Abstract:
Incubation of Candida albicans yeast cells with human luteinizing hormone (hLH), human chorionic gonadotrophin (hCG) or glucagon produced a significant rise in cAMP total levels. The effect of these hormones in permeabilized cells of the fungus produced a 2-3 fold increase in the Mg2+, GTP-dependent adenylyl cyclase activity as well as full activation of the cAMP-dependent protein kinase (PKA) activity. These results indicate that the interaction of the mammalian hormones with the fungus triggered the cAMP activation cascade in a similar way to that found in higher eukaryotic organisms. © 1991.
Registro:
Documento: |
Artículo
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Título: | Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans |
Autor: | Paveto, C.; Mallo, G.; Egidy, G.; Galvagno, M.A.; Passeron, S. |
Filiación: | Departamento de Química Biológica, Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas y Naturales, Pabellón II, 1428 Buenos Aires, Argentina
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Palabras clave: | adenylate cyclase; chorionic gonadotropin; cyclic amp; glucagon; luteinizing hormone; article; candida albicans; nonhuman; priority journal; steroidogenesis; Adenylate Cyclase; Candida albicans; Cell Membrane Permeability; Chorionic Gonadotropin; Cyclic AMP; Glucagon; Human; Luteinizing Hormone; Magnesium; Protein Kinases; Second Messenger Systems; Support, Non-U.S. Gov't; Toluene |
Año: | 1991
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Volumen: | 15
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Número: | 2
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Página de inicio: | 169
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Página de fin: | 178
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DOI: |
http://dx.doi.org/10.1016/0309-1651(91)90108-U |
Título revista: | Cell Biology International Reports
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Título revista abreviado: | Cell Biol. Int. Rep.
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ISSN: | 03091651
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CODEN: | CBRPD
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CAS: | Adenylate Cyclase, EC 4.6.1.1; Chorionic Gonadotropin; Cyclic AMP, 60-92-4; Glucagon, 9007-92-5; Luteinizing Hormone, 9002-67-9; Magnesium, 7439-95-4; Protein Kinases, EC 2.7.1.37; Toluene, 108-88-3
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03091651_v15_n2_p169_Paveto |
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Citas:
---------- APA ----------
Paveto, C., Mallo, G., Egidy, G., Galvagno, M.A. & Passeron, S.
(1991)
. Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans. Cell Biology International Reports, 15(2), 169-178.
http://dx.doi.org/10.1016/0309-1651(91)90108-U---------- CHICAGO ----------
Paveto, C., Mallo, G., Egidy, G., Galvagno, M.A., Passeron, S.
"Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans"
. Cell Biology International Reports 15, no. 2
(1991) : 169-178.
http://dx.doi.org/10.1016/0309-1651(91)90108-U---------- MLA ----------
Paveto, C., Mallo, G., Egidy, G., Galvagno, M.A., Passeron, S.
"Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans"
. Cell Biology International Reports, vol. 15, no. 2, 1991, pp. 169-178.
http://dx.doi.org/10.1016/0309-1651(91)90108-U---------- VANCOUVER ----------
Paveto, C., Mallo, G., Egidy, G., Galvagno, M.A., Passeron, S. Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans. Cell Biol. Int. Rep. 1991;15(2):169-178.
http://dx.doi.org/10.1016/0309-1651(91)90108-U