The chemical nature of cellular structures involved in the attachment of Junin virus (wild type XJC13 and host range mutant Cl 67) to Vero cells was investigated. Enzyme treatment of cells before virus infection indicated that whereas lipids are not directly involved in virus attachment, cellular proteins play a significant role in early interaction with JV. Moreover aromatic residues, leucine and basic amino acid seem to actively participate in this interaction with different affinity for the assayed strains.
Documento: | Artículo |
Título: | Influence] of enzymatic treatment on Junin virus--Vero cells interaction |
Autor: | Raiger Iustman, L.J.; Candurra, N.; Mersich, S.E. |
Filiación: | Depto. de Química Biológica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina |
Palabras clave: | enzyme; animal; article; cell culture; Cercopithecus; drug effect; female; Junin virus; male; physiology; Vero cell; virology; Animals; Cells, Cultured; Cercopithecus aethiops; Enzymes; Female; Junin virus; Male; Vero Cells |
Año: | 1995 |
Volumen: | 27 |
Número: | 1 |
Página de inicio: | 28 |
Página de fin: | 32 |
Título revista: | Revista Argentina de microbiología |
Título revista abreviado: | Rev. Argent. Microbiol. |
ISSN: | 03257541 |
CAS: | Enzymes |
Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03257541_v27_n1_p28_RaigerIustman |