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Abstract:

Progesterone, produced by the ovaries and adrenal glands, regulates reproductive behavior and the surge of luteinizing hormone which precedes ovulation by acting on neurons located in different parts of the hypothalamus. The study of the activation of these reproductive functions in female rats has allowed to explore the different mechanisms of progesterone action in the brain. It has allowed to demonstrate that new actions of the hormone, which have been observed in particular in vitro systems, are also operational in vivo, and may thus be biologically relevant. This mainly concerns the direct actions of progesterone on receptors of neurotransmitters such as oxytocin and GABA. Activation of the progesterone receptor in the absence of ligand by phosphorylation may also play a role. Copyright (C) 1999 Elsevier Science B.V.

Registro:

Documento: Artículo
Título:Genomic and membrane actions of progesterone: Implications for reproductive physiology and behavior
Autor:Schumacher, M.; Coirini, H.; Robert, F.; Guennoun, R.; El-Etr, M.
Filiación:INSERM U488, 80 R. du Gen. Leclerc, 94276 Cedex, Le Kremlin-Bicêtre, France
Inst. Biologia Y Medicina Exp., 2490 V de Obligado, 1428, Buenos Aires, Argentina
Palabras clave:GABA; Gonadotropins; GT1 cells; LH; LHRH; Lordosis; Oxytocin; Progesterone; 4 aminobutyric acid; anxiolytic agent; bicuculline; corticotropin; dactinomycin; deoxycorticosterone; dopamine receptor; estrogen receptor; gonadorelin; membrane receptor; mifepristone; mineralocorticoid receptor; neuropeptide; neurosteroid; neurotensin; okadaic acid; oxytocin; oxytocin receptor; pregnenolone sulfate; progesterone; progesterone receptor; steroid receptor; substance P; trilostane; vinblastine; estrus; genetic transcription; hormone responsive element; hypothalamus; lordosis; luteinizing hormone release; nonhuman; priority journal; promoter region; reproduction; review; sexual behavior; signal transduction
Año:1999
Volumen:105
Número:1
Página de inicio:37
Página de fin:52
DOI: http://dx.doi.org/10.1016/S0166-4328(99)00081-9
Título revista:Behavioural Brain Research
Título revista abreviado:Behav. Brain Res.
ISSN:01664328
CODEN:BBRED
CAS:4 aminobutyric acid, 28805-76-7, 56-12-2; bicuculline, 485-49-4; corticotropin, 11136-52-0, 9002-60-2, 9061-27-2; dactinomycin, 1402-38-6, 1402-58-0, 50-76-0; deoxycorticosterone, 64-85-7; gonadorelin, 33515-09-2, 9034-40-6; mifepristone, 84371-65-3; neurotensin, 39379-15-2; okadaic acid, 78111-17-8; oxytocin, 50-56-6, 54577-94-5; pregnenolone sulfate, 1247-64-9; progesterone, 57-83-0; substance P, 33507-63-0; trilostane, 13647-35-3; vinblastine, 865-21-4
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01664328_v105_n1_p37_Schumacher

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Citas:

---------- APA ----------
Schumacher, M., Coirini, H., Robert, F., Guennoun, R. & El-Etr, M. (1999) . Genomic and membrane actions of progesterone: Implications for reproductive physiology and behavior. Behavioural Brain Research, 105(1), 37-52.
http://dx.doi.org/10.1016/S0166-4328(99)00081-9
---------- CHICAGO ----------
Schumacher, M., Coirini, H., Robert, F., Guennoun, R., El-Etr, M. "Genomic and membrane actions of progesterone: Implications for reproductive physiology and behavior" . Behavioural Brain Research 105, no. 1 (1999) : 37-52.
http://dx.doi.org/10.1016/S0166-4328(99)00081-9
---------- MLA ----------
Schumacher, M., Coirini, H., Robert, F., Guennoun, R., El-Etr, M. "Genomic and membrane actions of progesterone: Implications for reproductive physiology and behavior" . Behavioural Brain Research, vol. 105, no. 1, 1999, pp. 37-52.
http://dx.doi.org/10.1016/S0166-4328(99)00081-9
---------- VANCOUVER ----------
Schumacher, M., Coirini, H., Robert, F., Guennoun, R., El-Etr, M. Genomic and membrane actions of progesterone: Implications for reproductive physiology and behavior. Behav. Brain Res. 1999;105(1):37-52.
http://dx.doi.org/10.1016/S0166-4328(99)00081-9