Addition of 0.3% (w/w) of potassium sorbate (a permitted food additive) coupled with a reduction of pH from 7 to 6 or 5.5, resulted in a dramatic decrease in the survival of two S. aureus strains inoculated (10(8) c.f.u./ml) in laboratory media supplemented with sugar (227 g sugar/100 g water) and incubated at 35 degrees C. These in vitro results may be of potential value to improve the efficacy of sugar therapy for the treatment of certain infected wounds; however, clinical trials are needed to confirm these findings.
Documento: | Artículo |
Título: | Effect of potassium sorbate and pH on the survival of Staphylococcus aureus in saturated sugar solutions. |
Autor: | Chirife, J.; Herszage, L.; Joseph, A.; Kohn, E.S. |
Filiación: | Departamento de Industrias, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina |
Palabras clave: | food additive; hypertonic solution; sorbic acid; sucrose; article; comparative study; drug effect; growth, development and aging; osmolarity; pH; Staphylococcus aureus; Food Additives; Hydrogen-Ion Concentration; Hypertonic Solutions; Osmolar Concentration; Sorbic Acid; Staphylococcus aureus; Sucrose |
Año: | 1993 |
Volumen: | 25 |
Número: | 2 |
Página de inicio: | 80 |
Página de fin: | 87 |
Título revista: | Revista Argentina de microbiología |
Título revista abreviado: | Rev. Argent. Microbiol. |
ISSN: | 03257541 |
CAS: | sorbic acid, 110-44-1, 22500-92-1; sucrose, 122880-25-5, 57-50-1; Food Additives; Hypertonic Solutions; Sorbic Acid, 110-44-1; Sucrose, 57-50-1 |
Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03257541_v25_n2_p80_Chirife |