Artículo
Veleiro, A.S.; Cirigliano, A.M.; Oberti, J.C.; Burton, G. "7-Hydroxywithanolides from Datura ferox" (1999) Journal of Natural Products. 62(7):1010-1012
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Abstract:
Three new withanolides were isolated from leaves of Datura ferox. Their structures were established as (17R,20S,22R)-5α,6α,7β,12α-tetrahydroxy- 1-oxowitha-2,24-dienolide (1), (17R,20S,22R,24S,25S)-24,25-epoxy- 5α,6α,7β,12α-tetrahydroxy-1-oxowitha-2-enolide (2), and (17R,20S,22R)- 5α,6α-epoxy-7α-hydroxy-1,12-dioxowitha-2,24-dienolide (3), using spectroscopic methods (NMR, MS) and molecular modeling.
Registro:
| Documento: | Artículo |
| Título: | 7-Hydroxywithanolides from Datura ferox |
| Autor: | Veleiro, A.S.; Cirigliano, A.M.; Oberti, J.C.; Burton, G. |
| Filiación: | Depto. de Quimica Organica, Fac. de Ciencias Exactas y Naturales, Ciudad Universitaria, (1428) Buenos Aires, Argentina Depto. de Quimica Organica, Facultad de Ciencias Químicas, Univ. Nacional de Córdoba, Casilla 61, 500 Córdoba, Argentina |
| Palabras clave: | withanolide; article; drug isolation; drug structure; mass spectrometry; molecular model; nonhuman; nuclear magnetic resonance; plant leaf; Datura ferox |
| Año: | 1999 |
| Volumen: | 62 |
| Número: | 7 |
| Página de inicio: | 1010 |
| Página de fin: | 1012 |
| DOI: | http://dx.doi.org/10.1021/np980320k |
| Título revista: | Journal of Natural Products |
| Título revista abreviado: | J. Nat. Prod. |
| ISSN: | 01633864 |
| CODEN: | JNPRD |
| CAS: | withanolide, 40326-62-3 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v62_n7_p1010_Veleiro |
Referencias:
- Ray, A.B., Gupta, M., (1994) Prog. Chem. Org. Nat. Prod., 63, pp. 1-106
- Baumann, T.W., Meier, C.M., (1993) Phytochemistry, 33, pp. 317-321
- Cirigliano, A.M., Veleiro, A.S., Oberti, J.C., Burton, G., (1995) Phytochemistry, 40, pp. 611-613
- Evans, W.C., Grout, R.J., Mensah, M.L.K., (1984) Phytochemistry, 23, pp. 1717-1720
- Kalla, A.K., Raina M, L., Dhar, K.L., Qurishi, M.A., Snatzke, G., (1979) Phytochemistry, 18, pp. 637-640
- Besalle, R., Lavie, D., Frolow, F., (1987) Phytochemistry, 26, pp. 1797-1800
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Citas:
---------- APA ----------
Veleiro, A.S., Cirigliano, A.M., Oberti, J.C. & Burton, G. (1999) . 7-Hydroxywithanolides from Datura ferox. Journal of Natural Products, 62(7), 1010-1012.http://dx.doi.org/10.1021/np980320k
---------- CHICAGO ----------
Veleiro, A.S., Cirigliano, A.M., Oberti, J.C., Burton, G. "7-Hydroxywithanolides from Datura ferox" . Journal of Natural Products 62, no. 7 (1999) : 1010-1012.http://dx.doi.org/10.1021/np980320k
---------- MLA ----------
Veleiro, A.S., Cirigliano, A.M., Oberti, J.C., Burton, G. "7-Hydroxywithanolides from Datura ferox" . Journal of Natural Products, vol. 62, no. 7, 1999, pp. 1010-1012.http://dx.doi.org/10.1021/np980320k
---------- VANCOUVER ----------
Veleiro, A.S., Cirigliano, A.M., Oberti, J.C., Burton, G. 7-Hydroxywithanolides from Datura ferox. J. Nat. Prod. 1999;62(7):1010-1012.http://dx.doi.org/10.1021/np980320k
