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Abstract:

In yeasts, several sensing systems localized to the plasma membrane which transduce information regarding the availability and quality of nitrogen and carbon sources and work in parallel with the intracellular nutrient-sensing systems, regulate the expression and activity of proteins involved in nutrient uptake and utilization. The aim of this work was to establish whether the cellular signals triggered by amino acids modify the expression of the UGA4 gene which encodes the δ-aminolevulinic (ALA) and γ-aminobutyric (GABA) acids permease. In the present paper, we demonstrate that extracellular amino acids regulate UGA4 expression and that this effect seems to be mediated by the amino acid sensor complex SPS (SSY1, PTR3, SSY5). © Springer-Verlag 2005.

Registro:

Documento: Artículo
Título:Expression of the UGA4 gene encoding the δ-aminolevulinic and γ-aminobutyric acids permease in Saccharomyces cerevisiae is controlled by amino acid-sensing systems
Autor:Bermudez Moretti, M.; Perullini, A.M.; Batlle, A.; Correa Garcia, S.
Filiación:Departamento de Química Biológica (FCEyN, UBA), Ciudad Universitaria, Pabellón II, 1428 Buenos Aires, Argentina
Departamento de Fisiología Y Biología Molecular Y Celular (FCEyN, UBA), Ciudad Universitaria, Pabellón II, 1428 Buenos Aires, Argentina
Centro de Investigaciones Sobre Porfirinas Y Porfirias (CIPYP), CONICET, Pabellón II, 1428 Buenos Aires, Argentina
Rivadavia 1583 9 B, 1033 Buenos Aires, Argentina
Palabras clave:Gene expression; Saccharomyces cerevisiae; Sensor systems; UGA4 gene; 4 aminobutyric acid; amino acid; aminolevulinic acid; article; gene; gene control; gene expression; molecular dynamics; nonhuman; priority journal; regulatory mechanism; Saccharomyces cerevisiae; signal transduction; UGA4 gene; Amino Acid Transport Systems; Aminolevulinic Acid; Carrier Proteins; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Gene Expression Regulation, Fungal; Membrane Proteins; Organic Anion Transporters; Saccharomyces cerevisiae Proteins; Saccharomyces cerevisiae
Año:2005
Volumen:184
Número:2
Página de inicio:137
Página de fin:140
DOI: http://dx.doi.org/10.1007/s00203-005-0022-3
Título revista:Archives of Microbiology
Título revista abreviado:Arch. Microbiol.
ISSN:03028933
CODEN:AMICC
CAS:4 aminobutyric acid, 28805-76-7, 56-12-2; amino acid, 65072-01-7; aminolevulinic acid, 106-60-5; Amino Acid Transport Systems; Aminolevulinic Acid, 106-60-5; Carrier Proteins; GABA permease, 69913-01-5; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid, 56-12-2; Membrane Proteins; Organic Anion Transporters; PTR3 protein, S cerevisiae; Saccharomyces cerevisiae Proteins; SSY1 protein, S cerevisiae; UGA4 protein, S cerevisiae
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03028933_v184_n2_p137_BermudezMoretti

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Citas:

---------- APA ----------
Bermudez Moretti, M., Perullini, A.M., Batlle, A. & Correa Garcia, S. (2005) . Expression of the UGA4 gene encoding the δ-aminolevulinic and γ-aminobutyric acids permease in Saccharomyces cerevisiae is controlled by amino acid-sensing systems. Archives of Microbiology, 184(2), 137-140.
http://dx.doi.org/10.1007/s00203-005-0022-3
---------- CHICAGO ----------
Bermudez Moretti, M., Perullini, A.M., Batlle, A., Correa Garcia, S. "Expression of the UGA4 gene encoding the δ-aminolevulinic and γ-aminobutyric acids permease in Saccharomyces cerevisiae is controlled by amino acid-sensing systems" . Archives of Microbiology 184, no. 2 (2005) : 137-140.
http://dx.doi.org/10.1007/s00203-005-0022-3
---------- MLA ----------
Bermudez Moretti, M., Perullini, A.M., Batlle, A., Correa Garcia, S. "Expression of the UGA4 gene encoding the δ-aminolevulinic and γ-aminobutyric acids permease in Saccharomyces cerevisiae is controlled by amino acid-sensing systems" . Archives of Microbiology, vol. 184, no. 2, 2005, pp. 137-140.
http://dx.doi.org/10.1007/s00203-005-0022-3
---------- VANCOUVER ----------
Bermudez Moretti, M., Perullini, A.M., Batlle, A., Correa Garcia, S. Expression of the UGA4 gene encoding the δ-aminolevulinic and γ-aminobutyric acids permease in Saccharomyces cerevisiae is controlled by amino acid-sensing systems. Arch. Microbiol. 2005;184(2):137-140.
http://dx.doi.org/10.1007/s00203-005-0022-3