Artículo
Sintas, J.A.; Macareno, N.J.; Vitale, A.A. "Synthesis of 8-[10B]-dihydroxyboryl-harmine, a potential agent for boron neutron capture therapy" (2000) Journal of Labelled Compounds and Radiopharmaceuticals. 43(1):97-101
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Abstract:
The preparation and spectral properties (MS, IR and NMR) of 8-[10B]-dihydroxyborylharmine (III) are described. A general synthetic method was developed for an efficient production of boronated harmine; a potential agent for boron neutron capture therapy (BNCT) in brain.
Registro:
| Documento: | Artículo |
| Título: | Synthesis of 8-[10B]-dihydroxyboryl-harmine, a potential agent for boron neutron capture therapy |
| Autor: | Sintas, J.A.; Macareno, N.J.; Vitale, A.A. |
| Filiación: | PROPLAME-CONICET, Depto. de Quim. Orgánica, Universidad de Buenos Aires, Pabellón 2, 1428 Buenos Aires, Argentina |
| Palabras clave: | 8-[10B]-dihydroxyborylharmine; Boron neutron capture therapy; Preparation and characterization; harmine; radiopharmaceutical agent; article; infrared spectrometry; mass spectrometry; neutron capture therapy; nuclear magnetic resonance spectroscopy |
| Año: | 2000 |
| Volumen: | 43 |
| Número: | 1 |
| Página de inicio: | 97 |
| Página de fin: | 101 |
| DOI: | http://dx.doi.org/10.1002/(SICI)1099-1344(200001)43:1<97::AID-JLCR296>3.0.CO;2-D |
| Título revista: | Journal of Labelled Compounds and Radiopharmaceuticals |
| Título revista abreviado: | J. Label. Compd. Radiopharm. |
| ISSN: | 03624803 |
| CODEN: | JLCRD |
| CAS: | harmine, 343-27-1, 442-51-3 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03624803_v43_n1_p97_Sintas |
Referencias:
- Morin, C., (1994) Tetrahedron, 50, pp. 12521-12569
- Pawlik, M., Kaulen, P., Baumgarten, H.G., Rommelspacher, H., (1990) Journal of Neuroanathomy, 3, pp. 19-25
- Sintas, J.A., Vitale, A.A., (1997) J. Lab Comp. Radioparm., 39, pp. 677-684
- Sintas, J.A., Vitale, A.A., (1998) J. Lab Comp. Radioparm., 41, pp. 53-61
- Sintas, J.A., Vitale, A.A., (1999) J. Lab Comp. Radioparm., 42, pp. 409-413
- Koehler, K.A., Hess, G.P., (1974) Biochemistry, 13, pp. 5345-5350
- Shlesinguer, H.I., Browz, H.C., Mayfield, D.L., (1953) J. Amer. Chem. Soc., 71, pp. 213-215
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Citas:
---------- APA ----------
Sintas, J.A., Macareno, N.J. & Vitale, A.A. (2000) . Synthesis of 8-[10B]-dihydroxyboryl-harmine, a potential agent for boron neutron capture therapy. Journal of Labelled Compounds and Radiopharmaceuticals, 43(1), 97-101.http://dx.doi.org/10.1002/(SICI)1099-1344(200001)43:1<97::AID-JLCR296>3.0.CO;2-D
---------- CHICAGO ----------
Sintas, J.A., Macareno, N.J., Vitale, A.A. "Synthesis of 8-[10B]-dihydroxyboryl-harmine, a potential agent for boron neutron capture therapy" . Journal of Labelled Compounds and Radiopharmaceuticals 43, no. 1 (2000) : 97-101.http://dx.doi.org/10.1002/(SICI)1099-1344(200001)43:1<97::AID-JLCR296>3.0.CO;2-D
---------- MLA ----------
Sintas, J.A., Macareno, N.J., Vitale, A.A. "Synthesis of 8-[10B]-dihydroxyboryl-harmine, a potential agent for boron neutron capture therapy" . Journal of Labelled Compounds and Radiopharmaceuticals, vol. 43, no. 1, 2000, pp. 97-101.http://dx.doi.org/10.1002/(SICI)1099-1344(200001)43:1<97::AID-JLCR296>3.0.CO;2-D
---------- VANCOUVER ----------
Sintas, J.A., Macareno, N.J., Vitale, A.A. Synthesis of 8-[10B]-dihydroxyboryl-harmine, a potential agent for boron neutron capture therapy. J. Label. Compd. Radiopharm. 2000;43(1):97-101.http://dx.doi.org/10.1002/(SICI)1099-1344(200001)43:1<97::AID-JLCR296>3.0.CO;2-D
