Abstract:
Following antigenic stimulation with specific (alloantigen) and non-specific (sheep red blood cells (SRBC) and lipopolysaccharide (LPS)) antigens the expression of β-adrenergic receptors and the interference of immune sera IgG, on uterine smooth muscle β-adrenoceptor-specific ligands were studied. The binding of alloimmune IgG to β-adrenoceptors appeared to be specific, because immunization with SRBC and LPS did not induce anti-β-adrenoceptors antibodies. On the contrary, the decrease in β-adrenergic receptor expression was observed even with alloantigens and with the conventional antigenic challenge, suggesting that this phenomenon could be a non-specific immunoregulatory mechanism. © 1989.
Registro:
Documento: |
Artículo
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Título: | Sympathetic control of specific and non-specific immune response |
Autor: | Sales, M.E.; Sterin-Borda, L.; Borda, E.S. |
Filiación: | Centro de Estudios Farmacológicos y de Principios Naturales (CEFAPRIN), CONICET. Serrano 665, 1414 Buenos Aires, Argentina
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Palabras clave: | beta adrenergic receptor; immunoglobulin g; animal cell; animal experiment; article; immune response; mouse; nonhuman; priority journal; Animal; Antigens; Binding, Competitive; Female; Immunization; Immunoglobulin G; In Vitro; Isoantibodies; Mice; Neuroimmunomodulation; Receptors, Adrenergic, beta; Support, Non-U.S. Gov't; Sympathetic Nervous System; Uterus |
Año: | 1989
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Volumen: | 11
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Número: | 8
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Página de inicio: | 947
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Página de fin: | 951
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DOI: |
http://dx.doi.org/10.1016/0192-0561(89)90117-3 |
Título revista: | International Journal of Immunopharmacology
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Título revista abreviado: | Int. J. Immunopharmacol.
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ISSN: | 01920561
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CODEN: | IJIMD
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CAS: | Antigens; Immunoglobulin G; Isoantibodies; Receptors, Adrenergic, beta
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01920561_v11_n8_p947_Sales |
Referencias:
- Andersson, Johansson, Salomonsson, time course of resensitization of rat uterine beta adrenoceptor system (1988) Pharmac. Toxic., 62, pp. 29-31
- Borda, Pascual, Cossio, Arana, Sterin-Borda, A circulating IgG in Chagas' disease which binds to beta adrenoceptors of myocardium and modulates their activity (1984) Clin. exp. Immun., 57, pp. 679-686
- Borda, Perez Leiros, Sterin-Borda, Role of beta 2 adrenoceptors in the biological effect of autoimmune orchitis spleen cells (1986) Can. J. Pharmac., 64, pp. 1091-1095
- Borda, Genaro, Cremaschi, Sales, Sterin-Borda, Beta adrenergic inhibitory effect of alloimmune antibody on isolated oviductal tract of mice (1984) Eur. J. Pharmac., 100, pp. 195-200
- Bracco, Finiasz, Cangiani, Borda, Sterin-Borda, Modification of the contractile activity of isolated rat atria by lectin-activated T lymphocyte subsets (1985) Cellular Immunology, 90, pp. 208-216
- Cremaschi, Sterin-Borda, Genaro, Borda, Braun, Pharmacologic effects on mouse isolated atria of immunoglobulins directed against class I histocompatibility antigens (1984) J. Immun., 133, pp. 2681-2685
- Cremaschi, Sterin-Borda, Biological effects and cyclic AMP production during molecular histocompatibility antigen and beta adrenoceptor interactions (1988) Int. J. Immunopharmac., , In Press
- Del Rey, Besedowsky, Sorkin, Prada, Bondiollotti, Sympathetic immunoregulation: difference between high and low responder animals (1982) Am. J. Physiol., 11, pp. R30-R33
- Genaro, Borda, Cremaschi, Sterin-Borda, Braun, H-2 specific inotropic effect of alloimmune lymphoid cells on mouse isolated atria (1986) Immunopharmacology, 11, pp. 129-140
- Perez Leiros, Sterin-Borda, Cossio, Bustuoabad, Borda, Potential role of mononuclear cells infiltration on the autoimmune myocardial dysfunction (1986) Clin Exp Immunol, 63, pp. 648-655
- Perez Leiros, Sterin-Borda, Borda, Lymphocytes infiltration induces dysfunction in autoimmune myocarditis role of SRS-A (1988) Journal of Molecular and Cellular Cardiology, 20, pp. 149-158
- Perez Leiros, Borda, Characterization of (3H)-DHA binding to intact mouse lymphocytes effect of experimental autoimmune orchitis on beta adrenoceptor expression (1985) International Journal of Immunopharmacology, 8, pp. 405-410
- Perez Leiros, Sterin-Borda, Borda, Beta adrenergic cardiac antibody in autoimmune myocarditis (1988) Autoimmunity, , In press
- Solano, Cremaschi, Sanchez, Borda, Sterin-Borda, Podesta, Molecular and biological interaction between major histocompatibility complex class I antigens and luteinizing hormone receptors or beta adrenergic receptors triggers cellular response in mice (1988) Proc. natn. Acad. Sci. U.S.A., , In press
- Sterin-Borda, Cantore, Pascual, Borda, Cossio, Arana, Passeron, Chagasic IgG binds and interacts with cardiac beta adrenoceptor-coupled adenylate cyclase system (1986) Int. J. Immunopharmac., 8, pp. 581-588
- Sterin-Borda, Cremaschi, Pascual, Genaro, Borda, Alloimmune IgG binds and modulates cardiac beta adrenoceptor activity (1984) Clin. exp. Immun., 58, pp. 223-228
Citas:
---------- APA ----------
Sales, M.E., Sterin-Borda, L. & Borda, E.S.
(1989)
. Sympathetic control of specific and non-specific immune response. International Journal of Immunopharmacology, 11(8), 947-951.
http://dx.doi.org/10.1016/0192-0561(89)90117-3---------- CHICAGO ----------
Sales, M.E., Sterin-Borda, L., Borda, E.S.
"Sympathetic control of specific and non-specific immune response"
. International Journal of Immunopharmacology 11, no. 8
(1989) : 947-951.
http://dx.doi.org/10.1016/0192-0561(89)90117-3---------- MLA ----------
Sales, M.E., Sterin-Borda, L., Borda, E.S.
"Sympathetic control of specific and non-specific immune response"
. International Journal of Immunopharmacology, vol. 11, no. 8, 1989, pp. 947-951.
http://dx.doi.org/10.1016/0192-0561(89)90117-3---------- VANCOUVER ----------
Sales, M.E., Sterin-Borda, L., Borda, E.S. Sympathetic control of specific and non-specific immune response. Int. J. Immunopharmacol. 1989;11(8):947-951.
http://dx.doi.org/10.1016/0192-0561(89)90117-3