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Polo, C.F.; Vazquez, E.S.; Del Battle, C.A.M. "Regulation of heme pathway in regenerating mouse liver" (1992) Comparative Biochemistry and Physiology -- Part B: Biochemistry and. 101(1-2):243-246
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Abstract:

1. 1. δ-Aminolevulinic acid synthetase (ALA-S), rhodanese and microsomal heme oxygenase (MHO), were quantitated in Cl4C induced regenerating mouse liver. 2. 2. Maximal hepatomegalia was observed at 48 hr after i.p. injection of a single dose of the toxin. 3. 3. ALA-S activity decreased on day 2, and then significantly increased (50%) between days 3 and 7, returning afterwards to control values. 4. 4. Cytoplasmic rhodanese, as well as MHO activities, exhibited a clear correlation as compared with the ALA-S activity profile. 5. 5. Porphyrin biosynthesis from precursor δ-aminolevulinic acid (ALA) was significantly increased even after 15 days of intoxication. 6. 6. Present results would indicate that Cl4C is acting in a dual fashion. © 1992.

Registro:

Documento: Artículo
Título:Regulation of heme pathway in regenerating mouse liver
Autor:Polo, C.F.; Vazquez, E.S.; Del Battle, C.A.M.
Filiación:Centro de Investigaciones sobre Porfirinas y Porfirias (CIPYP), CONICET, FCEN, Ciudad Universitaria, Pabellon II, 2do Piso, 1428 Buenos Aires, Argentina
Palabras clave:5 aminolevulinate synthase; carbon tetrachloride; heme oxygenase; thiosulfate sulfurtransferase; animal experiment; animal tissue; article; liver regeneration; liver toxicity; mouse; nonhuman; priority journal; 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animal; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Heme; Heme Oxygenase (Decyclizing); Kinetics; Liver; Liver Regeneration; Mice; Microsomes, Liver; Porphyrins; Support, Non-U.S. Gov't; Thiosulfate Sulfurtransferase
Año:1992
Volumen:101
Número:1-2
Página de inicio:243
Página de fin:246
DOI: http://dx.doi.org/10.1016/0305-0491(92)90186-U
Título revista:Comparative Biochemistry and Physiology -- Part B: Biochemistry and
ISSN:03050491
CAS:5 aminolevulinate synthase, 9037-14-3; carbon tetrachloride, 56-23-5; heme oxygenase, 9059-22-7; thiosulfate sulfurtransferase, 9026-04-4; 5-Aminolevulinate Synthetase, EC 2.3.1.37; Aminolevulinic Acid, 106-60-5; Carbon Tetrachloride, 56-23-5; Cytochrome P-450 Enzyme System, 9035-51-2; Heme Oxygenase (Decyclizing), EC 1.14.99.3; Heme, 14875-96-8; Porphyrins; Thiosulfate Sulfurtransferase, EC 2.8.1.1
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03050491_v101_n1-2_p243_Polo

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Citas:

---------- APA ----------
Polo, C.F., Vazquez, E.S. & Del Battle, C.A.M. (1992) . Regulation of heme pathway in regenerating mouse liver. Comparative Biochemistry and Physiology -- Part B: Biochemistry and, 101(1-2), 243-246.
http://dx.doi.org/10.1016/0305-0491(92)90186-U
---------- CHICAGO ----------
Polo, C.F., Vazquez, E.S., Del Battle, C.A.M. "Regulation of heme pathway in regenerating mouse liver" . Comparative Biochemistry and Physiology -- Part B: Biochemistry and 101, no. 1-2 (1992) : 243-246.
http://dx.doi.org/10.1016/0305-0491(92)90186-U
---------- MLA ----------
Polo, C.F., Vazquez, E.S., Del Battle, C.A.M. "Regulation of heme pathway in regenerating mouse liver" . Comparative Biochemistry and Physiology -- Part B: Biochemistry and, vol. 101, no. 1-2, 1992, pp. 243-246.
http://dx.doi.org/10.1016/0305-0491(92)90186-U
---------- VANCOUVER ----------
Polo, C.F., Vazquez, E.S., Del Battle, C.A.M. Regulation of heme pathway in regenerating mouse liver. 1992;101(1-2):243-246.
http://dx.doi.org/10.1016/0305-0491(92)90186-U