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Abstract:

Incubation of Candida albicans yeast cells with human luteinizing hormone (hLH), human chorionic gonadotrophin (hCG) or glucagon produced a significant rise in cAMP total levels. The effect of these hormones in permeabilized cells of the fungus produced a 2-3 fold increase in the Mg2+, GTP-dependent adenylyl cyclase activity as well as full activation of the cAMP-dependent protein kinase (PKA) activity. These results indicate that the interaction of the mammalian hormones with the fungus triggered the cAMP activation cascade in a similar way to that found in higher eukaryotic organisms. © 1991.

Registro:

Documento: Artículo
Título:Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans
Autor:Paveto, C.; Mallo, G.; Egidy, G.; Galvagno, M.A.; Passeron, S.
Filiación:Departamento de Química Biológica, Departamento de Ciencias Biológicas, Facultad de Ciencias Exactas y Naturales, Pabellón II, 1428 Buenos Aires, Argentina
Palabras clave:adenylate cyclase; chorionic gonadotropin; cyclic amp; glucagon; luteinizing hormone; article; candida albicans; nonhuman; priority journal; steroidogenesis; Adenylate Cyclase; Candida albicans; Cell Membrane Permeability; Chorionic Gonadotropin; Cyclic AMP; Glucagon; Human; Luteinizing Hormone; Magnesium; Protein Kinases; Second Messenger Systems; Support, Non-U.S. Gov't; Toluene
Año:1991
Volumen:15
Número:2
Página de inicio:169
Página de fin:178
DOI: http://dx.doi.org/10.1016/0309-1651(91)90108-U
Título revista:Cell Biology International Reports
Título revista abreviado:Cell Biol. Int. Rep.
ISSN:03091651
CODEN:CBRPD
CAS:Adenylate Cyclase, EC 4.6.1.1; Chorionic Gonadotropin; Cyclic AMP, 60-92-4; Glucagon, 9007-92-5; Luteinizing Hormone, 9002-67-9; Magnesium, 7439-95-4; Protein Kinases, EC 2.7.1.37; Toluene, 108-88-3
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03091651_v15_n2_p169_Paveto

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Citas:

---------- APA ----------
Paveto, C., Mallo, G., Egidy, G., Galvagno, M.A. & Passeron, S. (1991) . Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans. Cell Biology International Reports, 15(2), 169-178.
http://dx.doi.org/10.1016/0309-1651(91)90108-U
---------- CHICAGO ----------
Paveto, C., Mallo, G., Egidy, G., Galvagno, M.A., Passeron, S. "Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans" . Cell Biology International Reports 15, no. 2 (1991) : 169-178.
http://dx.doi.org/10.1016/0309-1651(91)90108-U
---------- MLA ----------
Paveto, C., Mallo, G., Egidy, G., Galvagno, M.A., Passeron, S. "Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans" . Cell Biology International Reports, vol. 15, no. 2, 1991, pp. 169-178.
http://dx.doi.org/10.1016/0309-1651(91)90108-U
---------- VANCOUVER ----------
Paveto, C., Mallo, G., Egidy, G., Galvagno, M.A., Passeron, S. Activation of the cAMP cascade by steroidogenic hormones and glucagon in the pathogenic fungus Candida albicans. Cell Biol. Int. Rep. 1991;15(2):169-178.
http://dx.doi.org/10.1016/0309-1651(91)90108-U