Artículo
Cicardo, V.H.; Carneiro de Rondina, D.; Mastronardi, I.O. "Brain monoamine content in rats treated with the antidepressants mianserin and amoxapine" (1983) IRCS Medical Science. 11(9):838
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Abstract:
In male Wistar rats intraperitoneal injection (21 days) of mianserin, a tetracyclic antidepressant (10 mg/kg), produced significant dimunition (p < 0.01) of brain noradrenaline content without any changes in dopamine or serotonin content. Amoxapine, a tricyclic antidepressant with a potent inhibitory action of catecholamine presynaptic uptake (10 mg/kg i.p.), did not produce any changes in brain monoamine content. During the experiments the rats treated with mianserin were more quiet than the controls and remained crowded together.
Registro:
| Documento: | Artículo |
| Título: | Brain monoamine content in rats treated with the antidepressants mianserin and amoxapine |
| Autor: | Cicardo, V.H.; Carneiro de Rondina, D.; Mastronardi, I.O. |
| Filiación: | Centro de Investigaciones Farmacologicas y de Principios Naturales, Buenos Aires, Argentina |
| Palabras clave: | amoxapine; brain monoamine; dopamine; mianserin; noradrenalin; serotonin; animal experiment; autonomic nervous system; biological model; central nervous system; drug comparison; drug efficacy; intraperitoneal drug administration; methodology; nonhuman; rat; Animalia; Rattus norvegicus |
| Año: | 1983 |
| Volumen: | 11 |
| Número: | 9 |
| Página de inicio: | 838 |
| Título revista: | IRCS Medical Science |
| Título revista abreviado: | IRCS MED. SCI. |
| ISSN: | 03056651 |
| CODEN: | IRLCD |
| CAS: | amoxapine, 14028-44-5; dopamine, 51-61-6, 62-31-7; mianserin, 21535-47-7, 24219-97-4; noradrenalin, 1407-84-7, 51-41-2; serotonin, 50-67-9 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03056651_v11_n9_p838_Cicardo |
Citas:
---------- APA ----------
Cicardo, V.H., Carneiro de Rondina, D. & Mastronardi, I.O. (1983) . Brain monoamine content in rats treated with the antidepressants mianserin and amoxapine. IRCS Medical Science, 11(9), 838.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03056651_v11_n9_p838_Cicardo [ ]
---------- CHICAGO ----------
Cicardo, V.H., Carneiro de Rondina, D., Mastronardi, I.O. "Brain monoamine content in rats treated with the antidepressants mianserin and amoxapine" . IRCS Medical Science 11, no. 9 (1983) : 838.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03056651_v11_n9_p838_Cicardo [ ]
---------- MLA ----------
Cicardo, V.H., Carneiro de Rondina, D., Mastronardi, I.O. "Brain monoamine content in rats treated with the antidepressants mianserin and amoxapine" . IRCS Medical Science, vol. 11, no. 9, 1983, pp. 838.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03056651_v11_n9_p838_Cicardo [ ]
---------- VANCOUVER ----------
Cicardo, V.H., Carneiro de Rondina, D., Mastronardi, I.O. Brain monoamine content in rats treated with the antidepressants mianserin and amoxapine. IRCS MED. SCI. 1983;11(9):838.Available from: https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03056651_v11_n9_p838_Cicardo [ ]
