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Abstract:

Experiments with invertebrates support the view that intracellular events subserving the consolidation phase of memory are preserved across evolution. Here, we investigate whether such evolutionary persistence extends to reconsolidation mechanisms, which have recently received special attention in vertebrate studies. For this purpose, the memory model of the crab Chasmagnathus is used. A visual danger stimulus (VDS) elicits crab escaping, which declines after a few stimulus presentations. The long-lasting retention of this decrement, called context-signal memory (CSM), is mediated by an association between contextual cues of the training site and the VDS. The present results show amnesia for CSM in crabs re-exposed at 24 hr (day 2) for 5 min to the learning context, 24 hr after training, and injected with one of two amnesic agents, then tested 24 hr later. Agents and timing were either 15 μg of cycloheximide given between 1 hr before and 4 hr after re-exposure or 1 μg/gm (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine given between 1 hr before and 2 hr after re-exposure. The amnesic effects are specific to behavior that occurs a long time after reactivation but not a short time after. No CSM deficit is produced by such agents when crabs are exposed to a context different from that of training. Findings are consistent with those reported for vertebrates, with both showing that reactivation induces a recapitulation of the postacquisition cascade of intracellular events. The agreement between results from such phylogenetically disparate animals suggests that evolution may have adopted a given molecular cascade as the preferred means of encoding experiences in the nervous system.

Registro:

Documento: Artículo
Título:Reactivation and reconsolidation of long-term memory in the crab Chasmagnathus: Protein synthesis requirement and mediation by NMDA-type glutamatergic receptors
Autor:Pedreira, M.E.; Pérez-Cuesta, L.M.; Maldonado, H.
Filiación:Lab. Neurobiologia de la Memoria, Facultad Ciencias Exact. Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
Palabras clave:Context reminder; Crab; Crustacea; Cycloheximide; Invertebrate; Memory; MK-801; Reactivation; Reconsolidation; cycloheximide; dizocilpine; glutamate receptor; n methyl dextro aspartic acid receptor; amnesia; animal cell; animal experiment; animal model; article; cell activity; chasmagnathus; context signal memory; crab; disease model; dose time effect relation; escape behavior; invertebrate; long term memory; male; memory; molecular evolution; molecular phylogeny; nervous system function; nonhuman; phylogeny; priority journal; protein synthesis; receptor binding; signal processing; training; visual stimulation; Amnesia; Animals; Behavior, Animal; Brachyura; Cycloheximide; Dizocilpine Maleate; Drug Administration Schedule; Escape Reaction; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Memory; Photic Stimulation; Protein Biosynthesis; Protein Synthesis Inhibitors; Receptors, N-Methyl-D-Aspartate; Retention (Psychology); Time Factors
Año:2002
Volumen:22
Número:18
Página de inicio:8305
Página de fin:8311
Título revista:Journal of Neuroscience
Título revista abreviado:J. Neurosci.
ISSN:02706474
CODEN:JNRSD
CAS:Cycloheximide, 66-81-9; Dizocilpine Maleate, 77086-22-7; Excitatory Amino Acid Antagonists; Glutamic Acid, 56-86-0; Protein Synthesis Inhibitors; Receptors, N-Methyl-D-Aspartate
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_02706474_v22_n18_p8305_Pedreira

Referencias:

  • Abel, T., Kandel, E.R., Positive and negative regulatory mechanisms that mediated long-term memory storage (1998) Brain Res Brain Res Rev, 26, pp. 360-378
  • Alberini, M.C., Genes to remember (1999) J Exp Biol, 202, pp. 2887-2891
  • Applewhite, B.P., Gardner, F.T., Lapan, E., Physiology of habituation learning in a protozoan (1969) Trans NY Acad Sci, 31, pp. 842-849
  • Berón de Astrada, M., Maldonado, H., Two related forms of long-term habituation in the crab Chasmagnathus are differentially affected by scopolamine (1999) Pharmacol Biochem Behav, 63, pp. 109-118
  • Carew, T.J., (2000) Behavioral Neurobiology: The Cellular Organization of Natural Behavior, , Sunderland, MA: Sinauer
  • Delorenzi, A., Pedreira, M.E., Romano, A., García, S.I., Pirola, C.J., Nahmod, V.E., Maldonado, H., Acute administration of angiotensin II enhances long-term memory in the crab Chasmagnathus (1996) Brain Res Bull, 41, pp. 211-220
  • Delorenzi, A., Dimant, B., Frenkel, L., Nahmod, V., Nassel, D., Maldonado, H., High environmental salinity induces memory enhancement and increases brain angiotensin-like peptides in the crab Chasmagnathus (2000) J Exp Biol, 203, pp. 3369-3379
  • Freudenthal, R., Romano, A., Participation of Rel/NFΚB transcription factors in long-term memory in the crab Chasmagnathus (2000) Brain Res, 885, pp. 274-281
  • Freudenthal, R., Locatelli, F., Hermitte, G., Maldonado, H., Delorenzi, A., Romano, A., ΚB-like DNA binding activity is enhanced after spaced training that induces long-term memory in the crab Chasmagnathus (1998) Neurosci Lett, 242, pp. 143-146
  • Hermitte, G., Pedreira, M.E., Tomsic, D., Maldonado, H., Context shift and protein synthesis inhibition disrupt long-term habituation after spaced, but not massed, training in the crab Chasmagnathus (1999) Neurobiol Learn Mem, 71, pp. 34-49
  • Hoeger, R., Florey, E., Catecholamine degradation in the hemolymph of the Chinese crab, Eriocheir sinesis (1989) Comp Biochem Physiol, 92 C, pp. 323-327
  • Howell, D.C., (1987) Statistical Methods for Psychology, , Boston: Duxbury
  • Judge, M.E., Quartermain, D., Alleviation of anisomycin-induced amnesia by pre-test treatment with lysine-vasopressin (1982) Pharmacol Biochem Behav, 16, pp. 463-466
  • Locatelli, F., Lafourcade, C., Maldonado, H., Romano, A., Characterization of cAMP-dependent protein kinase isoforms in the brain of the crab Chasmagnathus (2000) J Comp Physiol [B], 171, pp. 33-40
  • Locatelli, F., Maldonado, H., Romano, A., Two critical periods for cAMP dependent protein kinase activity during long-term memory consolidation in the crab Chasmagnathus (2002) Neurobiol Learn Mem, 77, pp. 234-349
  • Lozada, M., Romano, A., Maldonado, H., Long-term habituation to a danger stimulus in the crab Chasmagnathus granulatus (1990) Physiol Behav, 47, pp. 35-41
  • Maldonado, H., Crustacean as model to investigate memory illustrated by extensive behavioral and physiological studies in Chasmagnathus (2002) The Crustacean Nervous System, pp. 314-327. , Wiese K, ed. Springer: Berlin
  • Menzel, R., Searching for the memory trace in a mini-brain, the honeybee (2001) Learn Mem, 8, pp. 53-62
  • Merlo, E., Freudenthal, R., Romano, A., The IΚB kinase inhibitor sulfasalazine impairs long-term memory in the crab Chasmagnathus (2002) Neuroscience, 112, pp. 161-172
  • Misanin, J.R., Miller, R.R., Lewis, D.J., Retrograde amnesia produced by electroconvulsive shock following reactivation of a consolidated memory trace (1968) Science, 160, pp. 554-555
  • Müller, U., Prolonged activation of cAMP-dependent protein kinase during conditioning induces long-term memory in honeybees (2000) Neuron, 27, pp. 159-168
  • Nadel, L., Land, C., Memory traces revisited (2000) Nat Rev Neurosci, 1, pp. 209-212
  • Nader, K., Schafe, G.E., Le Doux, J.E., Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval (2000) Nature, 406, pp. 722-726
  • Pedreira, M.E., Dimant, B., Tomsic, D., Quesada-Allue, L.A., Maldonado, H., Cycloheximide inhibits context memory and long-term habituation in the crab Chasmagnathus (1995) Pharmacol Biochem Behav, 52, pp. 385-395
  • Pedreira, M.E., Dimant, B., Maldonado, H., Inhibitors of protein and RNA synthesis block context memory and long-term habituation in the crab Chasmagnathus (1996) Pharmacol Biochem Behav, 54, pp. 611-617
  • Peeke, H.V.S., Veno, A., Stimulus specificity of habituated aggression in the three-spined sticklebacks Gasterosteus acualeatus (1976) Z Tierpsychol, 40, pp. 53-58
  • Pereyra, P., Saraco, M., Maldonado, H., Decreased response or alternative defensive strategy in escape: Two different types of longterm memory in the crab Chasmagnathus (1999) J Comp Physiol, 184, pp. 301-310
  • Pereyra, P., Gonzalez Portino, E., Maldonado, H., Conditioned defensive freezing in the crab is context-specific but not triggered by the context (2000) Neurobiol Learn Mem, 74, pp. 119-134
  • Przybyslawski, J., Sara, S.J., Reconsolidation of memory after its reactivation (1997) Behav Brain Res, 84, pp. 241-246
  • Przybyslawski, J., Roulet, P., Sara, S.J., Attenuation of emotional and nonemotional memories after their reactivation: Role of β-adrenergic receptors (1999) J Neurosci, 19, pp. 6623-6628
  • Rescorla, D.A., Behavioral studies of pavlovian conditioning (1988) Annu Rev Neurosci, 1, pp. 320-352
  • Romano, A., Delorenzi, A., Pedreira, M.E., Tomsic, D., Maldonado, H., Acute administration of a permeant analog of cAMP and phosphodiesterase inhibitor improve long-term habituation in the crab Chasmagnathus (1996) Behav Brain Res, 75, pp. 119-125
  • Romano, A., Locatelli, F., Delorenzi, A., Pedreira, M.E., Maldonado, H., Effects of activation and inhibition of cAMP-dependent protein kinase on long-term habituation in the crab Chasmagnathus (1996) Brain Res, 735, pp. 131-140
  • Rosenthal, R., Rosnow, R.L., (1985) Contrast Analysis Focused Comparisons in the Analysis of Variance, , Cambridge, UK: Cambridge UP
  • Sara, S.J., Noradrenergic modulation of selective attention: Its role in memory retrieval (1985) Ann NY Acad Sci, 444, pp. 178-193
  • Sara, S.J., Retrieval and reconsolidation: Toward a neurobiology of remembering (2000) Learn Mem, 7, pp. 73-84
  • Sekiguchi, T., Yamada, A., Suzuki, H., Reactivation-dependent changes in memory states in the terrestrial slug Limax flavus (1997) Learn Mem, 4, pp. 356-364
  • Shimizu, E., Tang, Y.P., Rampon, C., Tsien, J.Z., NMDA receptordependent synaptic reinforcement as a crucial process for memory consolidation (2000) Science, 290, pp. 1170-1174
  • Spear, N.E., Mueller, C.W., Consolidation as a function of retrieval (1984) Memory Consolidation: Psychobiology of Cognition, , Weingartner H, Parker ES, eds. Hillsdale, NJ: Erlbaum
  • Steele, R.J., Morris, R.G.M., Delay-dependent impairment of a matching to place task with chronic intrahippocampal infusion of the NMDA antagonist D-AP5 (1999) Hippocampus, 9, pp. 118-136
  • Summers, M.J., Crowe, S.F., Ng, K.T., Administration of DL-2-amino-5-phosphonovaleric acid (AP5) induces transient inhibition of reminder-activated memory retrieval in day-old chicks (1997) Brain Res Cogn Brain Res, 5, pp. 311-321
  • Tomsic, D., Maldonado, H., Rakitin, A., Morphine and GABA: Effects on perception, escape response and long-term habituation to a danger stimulus in the crab Chasmagnathus (1991) Brain Res Bull, 26, pp. 694-706
  • Tomsic, D., Pedreira, M.E., Romano, A., Hermitte, G., Maldonado, H., Context-US association as a determinant of long-term habituation in the crab Chasmagnathus (1998) Anim Learn Behav, 26, pp. 196-204
  • Troncoso, J., Maldonado, H., Two related forms of memory in the crab Chasmagnathus are differentially affected by NMDA receptor antagonists (2002) Pharmacol Biochem Behav, 72, pp. 251-265
  • Tully, T., Toward a molecular biology of memory: The light's coming on! (1998) Nat Neurosci, 1, pp. 543-545
  • Tully, T., Preat, T., Boynton, S.C., Del Vecchio, M., Genetic dissection of consolidated memory in Drosophila (1994) Cell, 79, pp. 35-47

Citas:

---------- APA ----------
Pedreira, M.E., Pérez-Cuesta, L.M. & Maldonado, H. (2002) . Reactivation and reconsolidation of long-term memory in the crab Chasmagnathus: Protein synthesis requirement and mediation by NMDA-type glutamatergic receptors. Journal of Neuroscience, 22(18), 8305-8311.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_02706474_v22_n18_p8305_Pedreira [ ]
---------- CHICAGO ----------
Pedreira, M.E., Pérez-Cuesta, L.M., Maldonado, H. "Reactivation and reconsolidation of long-term memory in the crab Chasmagnathus: Protein synthesis requirement and mediation by NMDA-type glutamatergic receptors" . Journal of Neuroscience 22, no. 18 (2002) : 8305-8311.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_02706474_v22_n18_p8305_Pedreira [ ]
---------- MLA ----------
Pedreira, M.E., Pérez-Cuesta, L.M., Maldonado, H. "Reactivation and reconsolidation of long-term memory in the crab Chasmagnathus: Protein synthesis requirement and mediation by NMDA-type glutamatergic receptors" . Journal of Neuroscience, vol. 22, no. 18, 2002, pp. 8305-8311.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_02706474_v22_n18_p8305_Pedreira [ ]
---------- VANCOUVER ----------
Pedreira, M.E., Pérez-Cuesta, L.M., Maldonado, H. Reactivation and reconsolidation of long-term memory in the crab Chasmagnathus: Protein synthesis requirement and mediation by NMDA-type glutamatergic receptors. J. Neurosci. 2002;22(18):8305-8311.
Available from: https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_02706474_v22_n18_p8305_Pedreira [ ]