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Abstract:

Hereditary spherocytosis must always be suspected in children with anemia, hyperbilirubinemia, splenomegaly or cholelithiasis, in the asymptomatic individual with an affected relative, and in the neonate with hyperbilirubinemia with no blood group incompatibility; its early detection is key to avoid kernicterus. Follow-up of these patients is based on periodical control and supply of information on the adequate management of hemolytic or aplastic crisis, and early detection of cholelithiasis. The decision to perform splenectomy is usually associated with quality of life rather than life-threatening risk, and it should result from a consensus between patient, parents and physicians. The postsplenectomy follow-up is based on control of compliance with the prophylactic antibiotic therapy and the early diagnosis of infectious disorders. © 2015, Sociedad Argentina de Pediatria. All rights reserved.

Registro:

Documento: Artículo
Título:Hereditary Spherocytosis. Review. Part II. Symptomatology, outcome, complications, and treatment
Autor:Donato, H.; Crisp, R.L.; Rapetti, M.C.; García, E.; Attie, M.
Filiación:Hospital del Niño de San Justo, Sección Hematología/Oncología, Argentina
Hospital Nacional Prof. A. Posadas, División Hematología Clínica, Argentina
Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Departamento de Química Biológica, Argentina
Hospital de Niños Ricardo Gutiérrez, Servicio de Hematología, Argentina
Palabras clave:Cholelithiasis; Hemolytic anemia; Hereditary spherocytosis; Hyperbilirubinemia; Splenectomy; antibiotic therapy; aplastic crisis; cholelithiasis; early diagnosis; follow up; hereditary spherocytosis; human; outcome assessment; prophylaxis; quality of life; Review; splenectomy; symptomatology; adolescent; child; complication; preschool child; Spherocytosis, Hereditary; treatment outcome; Adolescent; Child; Child, Preschool; Humans; Spherocytosis, Hereditary; Splenectomy; Treatment Outcome
Año:2015
Volumen:113
Número:2
Página de inicio:168
Página de fin:176
DOI: http://dx.doi.org/10.5546/aap.2015.168
Título revista:Archivos Argentinos de Pediatria
Título revista abreviado:Arch. Argent. Pediatr.
ISSN:03250075
CODEN:AHAPA
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03250075_v113_n2_p168_Donato

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Citas:

---------- APA ----------
Donato, H., Crisp, R.L., Rapetti, M.C., García, E. & Attie, M. (2015) . Hereditary Spherocytosis. Review. Part II. Symptomatology, outcome, complications, and treatment . Archivos Argentinos de Pediatria, 113(2), 168-176.
http://dx.doi.org/10.5546/aap.2015.168
---------- CHICAGO ----------
Donato, H., Crisp, R.L., Rapetti, M.C., García, E., Attie, M. "Hereditary Spherocytosis. Review. Part II. Symptomatology, outcome, complications, and treatment " . Archivos Argentinos de Pediatria 113, no. 2 (2015) : 168-176.
http://dx.doi.org/10.5546/aap.2015.168
---------- MLA ----------
Donato, H., Crisp, R.L., Rapetti, M.C., García, E., Attie, M. "Hereditary Spherocytosis. Review. Part II. Symptomatology, outcome, complications, and treatment " . Archivos Argentinos de Pediatria, vol. 113, no. 2, 2015, pp. 168-176.
http://dx.doi.org/10.5546/aap.2015.168
---------- VANCOUVER ----------
Donato, H., Crisp, R.L., Rapetti, M.C., García, E., Attie, M. Hereditary Spherocytosis. Review. Part II. Symptomatology, outcome, complications, and treatment . Arch. Argent. Pediatr. 2015;113(2):168-176.
http://dx.doi.org/10.5546/aap.2015.168