Abstract:
Junin virus (JV) infected Veto cells were used to investigate virus capacity to induce cell cell fusion. Polykaryocyte formation due to JV was found to be pH and temperature-dependent. A reduced fusion activity was detected on BHK-21 cells. Different JV-strains exhibited a similar extent and pH dependence of their fusion activity. Neutralizing antibodies against the main viral glycoprotein (GP38) inhibited syncytium production and GP38 conformational changes in response to acid treatment were detected by an immunoprecipitation assay.
Registro:
Documento: |
Artículo
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Título: | Low-pH-induced fusion of Vero cells infected with Junin virus |
Autor: | Castilla, V.; Mersich, S.E. |
Filiación: | Laboratorio de Virología, Fac. de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina Laboratorio de Virología, Depto. Quim. Biológica, Pabellón 2, 1428 Buenos Aires, Argentina
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Palabras clave: | Animalia; Cercopithecus; Junin virus |
Año: | 1996
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Volumen: | 141
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Número: | 7
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Página de inicio: | 1307
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Página de fin: | 1317
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DOI: |
http://dx.doi.org/10.1007/BF01718832 |
Título revista: | Archives of Virology
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Título revista abreviado: | ARCH. VIROL.
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ISSN: | 03048608
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CODEN: | ARVID
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03048608_v141_n7_p1307_Castilla |
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Citas:
---------- APA ----------
Castilla, V. & Mersich, S.E.
(1996)
. Low-pH-induced fusion of Vero cells infected with Junin virus. Archives of Virology, 141(7), 1307-1317.
http://dx.doi.org/10.1007/BF01718832---------- CHICAGO ----------
Castilla, V., Mersich, S.E.
"Low-pH-induced fusion of Vero cells infected with Junin virus"
. Archives of Virology 141, no. 7
(1996) : 1307-1317.
http://dx.doi.org/10.1007/BF01718832---------- MLA ----------
Castilla, V., Mersich, S.E.
"Low-pH-induced fusion of Vero cells infected with Junin virus"
. Archives of Virology, vol. 141, no. 7, 1996, pp. 1307-1317.
http://dx.doi.org/10.1007/BF01718832---------- VANCOUVER ----------
Castilla, V., Mersich, S.E. Low-pH-induced fusion of Vero cells infected with Junin virus. ARCH. VIROL. 1996;141(7):1307-1317.
http://dx.doi.org/10.1007/BF01718832