Artículo
Romero, C.; Alvarez, M.G.; Storino, O.; Taratuto, A.L.; Alfonso, J.M.; Massaro, M.; Meli, F. "Leigh syndrome. Differential diagnosis in brainstem lesions " (2004) Revista Neurologica Argentina. 29(3):166-168
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Abstract:
We report the case of a 4 year-old-girl with a late infatile onset encephalopathy and first metabolic crisis at the age of 16 months resulting in pyramidal and extrapyramidal involvement associated with severe axial hypotonia.Later she developed ocular movement and sleep abnormalities and recurrent intestinal pseudo-occlusive epidoses. Metabolic workup was normal in blood and urine, with high lactate on CSF. Muscle histopathologic and histochemical revealed normal structure with evidences of increased oxidative mitocondrial activity. MRI showed symmetrical and bilateral brain stem lesions with low signal in T1 and high signal in T2 and difusion-weighted images. The clinical evolution and radiological abnormalities are consistent with the infantile form of Leigh Syndrome.
Registro:
| Documento: | Artículo |
| Título: | Leigh syndrome. Differential diagnosis in brainstem lesions |
| Autor: | Romero, C.; Alvarez, M.G.; Storino, O.; Taratuto, A.L.; Alfonso, J.M.; Massaro, M.; Meli, F. |
| Filiación: | Servicio de Resonancia Magnética, F.L.E.N.I Instituto de Investigaciones Neurológicas Raúl Carrea Servicio de Neuropediatría, F.L.E.N.I Instituto de Investigaciones Neurológicas Raúl Carrea Servicio de Anestesología, F.L.E.N.I Instituto de Investigaciones Neurológicas Raúl Carrea Servicio de Neuropatología, F.L.E.N.I Instituto de Investigaciones Neurológicas Raúl Carrea Montañeses 2325, 1428 Buenos Aires, Argentina |
| Palabras clave: | Respiratory chain diseases-mtDNA mutation-Brain MRI |
| Año: | 2004 |
| Volumen: | 29 |
| Número: | 3 |
| Página de inicio: | 166 |
| Página de fin: | 168 |
| Título revista: | Revista Neurologica Argentina |
| Título revista abreviado: | Rev. Neurol. Argent. |
| ISSN: | 03250938 |
| CODEN: | RNARD |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03250938_v29_n3_p166_Romero |
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Citas:
---------- APA ----------
Romero, C., Alvarez, M.G., Storino, O., Taratuto, A.L., Alfonso, J.M., Massaro, M. & Meli, F. (2004) . Leigh syndrome. Differential diagnosis in brainstem lesions . Revista Neurologica Argentina, 29(3), 166-168.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03250938_v29_n3_p166_Romero [ ]
---------- CHICAGO ----------
Romero, C., Alvarez, M.G., Storino, O., Taratuto, A.L., Alfonso, J.M., Massaro, M., et al. "Leigh syndrome. Differential diagnosis in brainstem lesions " . Revista Neurologica Argentina 29, no. 3 (2004) : 166-168.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03250938_v29_n3_p166_Romero [ ]
---------- MLA ----------
Romero, C., Alvarez, M.G., Storino, O., Taratuto, A.L., Alfonso, J.M., Massaro, M., et al. "Leigh syndrome. Differential diagnosis in brainstem lesions " . Revista Neurologica Argentina, vol. 29, no. 3, 2004, pp. 166-168.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03250938_v29_n3_p166_Romero [ ]
---------- VANCOUVER ----------
Romero, C., Alvarez, M.G., Storino, O., Taratuto, A.L., Alfonso, J.M., Massaro, M., et al. Leigh syndrome. Differential diagnosis in brainstem lesions . Rev. Neurol. Argent. 2004;29(3):166-168.Available from: https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03250938_v29_n3_p166_Romero [ ]
