Artículo
Abstract:
The importance of synthetic organic pesticides will continue to increase as the world population grows relative to a fairly constant amount of arable land. Pesticides save 10 % of the crops, but an additional 37 % is still lost to pests. Insecticides are used here to illustrate the needs and prospects for safer and more effective agrochemicals. The major insecticides (88 % based on sales) act at four nerve targets: acetylcholinesterase (62 %), the voltage-dependent sodium channel (18 %), the gamma-aminobutyric acid-gated chloride ion channel ( 6 %), and the nicotic acetylcholine receptor (2 %). The utility of the first three of these targets will be increasingly compromised by insect resistance problems while the nicotinic acetylcholine receptor is projected to grow in significance. Compounds that act at non-nerve targets will also become more important. They include uncouplers of oxidative phosphorylation, inhibitors of NADH/ubiquinone oxidoreductase and of ATPase, growth regulators (juvenoids and ecdysone agonists), and microbial pesticides acting at a variety of sites. With about 300 commercial insecticides and with only two to five new compounds likely to be introduced per year on the average, it is essential to make the most effective use of the current insecticides. The newer chemicals are often more complex and more expensive compared to earlier insecticides, but they are used at much lower rates thereby making them cost effective and minimizing the environmental burden. They are also ideally active against resistant strains, compatible with integrated pest management programs, and possess minimal mammalian toxicity.
Registro:
| Documento: | Artículo |
| Título: | Los insecticidas actuales y las perspectivas de los nuevos para el futuro |
| Autor: | Wood, E.J. |
| Filiación: | CIPEIN (CITEFA-CONICET), Catedra de Toxicol. y Quim. Leg., FCEN-UBA (CIPEIN) CITEFA, Zufriategui 4380, (1603) Villa Martelli, Argentina |
| Idioma: | Español |
| Palabras clave: | Acetylcholine receptor; Acetylcholinesterase; Chloride channel; Ecotoxicology; Insecticide; New biochemical targets; Resistance; Respiration inhibitors; Sodium channel; Toxicology |
| Año: | 1996 |
| Volumen: | 30 |
| Número: | 4 |
| Página de inicio: | 357 |
| Página de fin: | 369 |
| Título revista: | Acta Bioquimica Clinica Latinoamericana |
| Título revista abreviado: | Acta Bioquim. Clin. Latinoam. |
| ISSN: | 03252957 |
| CODEN: | ABCLD |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03252957_v30_n4_p357_Wood |
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Citas:
---------- APA ----------
(1996) . Los insecticidas actuales y las perspectivas de los nuevos para el futuro. Acta Bioquimica Clinica Latinoamericana, 30(4), 357-369.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03252957_v30_n4_p357_Wood [ ]
---------- CHICAGO ----------
Wood, E.J. "Los insecticidas actuales y las perspectivas de los nuevos para el futuro" . Acta Bioquimica Clinica Latinoamericana 30, no. 4 (1996) : 357-369.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03252957_v30_n4_p357_Wood [ ]
---------- MLA ----------
Wood, E.J. "Los insecticidas actuales y las perspectivas de los nuevos para el futuro" . Acta Bioquimica Clinica Latinoamericana, vol. 30, no. 4, 1996, pp. 357-369.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03252957_v30_n4_p357_Wood [ ]
---------- VANCOUVER ----------
Wood, E.J. Los insecticidas actuales y las perspectivas de los nuevos para el futuro. Acta Bioquim. Clin. Latinoam. 1996;30(4):357-369.Available from: https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03252957_v30_n4_p357_Wood [ ]
