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Abstract:

Introduction and objectives Thoracic aorta calcium detection is known to improve cardiovascular risk prediction for cardiac and noncardiac events beyond traditional risk factors. We investigated the influence of thoracic aorta morphometry on the presence and extent of aortic calcifications. Methods Nonenhanced computed tomography heart scans were performed in 970 asymptomatic participants at increased cardiovascular risk. An automated algorithm estimated the geometry of the entire thoracic aorta and quantified the aortic calcium Agatston score. A nonparametric model was used to analyze the percentiles of calcium score by age. Logistic regression models were calculated to identify anatomical associations with calcium levels. Results Calcifications were concentrated in the aortic arch and descending portions. Higher amounts of calcium were associated with an enlarged, unfolded, less tapered and more tortuous aorta. The size of the ascending aorta was not correlated with aortic calcium score, whereas enlargement of the descending aorta had the strongest association: the risk of having a global calcium score > 90th percentile was 3.62 times higher (confidence interval, 2.30-5.91; P < .001) for each 2.5-mm increase in descending aorta diameter. Vessel taper, tortuosity, unfolding and aortic arch and descending volumes were also correlated with higher amounts of calcium. Conclusions Thoracic aorta calcium was predominantly found at the arch and descending aorta and was positively associated with the size of the descending aorta and the aortic arch, but not with the size of the ascending aorta. These findings suggest that aortic dilatation may have different mechanisms and may consequently require different preventive strategies according to the considered segments. Full English text available from: www.revespcardiol.org/en © 2016 Sociedad Española de Cardiología

Registro:

Documento: Artículo
Título:Association Between Thoracic Aorta Calcium and Thoracic Aorta Geometry in a Cohort of Asymptomatic Participants at Increased Cardiovascular Risk
Autor:Craiem, D.; Alsac, J.-M.; Casciaro, M.E.; El Batti, S.; Mousseaux, E.; Sirieix, M.-E.; Simon, A.
Filiación:Facultad de Ingeniería, Ciencias Exactas y Naturales, Universidad Favaloro, CONICET, Buenos Aires, Argentina
Centre de Médecine Préventive Cardiovasculaire, APHP, Hôpital Européen Georges Pompidou, París, France
INSERM U970, APHP, Hôpital Européen Georges Pompidou, París, France
Université Paris-Descartes, Paris-Centre de Recherche Cardiovasculaire, Hôpital Européen Georges Pompidou, París, France
Service de Chirurgie Cardiaque et Vasculaire, APHP, Hôpital Européen Georges Pompidou, París, France
Service d'Imagerie Cardiovasculaire, APHP, Hôpital Européen Georges Pompidou, París, France
Palabras clave:Aorta; Atherosclerosis; Calcium; Computed tomography; calcium; Aortic Diseases; asymptomatic disease; Cardiovascular Diseases; clinical trial; diagnostic imaging; female; health; human; incidence; male; metabolism; middle aged; multicenter study; multidetector computed tomography; procedures; retrospective study; risk assessment; risk factor; thoracic aorta; Aorta, Thoracic; Aortic Diseases; Asymptomatic Diseases; Calcium; Cardiovascular Diseases; Female; Global Health; Humans; Incidence; Male; Middle Aged; Multidetector Computed Tomography; Retrospective Studies; Risk Assessment; Risk Factors
Año:2016
Volumen:69
Número:9
Página de inicio:827
Página de fin:835
DOI: http://dx.doi.org/10.1016/j.recesp.2016.01.037
Título revista:Revista Espanola de Cardiologia
Título revista abreviado:Rev. Esp. Cardiol.
ISSN:03008932
CODEN:RCDOA
CAS:calcium, 7440-70-2, 14092-94-5; Calcium
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03008932_v69_n9_p827_Craiem

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Citas:

---------- APA ----------
Craiem, D., Alsac, J.-M., Casciaro, M.E., El Batti, S., Mousseaux, E., Sirieix, M.-E. & Simon, A. (2016) . Association Between Thoracic Aorta Calcium and Thoracic Aorta Geometry in a Cohort of Asymptomatic Participants at Increased Cardiovascular Risk . Revista Espanola de Cardiologia, 69(9), 827-835.
http://dx.doi.org/10.1016/j.recesp.2016.01.037
---------- CHICAGO ----------
Craiem, D., Alsac, J.-M., Casciaro, M.E., El Batti, S., Mousseaux, E., Sirieix, M.-E., et al. "Association Between Thoracic Aorta Calcium and Thoracic Aorta Geometry in a Cohort of Asymptomatic Participants at Increased Cardiovascular Risk " . Revista Espanola de Cardiologia 69, no. 9 (2016) : 827-835.
http://dx.doi.org/10.1016/j.recesp.2016.01.037
---------- MLA ----------
Craiem, D., Alsac, J.-M., Casciaro, M.E., El Batti, S., Mousseaux, E., Sirieix, M.-E., et al. "Association Between Thoracic Aorta Calcium and Thoracic Aorta Geometry in a Cohort of Asymptomatic Participants at Increased Cardiovascular Risk " . Revista Espanola de Cardiologia, vol. 69, no. 9, 2016, pp. 827-835.
http://dx.doi.org/10.1016/j.recesp.2016.01.037
---------- VANCOUVER ----------
Craiem, D., Alsac, J.-M., Casciaro, M.E., El Batti, S., Mousseaux, E., Sirieix, M.-E., et al. Association Between Thoracic Aorta Calcium and Thoracic Aorta Geometry in a Cohort of Asymptomatic Participants at Increased Cardiovascular Risk . Rev. Esp. Cardiol. 2016;69(9):827-835.
http://dx.doi.org/10.1016/j.recesp.2016.01.037