Artículo

Canosa, L.F.; Pozzi, A.G.; Ceballos, N.R. "Pregnenolone and progesterone metabolism by the testes of Bufo arenarum" (1998) Journal of Comparative Physiology - B Biochemical, Systemic, and Environmental Physiology. 168(7):491-496
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Abstract:

Sliced testis tissue from Bufo arenarum was incubated in the presence of [3H]pregnenolone. Testis fragments were also used for double isotope experiments using [3H]pregnenolone and [14C]progesterone. Specific activities were equated with the addition of radioinert pregnenolone. When yields of radiometabolites were analysed, pregnenolone was found to be a good precursor for C19 steroids such as dehydroepiandrosterone, 5-androsten-3β,17β diol, testosterone, 5α-dihydrotestosterone and a C21 steroid, 5α-pregnan-3,20 dione. Progesterone mainly converts to 5α-pregnan-3,20 dione, asteroid with unknown function in amphibians. The 5-ene pathway, including 5-androsten-3β,17β diol as intermediate, could be predominant for androgen biosynthesis. Testes bypass not only progesterone but also androstenedione for testosterone biosynthesis.

Registro:

Documento: Artículo
Título:Pregnenolone and progesterone metabolism by the testes of Bufo arenarum
Autor:Canosa, L.F.; Pozzi, A.G.; Ceballos, N.R.
Filiación:Lab. de Endocrinol. Comparada, Depto. de Ciencias Biológicas, Ciudad Universitaria, Pabellón 2, 1428 Buenos Aires, Argentina
Palabras clave:Anura; Steroid hormones; Steroidogenesis; Testes; Toad; Bufo arenarum
Año:1998
Volumen:168
Número:7
Página de inicio:491
Página de fin:496
DOI: http://dx.doi.org/10.1007/s003600050169
Título revista:Journal of Comparative Physiology - B Biochemical, Systemic, and Environmental Physiology
Título revista abreviado:J. Comp. Physiol. B Biochem. Syst. Environ. Physiol.
ISSN:01741578
CODEN:JCPBD
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01741578_v168_n7_p491_Canosa

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Citas:

---------- APA ----------
Canosa, L.F., Pozzi, A.G. & Ceballos, N.R. (1998) . Pregnenolone and progesterone metabolism by the testes of Bufo arenarum. Journal of Comparative Physiology - B Biochemical, Systemic, and Environmental Physiology, 168(7), 491-496.
http://dx.doi.org/10.1007/s003600050169
---------- CHICAGO ----------
Canosa, L.F., Pozzi, A.G., Ceballos, N.R. "Pregnenolone and progesterone metabolism by the testes of Bufo arenarum" . Journal of Comparative Physiology - B Biochemical, Systemic, and Environmental Physiology 168, no. 7 (1998) : 491-496.
http://dx.doi.org/10.1007/s003600050169
---------- MLA ----------
Canosa, L.F., Pozzi, A.G., Ceballos, N.R. "Pregnenolone and progesterone metabolism by the testes of Bufo arenarum" . Journal of Comparative Physiology - B Biochemical, Systemic, and Environmental Physiology, vol. 168, no. 7, 1998, pp. 491-496.
http://dx.doi.org/10.1007/s003600050169
---------- VANCOUVER ----------
Canosa, L.F., Pozzi, A.G., Ceballos, N.R. Pregnenolone and progesterone metabolism by the testes of Bufo arenarum. J. Comp. Physiol. B Biochem. Syst. Environ. Physiol. 1998;168(7):491-496.
http://dx.doi.org/10.1007/s003600050169