Registro:

Referencias:

• Akama, K.T., McEwen, B.S., Estrogen stimulates postsynaptic density-95 rapid protein synthesis via the Akt/protein kinase B pathway (2003) J. Neurosci., 23 (6), pp. 2333-2339
• Altman, J., Postnatal development of the cerebellar cortex in the rat: II. Phases in the maturation of Purkinje cells and of the molecular layer (1972) J. Comp. Neurol., 145 (4), pp. 399-463
• Backman, S.A., Stambolic, V., Suzuki, A., Haight, J., Elia, A., Pretorius, J., Tsao, M.S., Mak, T.W., Deletion of PTEN in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease (2001) Nat. Genet., 29 (4), pp. 396-403
• Backman, S., Stambolic, V., Mak, T.W., PTEN function in mammalian cell size regulation (2002) Curr. Opin. Neurobiol., 12 (5), pp. 516-522. , (Review)
• Cantley, L.C., Neel, B.G., New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway (1999) Proc. Natl. Acad. Sci. U. S. A., 96 (8), pp. 4240-4245
• Cantrell, D.A., Phosphoinositide 3-kinase signaling pathways (2001) J. Cell. Sci., 114 (8), pp. 1439-1445. , Review
• (1995) Current Protocols in Immunology, 1. , J.E. Coligan, A.M. Kruisbeek, D.H. Margulies, E.M. Shevach, Strober W. New York: John Wiley & Sons. Section II Unit 2.4
• (1996) Proteins. Structures and Molecular Properties, p. 353. , T.E. Creighton. New York: W.H. Freeman and Company
• Di Cristofano, A., Pesce, B., Cordon-Cardo, C., Pandolfi, P.P., Pten is essential for embryonic development and tumour suppression (1998) Nat. Genet., 19 (4), pp. 348-355
• Gorlin, R.J., Cohen, M.M., Condon, L.M., Burke, B.A., Bannayan-Ruvalcaba syndrome (1992) Am. J. Med. Genet., 44, pp. 307-314
• Jiang, C., Schuman, E.M., Regulation and function of local protein synthesis in neuronal dendrites (2002) Trends Biochem. Sci., 27 (10), pp. 506-513
• Kimura, K., Hattori, S., Kabuyama, Y., Shizawa, Y., Takayanagi, J., Nakamura, S., Toki, S., Fukui, Y., Neurite outgrowth of PC12 cells is suppressed by Wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase (1994) J. Biol. Chem., 272, pp. 16089-16092
• Kwon, C.H., Zhu, X., Zhang, J., Knoop, L.L., Tharp, R., Smeyne, R.J., Eberhart, C.G., Baker, S.J., Pten regulates neuronal soma size: A mouse model of Lhermitte-Duclos disease (2001) Nat. Genet., 29 (4), pp. 404-411
• Lachyankar, M.B., Sultana, N., Schonhoff, C.M., Mitra, P., Poluha, W., Lambert, S., Quesenberry, P.J., Ross, A.H., A role for nuclear PTEN in neuronal differentiation (2000) J. Neurosci., 20 (4), pp. 1404-1413
• Landis, D.M., Sidman, R.L., Electron microscopic analysis of postnatal histogenesis in the cerebellar cortex of staggerer mutant mice (1978) J. Comp. Neurol., 179 (4), pp. 831-863
• Lee, J.O., Yang, H., Georgescu, M.M., Di Cristofano, A., Maehama, T., Shi, Y., Dixon, J.E., Pavletich, N.P., Crystal structure of the PTEN tumor suppressor: Implications for its phosphoinositide phosphatase activity and membrane association (1999) Cell, 99 (3), pp. 323-334
• Li, D.M., Sun, H., TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta (1997) Cancer Res., 57 (11), pp. 2124-2149
• Maheama, T., Dixon, J.E., The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate (1998) J. Biol. Chem., 273, pp. 13375-13378
• Marino, S., Krimpenfort, P., Leung, C., Van Der Korput, H.A., Trapman, J., Camenisch, I., Berns, A., Brandner, S., PTEN is essential for cell migration but not for fate determination and tumorigenesis in the cerebellum (2002) Development, 129 (14), pp. 3513-3522
• Markus, A., Zhong, J., Snider, W.D., Raf and akt mediate distinct aspects of sensory axon growth (2002) Neuron, 35 (1), pp. 65-76
• Mills, G.B., Lu, Y., Kohn, E.C., Linking molecular therapeutics to molecular diagnostics: Inhibition of the FRAP/RAFT/TOR component of the PI3K pathway preferentially blocks PTEN mutant cells in vitro and in vivo (2001) Proc. Natl. Acad. Sci. U. S. A., 98 (18), pp. 10031-10033. , (Comment on: Proc. Natl. Acad. Sci. U. S. A. 2001 98 (18) 10314-9 and 10320-5)
• Mizumori, S.J., Ragozzino, K.E., Cooper, B.G., Leutgeb, S., Hippocampal representational organization and spatial context (1999) Hippocampus, 9 (4), pp. 444-451
• Namikawa, K., Honma, M., Abe, K., Takeda, M., Mansur, K., Obata, T., Miwa, A., Kiyama, H., Akt/protein kinase B prevents injury-induced motoneuron death and accelerates axonal regeneration (2000) J. Neurosci., 20 (8), pp. 2875-2886
• Neshat, M.S., Mellinghoff, I.K., Tran, C., Stiles, B., Thomas, G., Petersen, R., Frost, P., Sawyers, C.L., Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR (2001) Proc. Natl. Acad. Sci. U. S. A., 98 (18), pp. 10314-10319
• Ostroff, L.E., Fiala, J.C., Allwardt, B., Harris, K.M., Polyribosomes redistribute from dendritic shafts into spines with enlarged synapses during LTP in developing rat hippocampal slices (2002) Neuron, 35 (3), pp. 535-545
• Patil, N., Cox, D.R., Bhat, D., Faham, M., Myers, R.M., Peterson, A.S., A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation (1995) Nat. Genet., 11 (2), pp. 126-129
• Podsypanina, K., Lee, R.T., Politis, C., Hennessy, I., Crane, A., Puc, J., Neshat, M., Parsons, R., An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice (2001) Proc. Natl. Acad. Sci. U. S. A., 98 (18), pp. 10320-10325
• Radrizzani, M., Carminatti, H., Pivetta, O.H., Idoyaga-Vargas, V.P., Developmental regulation of Thy 1.2 rate of synthesis in the mouse cerebellum (1995) J. Neurosci. Res., 42, pp. 220-227
• Raught, B., Gingras, A.C., Sonenberg, N., The target of rapamycin (TOR) proteins (2001) Proc. Natl. Acad. Sci. U. S. A., 98 (13), pp. 7037-7044. , Colloquium
• Rossi, P., De Filippi, G., Armano, S., Taglietti, V., D'Angelo, E., The weaver mutation causes a loss of inward rectifier current regulation in premigratory granule cells of the mouse cerebellum (1998) J. Neurosci., 18 (10), pp. 3537-3547
• (1989) Molecular Cloning: A Laboratory Manual, 3. , J. Sambrook, E.F. Fritsch, Maniatis T. 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press. Chap. 18
• Shi, S.H., Jan, L.Y., Jan, Y.N., Hippocampal neuronal polarity specified by spatially localized mPar3/mPar6 and PI 3-kinase activity (2003) Cell, 112 (1), pp. 63-75
• Sidman, R.L., Lane, P.W., Dickie, M.M., Staggerer, a new mutation in the mouse affecting the cerebellum (1962) Science, 137, pp. 610-612
• Smeyne, R.J., Goldowitz, D., Development and death of external granular layer cells in the weaver mouse cerebellum: A quantitative study (1989) J. Neurosci., 9 (5), pp. 1608-1620
• Sotelo, C., Anatomical, physiological and biochemical studies of the cerebellum from mutant mice. II. Morphological study of cerebellar cortical neurons and circuits in the weaver mouse (1975) Brain Res., 94 (1), pp. 19-44
• Stambolic, V., Suzuki, A., De La Pompa, J.L., Brothers, G.M., Mirtsos, C., Sasaki, T., Ruland, J., Mak, T.W., Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN (1998) Cell, 95 (1), pp. 29-39
• Stocker, H., Andjelkovic, M., Oldham, S., Laffargue, M., Wymann, M.P., Hemmings, B.A., Hafen, E., Living with lethal PIP3 levels: Viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB (2002) Science, 295 (5562), pp. 2088-2091
• Whitford, K.L., Dijkhuizen, P., Polleux, F., Ghosh, A., Molecular control of cortical dendrite development (2002) Annu. Rev. Neurosci., 25, pp. 127-149

Citas:

---------- APA ----------

---------- CHICAGO ----------

---------- MLA ----------

---------- VANCOUVER ----------