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Enriquez, G.F.; Garbossa, G.; Macchiaverna, N.P.; Argibay, H.D.; Bua, J.; Gürtler, R.E.; Cardinal, M.V. "Is the infectiousness of dogs naturally infected with Trypanosoma cruzi associated with poly-parasitism?" (2016) Veterinary Parasitology. 223:186-194
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Abstract:

Interactions among different species of parasites co-infecting the same host could be synergistic or antagonistic. These interactions may modify both the frequency of infected hosts and their infectiousness, and therefore impact on transmission dynamics. This study determined the infectiousness of Trypanosoma cruzi-seropositive dogs (using xenodiagnosis) and their parasite load (quantified by qPCR), and tested the association between both variables and the presence of concomitant endoparasites. A cross-sectional serosurvey conducted in eight rural villages from Pampa del Indio and neighboring municipalities (northeastern Argentina) detected 32 T. cruzi-seropositive dogs out of 217 individuals examined for infection. Both the infectiousness to the vector Triatoma infestans and parasite load of T. cruzi-seropositive dogs examined were heterogeneous. A statistically significant, nine-fold higher mean infectiousness was registered in T. cruzi-seropositive dogs co-infected with Ancylostoma caninum and a trematode than in T. cruzi-seropositive dogs without these infections. The median parasite load of T. cruzi was also significantly higher in dogs co-infected with these helminths. An opposite trend was observed in T. cruzi-seropositive dogs that were serologically positive to Toxoplasma gondii or Neospora caninum relative to dogs seronegative for these parasites. Using multiple logistic regression analysis with random effects, we found a positive and significant association between the infectiousness of T. cruzi-seropositive dogs and co-infections with A. caninum and a trematode. Our results suggest that co-infections may be a modifier of host infectiousness in dogs naturally infected with T. cruzi. © 2016 Elsevier B.V.

Registro:

Documento: Artículo
Título:Is the infectiousness of dogs naturally infected with Trypanosoma cruzi associated with poly-parasitism?
Autor:Enriquez, G.F.; Garbossa, G.; Macchiaverna, N.P.; Argibay, H.D.; Bua, J.; Gürtler, R.E.; Cardinal, M.V.
Filiación:Laboratory of Eco-Epidemiology, Faculty of Exact and Natural Sciences, University of Buenos Aires, Argentina
Institute of Ecology, Genetics and Evolution of Buenos Aires (UBA-CONICET), Argentina
Laboratory of Clinical and Environmental Parasitology, Faculty of Exact and Natural Sciences, University of Buenos Aires, (IQUIBICEN-CONICET-UBA), Public Health Research Institute, Argentina
National Institute of Parasitology Dr. M. Fatala Chaben, National Administration of Laboratories and Inst.s of Health Dr. C.G. Malbrán, Buenos Aires, Argentina
Palabras clave:Dogs; Infectiousness; Interspecies interactions; Poly-parasitism; Trypanosoma cruzi; adult; Ancylostoma caninum; animal experiment; Argentina; Article; Chagas disease; controlled study; cross-sectional study; disease transmission; host parasite interaction; Neospora caninum; nonhuman; parasite load; parasitism; polymerase chain reaction; polyparasitism; rural area; Toxoplasma gondii; Triatoma infestans; Trypanosoma cruzi; xenodiagnosis; animal; animal parasitosis; Chagas disease; complication; dog; dog disease; isolation and purification; mixed infection; parasitology; pathology; veterinary; Animals; Chagas Disease; Coinfection; Dog Diseases; Dogs; Helminthiasis, Animal; Trypanosoma cruzi
Año:2016
Volumen:223
Página de inicio:186
Página de fin:194
DOI: http://dx.doi.org/10.1016/j.vetpar.2016.04.042
Título revista:Veterinary Parasitology
Título revista abreviado:Vet. Parasitol.
ISSN:03044017
CODEN:VPARD
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03044017_v223_n_p186_Enriquez

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Citas:

---------- APA ----------
Enriquez, G.F., Garbossa, G., Macchiaverna, N.P., Argibay, H.D., Bua, J., Gürtler, R.E. & Cardinal, M.V. (2016) . Is the infectiousness of dogs naturally infected with Trypanosoma cruzi associated with poly-parasitism?. Veterinary Parasitology, 223, 186-194.
http://dx.doi.org/10.1016/j.vetpar.2016.04.042
---------- CHICAGO ----------
Enriquez, G.F., Garbossa, G., Macchiaverna, N.P., Argibay, H.D., Bua, J., Gürtler, R.E., et al. "Is the infectiousness of dogs naturally infected with Trypanosoma cruzi associated with poly-parasitism?" . Veterinary Parasitology 223 (2016) : 186-194.
http://dx.doi.org/10.1016/j.vetpar.2016.04.042
---------- MLA ----------
Enriquez, G.F., Garbossa, G., Macchiaverna, N.P., Argibay, H.D., Bua, J., Gürtler, R.E., et al. "Is the infectiousness of dogs naturally infected with Trypanosoma cruzi associated with poly-parasitism?" . Veterinary Parasitology, vol. 223, 2016, pp. 186-194.
http://dx.doi.org/10.1016/j.vetpar.2016.04.042
---------- VANCOUVER ----------
Enriquez, G.F., Garbossa, G., Macchiaverna, N.P., Argibay, H.D., Bua, J., Gürtler, R.E., et al. Is the infectiousness of dogs naturally infected with Trypanosoma cruzi associated with poly-parasitism?. Vet. Parasitol. 2016;223:186-194.
http://dx.doi.org/10.1016/j.vetpar.2016.04.042