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Abstract:

Junin virus (JV) infected Veto cells were used to investigate virus capacity to induce cell cell fusion. Polykaryocyte formation due to JV was found to be pH and temperature-dependent. A reduced fusion activity was detected on BHK-21 cells. Different JV-strains exhibited a similar extent and pH dependence of their fusion activity. Neutralizing antibodies against the main viral glycoprotein (GP38) inhibited syncytium production and GP38 conformational changes in response to acid treatment were detected by an immunoprecipitation assay.

Registro:

Documento: Artículo
Título:Low-pH-induced fusion of Vero cells infected with Junin virus
Autor:Castilla, V.; Mersich, S.E.
Filiación:Laboratorio de Virología, Fac. de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
Laboratorio de Virología, Depto. Quim. Biológica, Pabellón 2, 1428 Buenos Aires, Argentina
Palabras clave:Animalia; Cercopithecus; Junin virus
Año:1996
Volumen:141
Número:7
Página de inicio:1307
Página de fin:1317
DOI: http://dx.doi.org/10.1007/BF01718832
Título revista:Archives of Virology
Título revista abreviado:ARCH. VIROL.
ISSN:03048608
CODEN:ARVID
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03048608_v141_n7_p1307_Castilla

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Citas:

---------- APA ----------
Castilla, V. & Mersich, S.E. (1996) . Low-pH-induced fusion of Vero cells infected with Junin virus. Archives of Virology, 141(7), 1307-1317.
http://dx.doi.org/10.1007/BF01718832
---------- CHICAGO ----------
Castilla, V., Mersich, S.E. "Low-pH-induced fusion of Vero cells infected with Junin virus" . Archives of Virology 141, no. 7 (1996) : 1307-1317.
http://dx.doi.org/10.1007/BF01718832
---------- MLA ----------
Castilla, V., Mersich, S.E. "Low-pH-induced fusion of Vero cells infected with Junin virus" . Archives of Virology, vol. 141, no. 7, 1996, pp. 1307-1317.
http://dx.doi.org/10.1007/BF01718832
---------- VANCOUVER ----------
Castilla, V., Mersich, S.E. Low-pH-induced fusion of Vero cells infected with Junin virus. ARCH. VIROL. 1996;141(7):1307-1317.
http://dx.doi.org/10.1007/BF01718832