Abstract:
Five new withanolides, 5α,6α:22,26:24,25-triepoxy-16α,26-dihydroxy-18 (13→17)-abeo-ergosta-2,13-dien-1-one (salpichrolide N, 1), 5α,6α:22,26:24,25-triepoxi-15α,26-dihydroxyergosta-2, 16-dien-1-one (salpichrolide L, 2), 5α,6α:22,26-diepoxi-24,25,26-trihydroxy-17(13→18)- abeo-ergosta-2,13,15,17-tetraen-1-one (salpichrolide M, 3a), 5α,6α:22,25:22,26-triepoxy-24-hydroxy-17(13→18)- abeo-ergosta-2,13,15,17-tetraen-1-one (salpichrolide J, 4), and 5α,6α:22,26-diepoxy-22,24,25-trihydroxy-17(13→18)- abeo-ergosta-2,13,15,17-tetraen-1-one (salpichrolide K, 5), were isolated from the leaves of Salpichroa origanifolia and characterized by a combination of spectroscopic (1D and 2D NMR, MS) and chemical methods.
Registro:
Documento: |
Artículo
|
Título: | Withanolides from Salpichroa origanifolia |
Autor: | Tettamanzi, M.C.; Veleiro, A.S.; De la Fuente, J.R.; Burton, G. |
Filiación: | Departamento de Quimica Organica, Facultad Ciencias Exactas Naturales, Universidad de Buenos Aires, Pabellón 2, (1428)Buenos Aires, Argentina Consejo de Investigación, Universidad Nacional de Salta, (4400)Salta, Argentina
|
Palabras clave: | phytosterol; salpichrolide j; salpichrolide k; salpichrolide l; salpichrolide m; salpichrolide n; unclassified drug; withanolide; article; chemical analysis; chemical structure; mass spectrometry; medicinal plant; molecular model; nonhuman; nuclear magnetic resonance spectroscopy; plant leaf; Salpichroa origanifolia; Argentina; Ergosterol; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plants, Medicinal |
Año: | 2001
|
Volumen: | 64
|
Número: | 6
|
Página de inicio: | 783
|
Página de fin: | 786
|
DOI: |
http://dx.doi.org/10.1021/np010010t |
Título revista: | Journal of Natural Products
|
Título revista abreviado: | J. Nat. Prod.
|
ISSN: | 01633864
|
CODEN: | JNPRD
|
CAS: | withanolide, 40326-62-3; Ergosterol, 57-87-4
|
Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v64_n6_p783_Tettamanzi |
Referencias:
- (2000) 12th National Symposium of Organic Chemistry (XII SINAQO), Córdoba, Argentina, November 1999, 5, pp. 449-450. , Abstract published in Molecules [online computer file]
- Ray, A.B., Gupta, M., (1994) Prog. Chem. Org. Nat. Prod., 63, pp. 1-106
- Veleiro, A.S., Oberti, J.C., Burton, G., (1992) Phytochemistry, 31, pp. 935-937
- Veleiro, A.S., Burton, G., Bonetto, G.M., Gil, R.R., Oberti, J.C., (1994) J. Nat. Prod., 57, pp. 1741-1745
- Tettamanzi, M.C., Veleiro, A.S., Oberti, J.C., Burton, G., (1996) Phytochemistry, 43, pp. 461-463
- Tettamanzi, M.C., Veleiro, A.S., Oberti, J.C., Burton, G., (1998) J. Nat. Prod., 61, pp. 338-342
- Mareggiani, G., Picollo, M.I., Zerba, E., Burton, G., Tettamanzi, M.C., Benedetti-Doctorovich, M.O.V., Veleiro, A.S., (2000) J. Nat. Prod., 63, pp. 1113-1116
- Shingu, K., Marubayashi, N., Ueda, I., Yahara, S., Nohara, T., (1990) Chem. Pharm. Bull., 38, pp. 1107-1109
- Gill, H.K., Smith, R.W., Whiting, D.A., (1990) J. Chem. Soc., Perkin Trans., 1, pp. 2989-2993
- Shingu, K., Yahara, S., Nohara, T., (1994) Chem. Pharm. Bull., 42, pp. 318-321
- Kirson, J., Gottlieb, H., Glotter, E., (1980) J. Chem. Res, Synop., 125
- (1980) J. Chem. Res., Miniprint, pp. 2134-2156
Citas:
---------- APA ----------
Tettamanzi, M.C., Veleiro, A.S., De la Fuente, J.R. & Burton, G.
(2001)
. Withanolides from Salpichroa origanifolia. Journal of Natural Products, 64(6), 783-786.
http://dx.doi.org/10.1021/np010010t---------- CHICAGO ----------
Tettamanzi, M.C., Veleiro, A.S., De la Fuente, J.R., Burton, G.
"Withanolides from Salpichroa origanifolia"
. Journal of Natural Products 64, no. 6
(2001) : 783-786.
http://dx.doi.org/10.1021/np010010t---------- MLA ----------
Tettamanzi, M.C., Veleiro, A.S., De la Fuente, J.R., Burton, G.
"Withanolides from Salpichroa origanifolia"
. Journal of Natural Products, vol. 64, no. 6, 2001, pp. 783-786.
http://dx.doi.org/10.1021/np010010t---------- VANCOUVER ----------
Tettamanzi, M.C., Veleiro, A.S., De la Fuente, J.R., Burton, G. Withanolides from Salpichroa origanifolia. J. Nat. Prod. 2001;64(6):783-786.
http://dx.doi.org/10.1021/np010010t