Artículo
Nicotra, V.E.; Gil, R.R.; Vaccarini, C.; Oberti, J.C.; Burton, G. "15,21-Cyclowithanolides from Jaborosa bergii" (2003) Journal of Natural Products. 66(11):1471-1475
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Abstract:
Six new withanolides (1-6) were isolated from the aerial parts of Jaborosa bergii plants and characterized by spectroscopic methods (1D and 2D NMR, MS). Five of the new compounds presented a novel norbornane-type structure in ring D of the steroid nucleus (1-5), resulting from a carbon-carbon bond between C-15 and C-21. The sixth withanolide isolated was the 5α-chloro-6β -hydroxy analogue (6) of 2,3-dehydrojaborosalactol M (7), previously isolated from this plant. Compound 1 showed selective phytotoxicity toward monocotiledoneous and dicotiledoneous species.
Registro:
| Documento: | Artículo |
| Título: | 15,21-Cyclowithanolides from Jaborosa bergii |
| Autor: | Nicotra, V.E.; Gil, R.R.; Vaccarini, C.; Oberti, J.C.; Burton, G. |
| Filiación: | Departamento de Quimica Organica, Facultad de Ciencias Químicas, Universidad Nacional de Cordoba, 5000 Córdoba, Argentina Departamento de Quimica Organica, Fac. de Ciencias Exactas y Naturales, Universidad de Buenos Aires, C1428EGA Buenos Aires, Argentina Department of Chemistry, Carnegie Mellon University, 4400 Fifth Ave., Pittsburgh, PA 15213, United States |
| Palabras clave: | 15,21 cyclowithanolide derivative; 2,3 dehydrojaborosalactol; drug derivative; ergosterol; lactone derivative; phytosterol; unclassified drug; withanolide; angiosperm; Argentina; article; carbon nuclear magnetic resonance; chemical structure; chemistry; dose response; drug isolation; higher plant; isolation and purification; Jaborosa bergii; medicinal plant; nonhuman; nuclear magnetic resonance; phytochemistry; phytotoxicity; stereoisomerism; sterol analysis; Argentina; Dose-Response Relationship, Drug; Ergosterol; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plants, Medicinal; Solanaceae; Stereoisomerism; Embryophyta; Jaborosa; Magnoliophyta |
| Año: | 2003 |
| Volumen: | 66 |
| Número: | 11 |
| Página de inicio: | 1471 |
| Página de fin: | 1475 |
| Título revista: | Journal of Natural Products |
| Título revista abreviado: | J. Nat. Prod. |
| ISSN: | 01633864 |
| CODEN: | JNPRD |
| CAS: | ergosterol, 23637-22-1, 2418-45-3, 3992-98-1, 57-87-4; withanolide, 40326-62-3; Ergosterol, 57-87-4 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v66_n11_p1471_Nicotra |
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Citas:
---------- APA ----------
Nicotra, V.E., Gil, R.R., Vaccarini, C., Oberti, J.C. & Burton, G. (2003) . 15,21-Cyclowithanolides from Jaborosa bergii. Journal of Natural Products, 66(11), 1471-1475.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v66_n11_p1471_Nicotra [ ]
---------- CHICAGO ----------
Nicotra, V.E., Gil, R.R., Vaccarini, C., Oberti, J.C., Burton, G. "15,21-Cyclowithanolides from Jaborosa bergii" . Journal of Natural Products 66, no. 11 (2003) : 1471-1475.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v66_n11_p1471_Nicotra [ ]
---------- MLA ----------
Nicotra, V.E., Gil, R.R., Vaccarini, C., Oberti, J.C., Burton, G. "15,21-Cyclowithanolides from Jaborosa bergii" . Journal of Natural Products, vol. 66, no. 11, 2003, pp. 1471-1475.Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v66_n11_p1471_Nicotra [ ]
---------- VANCOUVER ----------
Nicotra, V.E., Gil, R.R., Vaccarini, C., Oberti, J.C., Burton, G. 15,21-Cyclowithanolides from Jaborosa bergii. J. Nat. Prod. 2003;66(11):1471-1475.Available from: https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v66_n11_p1471_Nicotra [ ]
