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Abstract:

1. 1. Systemic administration of angiotensin II (10 μg/kg) to fully hydrated toads decreased urine production but did not affect natripheric or hydrosmotic water fluxes across the skin. 2. 2. The antidiuretic response was not modified by the simultaneous α-adrenergic blocking with tolazoline (5 mg/kg). 3. 3. In a similar way, single intracerebroventricular injections of 1 μl 10-4M angiotensin II, decreased urine production but did not affect water uptake. 4. 4. Finally, systemic injections of the angiotensin blocker salarasin (100 μg/kg) did not affect the cutaneous hydrosmotic response of dehydrated toads. 5. 5. We conclude that angiotensin II has no effects on water uptake in this species. The antidiuretic response to angiotensin II, and the involvement of adrenergic mechanisms are discussed. © 1989.

Registro:

Documento: Artículo
Título:Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum
Autor:Reboreda, J.C.; Segura, E.T.
Filiación:Instituto de Biologia y Medicina Experimental (CONICET), Obligado 2490, Buenos Aires, 1428, Argentina
Palabras clave:angiotensin; saralasin; tolazoline; animal experiment; controlled study; fluid balance; intracerebroventricular drug administration; intralymphatic drug administration; male; nonhuman; osmoregulation; toad; uropoiesis
Año:1989
Volumen:93
Número:3
Página de inicio:505
Página de fin:509
DOI: http://dx.doi.org/10.1016/0300-9629(89)90002-9
Título revista:Comparative Biochemistry and Physiology -- Part A: Physiology
ISSN:03009629
CAS:angiotensin, 11128-99-7, 1407-47-2; saralasin, 34273-10-4; tolazoline, 59-97-2, 59-98-3
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03009629_v93_n3_p505_Reboreda

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Citas:

---------- APA ----------
Reboreda, J.C. & Segura, E.T. (1989) . Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum. Comparative Biochemistry and Physiology -- Part A: Physiology, 93(3), 505-509.
http://dx.doi.org/10.1016/0300-9629(89)90002-9
---------- CHICAGO ----------
Reboreda, J.C., Segura, E.T. "Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum" . Comparative Biochemistry and Physiology -- Part A: Physiology 93, no. 3 (1989) : 505-509.
http://dx.doi.org/10.1016/0300-9629(89)90002-9
---------- MLA ----------
Reboreda, J.C., Segura, E.T. "Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum" . Comparative Biochemistry and Physiology -- Part A: Physiology, vol. 93, no. 3, 1989, pp. 505-509.
http://dx.doi.org/10.1016/0300-9629(89)90002-9
---------- VANCOUVER ----------
Reboreda, J.C., Segura, E.T. Water balance effects of systemic and intracerebroventricular administration of angiotensin II in the toad Bufo arenarum. 1989;93(3):505-509.
http://dx.doi.org/10.1016/0300-9629(89)90002-9