Artículo
Silva, G.L.; Burton, G.; Oberti, J.C. "18,20-Hemiacetal-type and other withanolides from Dunalia brachyacantha" (1999) Journal of Natural Products. 62(7):949-953
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Abstract:
Two Dunalia brachyacantha specimens collected at different locations in Argentina were investigated separately. The 18,20-hemiacetal-type withanolides (17S,20R,22R,24S,25R)-4β-acetyloxy-5β,6β:18,20-diepoxy-18- hydroxy-1-oxowitha-2-enolide (1) and (17S,20R,22R)-4β-acetyloxy- 5β,6β:18,20-diepoxy-18-hydroxy-1-oxowitha-2,24-dienolide (2) were isolated from the first collection, both as mixtures epimeric at C-18. The second collection contained instead (17R,20S,22R)-5β,6β-epoxy-4β,16α-dihydroxy- 1-oxowitha-2,24-dienolide (3); (17R,20S,22R)-5β,6β-epoxy-4β,18-dihydroxy- 1-oxowitha-2,24-dienolide (4), and (17R,20S,22R)-5β,6β-epoxy-4β,16α- dihydroxy-1,18-dioxowitha-2,24-dienolide (5). All five new withanolides (15) bear an A and B ring substitution pattern similar to that of withaferin A, and their structural elucidation was achieved by spectroscopic techniques.
Registro:
| Documento: | Artículo |
| Título: | 18,20-Hemiacetal-type and other withanolides from Dunalia brachyacantha |
| Autor: | Silva, G.L.; Burton, G.; Oberti, J.C. |
| Filiación: | Depto. de Quimica Organica, Facultad de Ciencias Químicas, Ciudad Universitaria, 5000 Córdoba, Argentina Depto. de Quimica Organica, Fac. de Ciencias Exactas y Naturales, Ciudad Universitaria, 1428 Buenos Aires, Argentina |
| Palabras clave: | plant extract; withanolide; Argentina; article; chemical analysis; chemical structure; plant; plant leaf; spectroscopy; Dunalia brachyacantha |
| Año: | 1999 |
| Volumen: | 62 |
| Número: | 7 |
| Página de inicio: | 949 |
| Página de fin: | 953 |
| DOI: | http://dx.doi.org/10.1021/np9804536 |
| Título revista: | Journal of Natural Products |
| Título revista abreviado: | J. Nat. Prod. |
| ISSN: | 01633864 |
| CODEN: | JNPRD |
| CAS: | withanolide, 40326-62-3 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v62_n7_p949_Silva |
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Citas:
---------- APA ----------
Silva, G.L., Burton, G. & Oberti, J.C. (1999) . 18,20-Hemiacetal-type and other withanolides from Dunalia brachyacantha. Journal of Natural Products, 62(7), 949-953.http://dx.doi.org/10.1021/np9804536
---------- CHICAGO ----------
Silva, G.L., Burton, G., Oberti, J.C. "18,20-Hemiacetal-type and other withanolides from Dunalia brachyacantha" . Journal of Natural Products 62, no. 7 (1999) : 949-953.http://dx.doi.org/10.1021/np9804536
---------- MLA ----------
Silva, G.L., Burton, G., Oberti, J.C. "18,20-Hemiacetal-type and other withanolides from Dunalia brachyacantha" . Journal of Natural Products, vol. 62, no. 7, 1999, pp. 949-953.http://dx.doi.org/10.1021/np9804536
---------- VANCOUVER ----------
Silva, G.L., Burton, G., Oberti, J.C. 18,20-Hemiacetal-type and other withanolides from Dunalia brachyacantha. J. Nat. Prod. 1999;62(7):949-953.http://dx.doi.org/10.1021/np9804536
