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Abstract:

The effect of naturally occurring phenolic compounds on Aspergillus carbonarius growth and ochratoxin A (OTA) production was studied. Caffeic acid and the flavonoids, rutin and quercetin, were added to Czapek Yeast Extract agar at concentrations ranging between 50 and 500 mg/l. All phenolic compounds had a significant influence on growth rate and lag phase of A. carbonarius at 250 mg/l. The growth was completely inhibited with 500 mg/l. In comparison with the control, a significant decrease in OTA production was observed with all phenolic compounds. In general, effect on growth was less evident than effect on toxin production. An inhibitory effect on growth and OTA production, as concentration was increased was observed in all cases. The response of A. carbonarius to the flavonoids, rutin and quercetin, was similar. The inhibitory effect of these natural phenolic compounds on fungal growth and OTA production could be an alternative to the use of chemical fungicides. © 2009 Society for Mycotoxin Research and Springer.

Registro:

Documento: Artículo
Título:Inhibition of growth and ochratoxin A biosynthesis in Aspergillus carbonarius by flavonoid and nonflavonoid compounds
Autor:Romero, S.M.; Alberto, M.R.; Manca De Nadra, M.C.; Vaamonde, G.
Filiación:Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pab. II, 3o Piso, Buenos Aires 1428, Argentina
Instituto de Química Del Noroeste Argentino, INQUINOA, CONICET-CCT, Ayacucho 491, Tucumán 4000, Argentina
Centro de Referencia Para Lactobacilos (CERELA), Chacabuco 145, Tucumán 4000, Argentina
Palabras clave:Antifungal activity; Aspergillus carbonarius; Caffeic acid; Ochratoxin A; Quercetin; Rutin; caffeic acid; flavonoid; fungicide; ochratoxin; phenol derivative; quercetin; rutoside; article; Aspergillus; aspergillus carbonarius; biosynthesis; fungus growth; growth inhibition; growth rate; nonhuman; statistical analysis; toxin synthesis; yeast; Aspergillus carbonarius
Año:2009
Volumen:25
Número:3
Página de inicio:165
Página de fin:170
DOI: http://dx.doi.org/10.1007/s12550-009-0026-y
Título revista:Mycotoxin Research
Título revista abreviado:Mycotoxin Res.
ISSN:01787888
CAS:caffeic acid, 27323-69-9, 331-39-5; ochratoxin, 303-47-9, 37203-43-3; quercetin, 117-39-5; rutoside, 153-18-4, 22519-99-9
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01787888_v25_n3_p165_Romero

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Citas:

---------- APA ----------
Romero, S.M., Alberto, M.R., Manca De Nadra, M.C. & Vaamonde, G. (2009) . Inhibition of growth and ochratoxin A biosynthesis in Aspergillus carbonarius by flavonoid and nonflavonoid compounds. Mycotoxin Research, 25(3), 165-170.
http://dx.doi.org/10.1007/s12550-009-0026-y
---------- CHICAGO ----------
Romero, S.M., Alberto, M.R., Manca De Nadra, M.C., Vaamonde, G. "Inhibition of growth and ochratoxin A biosynthesis in Aspergillus carbonarius by flavonoid and nonflavonoid compounds" . Mycotoxin Research 25, no. 3 (2009) : 165-170.
http://dx.doi.org/10.1007/s12550-009-0026-y
---------- MLA ----------
Romero, S.M., Alberto, M.R., Manca De Nadra, M.C., Vaamonde, G. "Inhibition of growth and ochratoxin A biosynthesis in Aspergillus carbonarius by flavonoid and nonflavonoid compounds" . Mycotoxin Research, vol. 25, no. 3, 2009, pp. 165-170.
http://dx.doi.org/10.1007/s12550-009-0026-y
---------- VANCOUVER ----------
Romero, S.M., Alberto, M.R., Manca De Nadra, M.C., Vaamonde, G. Inhibition of growth and ochratoxin A biosynthesis in Aspergillus carbonarius by flavonoid and nonflavonoid compounds. Mycotoxin Res. 2009;25(3):165-170.
http://dx.doi.org/10.1007/s12550-009-0026-y