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Abstract:

Before the memory trace is stored long term, it must undergo a phase of consolidation during which it remains susceptible to modifications. It has previously been proposed that during consolidation, memories are kept from being stored long term, and can therefore be modified with additional information resulting from ongoing behavior. The Chasmagnathus associative memory model is used here to test whether it is possible during consolidation to modify the long-term expression of a memory generated by a weak training procedure. In this memory model, long-term memory expression is achieved after strong training protocols, a 15-spaced trial procedure. After a weak training protocol (WTP, six spaced trials), crabs do not show memory retention when tested in the long term. Nevertheless, the WTP builds a long-term memory that it is indeed consolidated, but remains unexpressed. Here we show that memory can be modified by experience during this short period after learning: memory expression can be enhanced by a Single Trial Session, on the condition that this session takes place contingent upon the consolidation period. We also found that during this time, the memory built by the WTP is behaviorally expressed, in contrast with what occurs at long term. Our results support the idea that during consolidation memories can be evaluated in the background of concurrent experiences. In particular, we propose that during the consolidation period it is possible for crabs to assess which experiences, among those stored long term, will be expressed long term. © 2010 Elsevier Ireland Ltd.

Registro:

Documento: Artículo
Título:Enhancement of long-term memory expression by a single trial during consolidation
Autor:Smal, L.; Suárez, L.D.; Delorenzi, A.
Filiación:Laboratorio de Neurobiología de la Memoria, Departamento de Fisiología y Biología Molecular y Celular, FCEyN, Universidad de Buenos Aires, IFIBYNE-CONICET, Argentina
Palabras clave:Consolidation; Memory; Memory enhancement; Memory update; Short-term memory; article; associative memory; controlled study; crab; long term memory; male; memory consolidation; nonhuman; priority journal; short term memory; training; Animals; Association Learning; Behavior, Animal; Brachyura; Conditioning, Classical; Male; Memory, Long-Term; Time Factors
Año:2011
Volumen:487
Número:1
Página de inicio:36
Página de fin:40
DOI: http://dx.doi.org/10.1016/j.neulet.2010.09.069
Título revista:Neuroscience Letters
Título revista abreviado:Neurosci. Lett.
ISSN:03043940
CODEN:NELED
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03043940_v487_n1_p36_Smal

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Citas:

---------- APA ----------
Smal, L., Suárez, L.D. & Delorenzi, A. (2011) . Enhancement of long-term memory expression by a single trial during consolidation. Neuroscience Letters, 487(1), 36-40.
http://dx.doi.org/10.1016/j.neulet.2010.09.069
---------- CHICAGO ----------
Smal, L., Suárez, L.D., Delorenzi, A. "Enhancement of long-term memory expression by a single trial during consolidation" . Neuroscience Letters 487, no. 1 (2011) : 36-40.
http://dx.doi.org/10.1016/j.neulet.2010.09.069
---------- MLA ----------
Smal, L., Suárez, L.D., Delorenzi, A. "Enhancement of long-term memory expression by a single trial during consolidation" . Neuroscience Letters, vol. 487, no. 1, 2011, pp. 36-40.
http://dx.doi.org/10.1016/j.neulet.2010.09.069
---------- VANCOUVER ----------
Smal, L., Suárez, L.D., Delorenzi, A. Enhancement of long-term memory expression by a single trial during consolidation. Neurosci. Lett. 2011;487(1):36-40.
http://dx.doi.org/10.1016/j.neulet.2010.09.069