-CONICET), Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junin 956, 1113 Buenos Aires, Argentina Instituto de Investigaciones Bioquímicas Luis F. Leloir, Fundación Campomar, CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, A. Machado 151, 1405 Buenos Aires, Argentina |
| Palabras clave: | Aromatic acids; Epimastigote; NADH reoxidation; Trypanosoma cruzi; aromatic alpha hydroxy acid; aromatic amino acid; reduced nicotinamide adenine dinucleotide; unclassified drug; article; epimastigote; nonhuman; oxidation; priority journal; trypanosoma cruzi; Animal; Hydroxy Acids; Indoles; Lactates; Models, Biological; NAD; Oxidation-Reduction; Oxidoreductases; Phenylpropionates; Support, Non-U.S. Gov't; Trypanosoma cruzi; Trypanosoma; Trypanosoma cruzi |
| Año: | 1994 |
| Volumen: | 118 |
| Número: | 1-2 |
| Página de inicio: | 89 |
| Página de fin: | 92 |
| Título revista: | FEMS Microbiology Letters |
| Título revista abreviado: | FEMS Microbiol. Lett. |
| ISSN: | 03781097 |
| CODEN: | FMLED |
| CAS: | 4-hydroxyphenyllactic acid, 306-23-0; Hydroxy Acids; indole-3-lactic acid, 1821-52-9; Indoles; Lactates; NAD, 53-84-9; Oxidoreductases, EC 1.; Phenylpropionates |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03781097_v118_n1-2_p89_Montemartini |
Referencias:
- Stibbs, Seed, Metabolism of tyrosine and phenylalanine in Trypanosoma brucei gambiense (1975) Int. J. Biochem., 6, pp. 197-203
- Stibbs, Seed, Further studies on the metabolism of tryptophan in Trypanosoma brucei gambiense: cofactors, inhibitors, and endproducts (1975) Experientia, 31, pp. 274-277
- Stibbs, Seed, Short-term metabolism of [14C] tryptophan in rats infected with Trypanosoma brucei gambiense (1975) J. Infect. Dis., 131, pp. 459-462
- Nowicki, Montemartini, Duschak, Santomé, Cazzulo, Presence and subcellular localization of tyrosine aminotransferase and p-hydroxyphenyl lactate dehydrogenase n epimastigotes of Trypanosoma cruzi (1992) FEMS Microbiol. Lett., 92, pp. 119-124
- Montemartini, Santomé, Cazzulo, Nowicki, Purification and partial structural and kinetic characterization of tyrosine aminotransferase from epimastigotes of Trypanosoma cruzi (1993) Biochem. J., 292, pp. 901-906
- Cazzulo, Franke de Cazzulo, Engel, Cannata, End products and enzyme levels of aerobic glucose fermentation in Trypanosomatids (1985) Mol. Biochem. Parasitol., 16, pp. 329-343
- Cazzulo, The aerobic fermentation of glucose by Trypanosomatids (1992) FASEB J., 6, pp. 3153-3161
- Engel, Frank de Cazzulo, Stoppani, Cannata, Cazzulo, Aerobic glucose fermentation by Trypanosoma cruzi axenic culture amastigote-like forms growth and diffentiation to epimastigotes (1987) Mol. Biochem. Parasitol., 26, pp. 1-10
Citas:
---------- APA ----------
Montemartini, M., Santomé, J., Cazzulo, J.J. & Nowicki, C. (1994) . Production of aromatic α-hydroxyacids by epimastigotes of Trypanosoma cruzi, and its possible role in NADH reoxidation. FEMS Microbiology Letters, 118(1-2), 89-92.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03781097_v118_n1-2_p89_Montemartini [ ]
---------- CHICAGO ----------
Montemartini, M., Santomé, J., Cazzulo, J.J., Nowicki, C. "Production of aromatic α-hydroxyacids by epimastigotes of Trypanosoma cruzi, and its possible role in NADH reoxidation" . FEMS Microbiology Letters 118, no. 1-2 (1994) : 89-92.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03781097_v118_n1-2_p89_Montemartini [ ]
---------- MLA ----------
Montemartini, M., Santomé, J., Cazzulo, J.J., Nowicki, C. "Production of aromatic α-hydroxyacids by epimastigotes of Trypanosoma cruzi, and its possible role in NADH reoxidation" . FEMS Microbiology Letters, vol. 118, no. 1-2, 1994, pp. 89-92.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03781097_v118_n1-2_p89_Montemartini [ ]
---------- VANCOUVER ----------
Montemartini, M., Santomé, J., Cazzulo, J.J., Nowicki, C. Production of aromatic α-hydroxyacids by epimastigotes of Trypanosoma cruzi, and its possible role in NADH reoxidation. FEMS Microbiol. Lett. 1994;118(1-2):89-92.Available from: https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03781097_v118_n1-2_p89_Montemartini [ ]
