The capacity of antibodies in serum from individuals with chronic Chagas' disease to react with antigens in different subcellular fractions of Trypanosoma cruzi varied according to the clinical status of the patients. Antibodies in serum of asymptomatic patients were directed mostly against antigens in the cytosol of the parasite, whereas in overtly cardiopathic patients antibodies were directed mostly against antigens in the microsomal fractions.
Documento: | Artículo |
Título: | Chagas' disease: Humoral response to subcellular fraction of Trypanosoma cruzi in symptomatic and asymptomatic patients |
Autor: | De Titto, E.H.; Moreno, M.; Braun, M.; Segura, E.L. |
Filiación: | Centro de Estudios Farmacologicos y de Principios Naturales, Consejo Nacional de Investigaciones Cientificas y Tecnicas, Buenos Aires, Argentina |
Palabras clave: | parasite antigen; blood and hemopoietic system; cardiomyopathy; chagas disease; cytosol; heart; human; immune response; microsome; protozoon; serum; trypanosoma cruzi; Adult; Animal; Antibodies, Protozoan; Antibody Formation; Antigens, Protozoan; Chagas Disease; Enzyme-Linked Immunosorbent Assay; Human; Middle Age; Subcellular Fractions; Support, Non-U.S. Gov't; Trypanosoma cruzi |
Año: | 1987 |
Volumen: | 38 |
Número: | 3 |
Página de inicio: | 163 |
Página de fin: | 166 |
Título revista: | Tropical Medicine and Parasitology |
Título revista abreviado: | TROP. MED. PARASITOL. |
ISSN: | 01772392 |
CODEN: | TMPAE |
CAS: | Antibodies, Protozoan; Antigens, Protozoan |
Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01772392_v38_n3_p163_DeTitto |