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Navone, N.M.; Afonso, S.G.; Polo, C.F.; del C. Battle, A.M. "Uroporhyrinogen decarboxylase from mouse mammary carcinoma and liver of normal and tumor-bearing mouse" (1992) Comparative Biochemistry and Physiology -- Part B: Biochemistry and. 102(1):87-92
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Abstract:

1. 1. URO-D was investigated in crude extracts from mouse mammary carcinoma, normal mouse (NM) liver and tumor-bearing mouse (TBM) liver. 2. 2. URO-D from TBM liver and tumor appears to be more sensitive to increasing concentrations of UROgen than the NM liver enzyme. 3. 3. In tumor the rate-limiting step seems to be the decarboxylation of the first carboxyl group, but this was not so clear for the NM and the TBM liver URO-D. 4. 4. URO-D activity was enhanced when incubated at higher temperatures in the presence of its substrate, suggesting that UROgen might afford some protection of the enzyme against heat inactivation. 5. 5. The optimum pH for all three sources is around 7.0. © 1992.

Registro:

Documento: Artículo
Título:Uroporhyrinogen decarboxylase from mouse mammary carcinoma and liver of normal and tumor-bearing mouse
Autor:Navone, N.M.; Afonso, S.G.; Polo, C.F.; del C. Battle, A.M.
Filiación:Centro de Investigaciones sobre Porfirinas y Porfirias (CIPYP) (CONICET, FCEN, UBA), Ciudad Universitaria, Pabellon II, 2do. Piso, 1428 Buenos Aires, Argentina
Palabras clave:uroporphyrinogen decarboxylase; animal tissue; article; breast cancer; liver; mouse; nonhuman; ph; priority journal; Animal; Hydrogen-Ion Concentration; Kinetics; Liver; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Substrate Specificity; Support, Non-U.S. Gov't; Temperature; Uroporphyrinogen Decarboxylase; Uroporphyrinogens; Animalia
Año:1992
Volumen:102
Número:1
Página de inicio:87
Página de fin:92
DOI: http://dx.doi.org/10.1016/0305-0491(92)90277-X
Título revista:Comparative Biochemistry and Physiology -- Part B: Biochemistry and
ISSN:03050491
CAS:Uroporphyrinogen Decarboxylase, EC 4.1.1.37; Uroporphyrinogens
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03050491_v102_n1_p87_Navone

Referencias:

  • Afonso, Chinarro, Stella, Batlle, Lenczner, Magnin, Uroporfirinógeno decarboxilasa eritrocitaria y hepática en porfiria cutánea tarda (1980) Rev. Arg. Dermatol., 66, pp. 12-24
  • Batlle, Grinstein, Porphyrin biosynthesis (1962) Phyriaporphyrinogen III, a normal intermediate in the biosynthesis of protoporphyrin IX, 62, pp. 197-200. , Biochim. biophys. Acta
  • Batlle, Grinstein, Porphyrin biosynthesis II. Phyriaporphyrinogen III, a normal intermediate in the biosynthesis of haem (1964) Biochim. biophys. Acta, 82, pp. 13-20
  • Batlle, Ferramola, Grinstein, Purification and general properties of δ-aminolaevulate dehydratase from cow liver (1967) Biochem. J., 104, pp. 244-249
  • Batlle, Enriquez de Salamanca, Chinarro, Afonso, Stella, Berges, Wider, Estudio de las condiciones óptimas para la medición de la actividad de la uroporfirinógemo decarboxilasa en sangre (1985) Ann. Med. Intern. (Madrid), 2, pp. 264-268
  • De Verneuil, Grandchamp, Nordmann, Some kinetic properties of human red cell uroporphyrinogen decarboxylase (1980) Biochim. biophys. Acta, 611, pp. 174-186
  • Garcia, San Martin de Viale, Tomio, Grinstein, Porphyrin biosynthesis X. Porphyrinogen carboxylase from avian erythrocytes (1973) Further properties, 309, pp. 203-210. , Biochim. biophys. Acta
  • Jackson, Ferramola, Sancovich, Evans, Matlin, Ryder, Smith, Hepta- and hexa-carboxylic porphyrinogen intermediates in haem biosynthesis (1976) Ann. clin. Res., 8, pp. 64-69
  • Kardish, Woods, Measurement of heme biosynthetic enzymes in mammalian tissues (1980) J. appl. Biochem., 2, pp. 159-167
  • Kawanishi, Seki, Sano, Uroporphyrinogen decarboxylase (1983) Purification, properties and inhibition by polychlorinated biphenyl isomers, 258, pp. 4285-4292. , J. biol. Chem
  • Koopman, Juknat de Geralnik, Batlle, Porphyrin biosynthesis in Rhodopseudomonas palustris V. Purification of porphyrinogen decarboxylase and unusual properties (1986) Int. J. Biochem., 18, pp. 935-944
  • Lowry, Rosebrough, Farr, Randall, Protein measurement with the Folin-phenol reagent (1951) J. biol. Chem., 193, pp. 265-275
  • Mauzerall, Granick, Porphyrin biosynthesis in erythrocytes—III. Uroporphyrinogen and its decarboxylase (1958) J. biol. Chem., 232, pp. 1141-1162
  • Navone, Frisardi, Resnik, Batlle, Polo, Porphyrin biosynthesis in human breast cancer (1988) Preliminary mimetic in vitro studies, 16, pp. 61-62. , Med. Sci. Res
  • Navone, Polo, Frisardi, Batlle, Heme enzyme pattern in mouse mammary carcinoma (1990) Int. J. Biochem., 22, pp. 1410-1411
  • Romeo, Levin, Uroporphyrinogen decarboxylase from mouse spleen (1971) Biochim. biophys. Acta, 230, pp. 330-341
  • Smith, Francis, Decarboxylation of porphyrinogens by rat liver uroporphyrinogen decarboxylase (1979) Biochem. J., 183, pp. 455-458
  • Smith, Francis, Investigations of rat liver uroporphyrinogen decarboxylase (1981) Biochem. J., 195, pp. 241-250
  • Smith, Ferramola, Sancovich, Evans, Matlin, Ryder, Jackson, Pentacarboxylic intermediates in haem biosynthesis (1976) Ann. clin. Res., 8, pp. 89-91
  • Straka, Krushner, Purification and characterization of bovine hepatic uroporphyrinogen decarboxylase (1983) Biochemistry, 22, pp. 4664-4672
  • Tomio, Garcia, San Martin de Viale, Grinstein, Porphyrin biosynthesis—VII. Porphyrinogen carboxylase from avian erythrocytes (1970) Purification and properties, 198, pp. 353-363. , Biochim. biophys. Acta

Citas:

---------- APA ----------
Navone, N.M., Afonso, S.G., Polo, C.F. & del C. Battle, A.M. (1992) . Uroporhyrinogen decarboxylase from mouse mammary carcinoma and liver of normal and tumor-bearing mouse. Comparative Biochemistry and Physiology -- Part B: Biochemistry and, 102(1), 87-92.
http://dx.doi.org/10.1016/0305-0491(92)90277-X
---------- CHICAGO ----------
Navone, N.M., Afonso, S.G., Polo, C.F., del C. Battle, A.M. "Uroporhyrinogen decarboxylase from mouse mammary carcinoma and liver of normal and tumor-bearing mouse" . Comparative Biochemistry and Physiology -- Part B: Biochemistry and 102, no. 1 (1992) : 87-92.
http://dx.doi.org/10.1016/0305-0491(92)90277-X
---------- MLA ----------
Navone, N.M., Afonso, S.G., Polo, C.F., del C. Battle, A.M. "Uroporhyrinogen decarboxylase from mouse mammary carcinoma and liver of normal and tumor-bearing mouse" . Comparative Biochemistry and Physiology -- Part B: Biochemistry and, vol. 102, no. 1, 1992, pp. 87-92.
http://dx.doi.org/10.1016/0305-0491(92)90277-X
---------- VANCOUVER ----------
Navone, N.M., Afonso, S.G., Polo, C.F., del C. Battle, A.M. Uroporhyrinogen decarboxylase from mouse mammary carcinoma and liver of normal and tumor-bearing mouse. 1992;102(1):87-92.
http://dx.doi.org/10.1016/0305-0491(92)90277-X