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Abstract:

Particulate preparations from the chlorophyta Prototheca zopfii catalyze the incorporation of mannose and N-acetylglucosamine into glycolipids. These had been characterized as lipid monophosphate mannose, lipid pyrophosphate N,N′-diacetylchitobiose and various lipid-linked oligosaccharides containing two N-acetylglucosamine residues plus a variable number of mannose residues. The lipid moiety has the properties expected for dolichyl phosphate. The oligosaccharide-linked lipids serve as precursors for the formation of a polymer sensible to pronase digestion. The oligosaccharide is linked by N-glycosidic linkage to an asparagine residue. In longer incubation periods, a polymer insensitive to pronase hydrolysis, but precipitable by copper salts such as cell wall mannans is formed. Polymer formation is inhibited by 1 mM bacitracin. The reactions leading to the formation of the mannoprotein were found associated to the rough endoplasmic reticulum. The synthesis of mannans was found to occur in the Golgi vesicles. © 1979.

Registro:

Documento: Artículo
Título:Lipid carriers in the synthesis of high-mannose glycoproteins in algae
Autor:Romero, P.A.; Hopp, H.E.; Pont Lezica, R.
Filiación:Instituto de Investigaciones Bioquímicas, Fundación Campomar, Obligado 2490, RA, 1428 Buenos Aires, Argentina
Fachbereich Biologie, Universität Kaiserslautern, Postfach 3049, D-6750 Kaiserslautern, Germany
Palabras clave:(Alga); Bacitracin; Dolichyl phosphate; Glycoprotein synthesis; High-mannose glycoprotein; bacitracin; glycolipid; glycoprotein; mannose; n acetylglucosamine; oligosaccharide; alga; article; biosynthesis; intracellular membrane; metabolism; Acetylglucosamine; Algae, Green; Bacitracin; Glycolipids; Glycoproteins; Intracellular Membranes; Mannose; Oligosaccharides
Año:1979
Volumen:586
Número:3
Página de inicio:545
Página de fin:559
DOI: http://dx.doi.org/10.1016/0304-4165(79)90045-X
Título revista:BBA - General Subjects
Título revista abreviado:Biochim. Biophys. Acta Gen. Subj.
ISSN:03044165
CODEN:BBGSB
CAS:bacitracin, 1405-87-4; mannose, 31103-86-3, 3458-28-4; n acetylglucosamine, 7512-17-6; Acetylglucosamine, 7512-17-6; Bacitracin, 1405-87-4; Glycolipids; Glycoproteins; Mannose, 31103-86-3; Oligosaccharides
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03044165_v586_n3_p545_Romero

Referencias:

  • Kauss, (1969) FEBS Lett., 5, pp. 81-84
  • Alam, Hemming, (1973) Phytochemistry, 12, pp. 1641-1649
  • Forsee, Elbein, (1975) J. Biol. Chem., 250, pp. 9281-9293
  • Lehle, Fartaczek, Tanner, Kauss, (1976) Arch. Biochem. Biophys., 175, pp. 419-426
  • Beevers, Mense, Glycoprotein Biosynthesis in Cotyledons of Pisum sativum L: Involvement of Lipid-linked Intermediates (1977) PLANT PHYSIOLOGY, 60, pp. 703-708
  • Brett, Leloir, (1977) Biochem. J., 161, pp. 93-101
  • Ericson, Delmer, Glycoprotein Synthesis in Plants: I. Role of Lipid Intermediates (1977) PLANT PHYSIOLOGY, 59, pp. 341-347
  • Pont Lezica, Romero, Hopp, (1978) Planta, 140, pp. 177-183
  • Behrens, (1974) Biology and Chemistry of Eucaryotic Cell Surfaces, pp. 159-178. , E.Y.C. Lee, E.E. Smith, Academic Press, New York
  • Parodi, Leloir, (1976) Trends Biochem. Sci., 1, pp. 58-59
  • Waechter, Lennarz, The Role of Polyprenol-Linked Sugars in Glycoprotein Synthesis (1976) Annual Review of Biochemistry, 41, pp. 95-112
  • Hemming, (1977) Biochem. Soc. Trans., 5, pp. 1223-1231
  • Kornfeld, Kornfeld, Comparative Aspects of Glycoprotein Structure (1976) Annual Review of Biochemistry, 41, pp. 217-237
  • Robbins, Hubbard, Turco, Wirth, (1977) Cell, 12, pp. 893-900
  • Li, Li, (1972) Methods Enzymol., 28, pp. 702-713
  • Behrens, Tábora, (1978) Methods Enzymol., 50, pp. 402-435
  • Hopp, Daleo, Romero, Pont Lezica, Biosynthesis of Dolichyl Phosphate: Characterization and Site of Synthesis in Algae (1978) PLANT PHYSIOLOGY, 61, pp. 248-251
  • Hopp, Romero, Daleo, Pont Lezica, (1979) Biochemistry and Physiology of Plant Lipids, pp. 313-318. , L.A. Appelqvist, C. Liljenberg, Elsevier/North-Holland, Amsterdam
  • Algranati, Behrens, Carminatti, Cabib, (1966) Methods Enzymol., 8, pp. 411-416
  • Staneloni, Leloir, (1978) Proc. Natl. Acad. Sci. U.S., 75, pp. 1162-1166. , 2nd edn
  • Lowry, Rosenbrough, Farr, Randall, (1951) J. Biol. Chem., 193, pp. 265-275
  • Trevelyan, Procter, Harrison, (1950) Nature, 166, pp. 444-445
  • Siegel, Brady, Awad, (1972) J. Biol. Chem., 247, pp. 4155-4159
  • Tábora, (1976) Ph.D. Thesis, , 2nd edn., Universidad de Buenos Aires, Argentina
  • Siewert, Strominger, BACITRACIN: AN INHIBITOR OF THE DEPHOSPHORYLATION OF LIPID PYROPHOSPHATE, AN INTERMEDIATE IN THE BIOSYNTHESIS OF THE PEPTIDOGLYCAN OF BACTERIAL CELL WALLS (1976) Proceedings of the National Academy of Sciences, 57, pp. 767-773. , 2nd edn
  • Lord, Kagawa, Moore, Beevers, (1973) J. Cell. Biol., 57, pp. 659-667
  • Shore, Maclachlan, (1975) J. Cell. Biol., 64, pp. 557-571
  • Forsee, Elbein, (1973) J. Biol. Chem., 248, pp. 2858-2867
  • Tanner, Jung, Behrens, (1971) FEBS Lett., 16, pp. 245-248
  • Leloir, Staneloni, Carminatti, Behrens, (1973) Biochem. Biophys. Res. Commun., 52, pp. 1285-1292
  • Lehle, Tanner, (1975) Biochim. Biophys. Acta, 399, pp. 364-374
  • Chen, Lennarz, Tarentino, Maley, (1975) J. Biol. Chem., 250, pp. 7006-7013
  • Reuvers, Boer, Hemming, (1978) Biochem. J., 169, pp. 505-508
  • Herscovics, Warren, Bugge, Jeanloz, (1978) J. Biol. Chem., 253, pp. 160-165
  • Ericson, Gafford, Elbein, Evidence That the Lipid Carrier for N-Acetylglucosamine Is Different from That for Mannose in Mung Beans and Cotton Fibers (1978) PLANT PHYSIOLOGY, 61, pp. 274-277
  • Sharma, Babczinski, Lehle, Tanner, (1974) Eur. J. Biochem., 46, pp. 35-41
  • Tabas, Schlesinger, Kornfeld, (1978) J. Biol. Chem., 253, pp. 716-722
  • Hercovics, Bugge, Jeanloz, (1977) FEBS Lett., 82, pp. 215-218
  • Ericson, Elbein, (1978) Plant Physiol., 61, pp. S-40
  • Reuvers, Boer, Steyn-Parve, (1978) Biochem. Biophys. Res. Commun., 82, pp. 800-804
  • Lehle, Bowles, Tanner, (1978) Plant Sci. Lett., 11, pp. 27-34
  • Nagahashi, Beevers, Subcellular Localization of Glycosyl Transferases Involved in Glycoprotein Biosynthesis in the Cotyledons of Pisum sativum L. (1978) PLANT PHYSIOLOGY, 61, pp. 451-459

Citas:

---------- APA ----------
Romero, P.A., Hopp, H.E. & Pont Lezica, R. (1979) . Lipid carriers in the synthesis of high-mannose glycoproteins in algae. BBA - General Subjects, 586(3), 545-559.
http://dx.doi.org/10.1016/0304-4165(79)90045-X
---------- CHICAGO ----------
Romero, P.A., Hopp, H.E., Pont Lezica, R. "Lipid carriers in the synthesis of high-mannose glycoproteins in algae" . BBA - General Subjects 586, no. 3 (1979) : 545-559.
http://dx.doi.org/10.1016/0304-4165(79)90045-X
---------- MLA ----------
Romero, P.A., Hopp, H.E., Pont Lezica, R. "Lipid carriers in the synthesis of high-mannose glycoproteins in algae" . BBA - General Subjects, vol. 586, no. 3, 1979, pp. 545-559.
http://dx.doi.org/10.1016/0304-4165(79)90045-X
---------- VANCOUVER ----------
Romero, P.A., Hopp, H.E., Pont Lezica, R. Lipid carriers in the synthesis of high-mannose glycoproteins in algae. Biochim. Biophys. Acta Gen. Subj. 1979;586(3):545-559.
http://dx.doi.org/10.1016/0304-4165(79)90045-X