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Abstract:

Amino-acid starvation in polyamine-auxotrophic bacteria grown in the presence of putrescine provokes a marked inhibition of protein synthesis. This inhibition is almost completely relieved in polyamine-depleted cells. The differential behaviour of bacterial protein synthesis depending on the endogenous levels of polyamines is not due to a change in the uptake of amino acids used to measure protein synthesis, nor to the decreased growth rate of polyamine-depleted cells. During leucine starvation, cells grown with putrescine synthesized a somewhat lower amount of high-molecular-weight proteins than polyamine-depleted bacteria. In addition, cells with normal endogenous levels of polyamines accumulated significant amounts of 62 and 41 kDa polypeptides as well as several low-molecular-weight peptides. © 1988.

Registro:

Documento: Artículo
Título:Protein synthesis in polyamine-deficient bacteria during amino-acid starvation
Autor:Nastri, H.G.; Algranati, I.D.
Filiación:Instituto de Investigaciones Bioquimicas 'Fundacion Campomar', Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
Palabras clave:(E. coli); Amino acid starvation; Polyamide auxotrophy; Translation; amino acid; bacterial protein; polyamine; putrescine; article; biosynthesis; drug effect; Escherichia coli; genetics; kinetics; metabolism; molecular weight; transport at the cellular level; Amino Acids; Bacterial Proteins; Biological Transport; Escherichia coli; Kinetics; Molecular Weight; Polyamines; Putrescine; Support, Non-U.S. Gov't
Año:1988
Volumen:949
Número:1
Página de inicio:65
Página de fin:70
DOI: http://dx.doi.org/10.1016/0167-4781(88)90055-3
Título revista:BBA - Gene Structure and Expression
Título revista abreviado:Biochim. Biophys. Acta Gene Struct. Expr.
ISSN:01674781
CODEN:BBGSD
CAS:amino acid, 65072-01-7; putrescine, 110-60-1, 333-93-7; Amino Acids; Bacterial Proteins; Polyamines; Putrescine, 110-60-1
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01674781_v949_n1_p65_Nastri

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Citas:

---------- APA ----------
Nastri, H.G. & Algranati, I.D. (1988) . Protein synthesis in polyamine-deficient bacteria during amino-acid starvation. BBA - Gene Structure and Expression, 949(1), 65-70.
http://dx.doi.org/10.1016/0167-4781(88)90055-3
---------- CHICAGO ----------
Nastri, H.G., Algranati, I.D. "Protein synthesis in polyamine-deficient bacteria during amino-acid starvation" . BBA - Gene Structure and Expression 949, no. 1 (1988) : 65-70.
http://dx.doi.org/10.1016/0167-4781(88)90055-3
---------- MLA ----------
Nastri, H.G., Algranati, I.D. "Protein synthesis in polyamine-deficient bacteria during amino-acid starvation" . BBA - Gene Structure and Expression, vol. 949, no. 1, 1988, pp. 65-70.
http://dx.doi.org/10.1016/0167-4781(88)90055-3
---------- VANCOUVER ----------
Nastri, H.G., Algranati, I.D. Protein synthesis in polyamine-deficient bacteria during amino-acid starvation. Biochim. Biophys. Acta Gene Struct. Expr. 1988;949(1):65-70.
http://dx.doi.org/10.1016/0167-4781(88)90055-3