Artículo
Palermo, J.A.; Brasco, M.F.R.; Cabezas, E.; Balzaretti, V.; Seldes, A.M. "Celenamide E, a tripeptide alkaloid from the Patagonian sponge Cliona chilensis" (1998) Journal of Natural Products. 61(4):488-490
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Abstract:
Celenamide E, a novel tripeptide alkaloid and a possible biosynthetic precursor of the previously reported celenamides A-C, was isolated from the Patagonian sponge Cliona chilensis collected at Rada Tilly, Chubut, Argentina. The structure of celenamide E was elucidated by spectroscopic techniques-UV, IR, 1D and 2D NMR (COSY, NOESY, HETCOR, COLOC) experiments - HIRFABMS, and preparation of an hexaacetate derivative. An unusual feature of celenamide E is the presence of a N-terminal dehydroamino acid. Celenamide E shows antibiotic activity against Gram-positive bacteria at 50 μg/disk.
Registro:
| Documento: | Artículo |
| Título: | Celenamide E, a tripeptide alkaloid from the Patagonian sponge Cliona chilensis |
| Autor: | Palermo, J.A.; Brasco, M.F.R.; Cabezas, E.; Balzaretti, V.; Seldes, A.M. |
| Filiación: | Departamento de Quimica Organica, Facultad Ciencias Exactas Naturales, Universidad de Buenos Aires, Buenos Aires 1428, Argentina |
| Palabras clave: | alkaloid; celenamide e; unclassified drug; antibacterial activity; article; drug isolation; drug structure; gram positive bacterium; infrared spectroscopy; nonhuman; nuclear magnetic resonance; sponge (porifera); ultraviolet spectroscopy |
| Año: | 1998 |
| Volumen: | 61 |
| Número: | 4 |
| Página de inicio: | 488 |
| Página de fin: | 490 |
| DOI: | http://dx.doi.org/10.1021/np9701945 |
| Título revista: | Journal of Natural Products |
| Título revista abreviado: | J. Nat. Prod. |
| ISSN: | 01633864 |
| CODEN: | JNPRD |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v61_n4_p488_Palermo |
Citas:
---------- APA ----------
Palermo, J.A., Brasco, M.F.R., Cabezas, E., Balzaretti, V. & Seldes, A.M. (1998) . Celenamide E, a tripeptide alkaloid from the Patagonian sponge Cliona chilensis. Journal of Natural Products, 61(4), 488-490.http://dx.doi.org/10.1021/np9701945
---------- CHICAGO ----------
Palermo, J.A., Brasco, M.F.R., Cabezas, E., Balzaretti, V., Seldes, A.M. "Celenamide E, a tripeptide alkaloid from the Patagonian sponge Cliona chilensis" . Journal of Natural Products 61, no. 4 (1998) : 488-490.http://dx.doi.org/10.1021/np9701945
---------- MLA ----------
Palermo, J.A., Brasco, M.F.R., Cabezas, E., Balzaretti, V., Seldes, A.M. "Celenamide E, a tripeptide alkaloid from the Patagonian sponge Cliona chilensis" . Journal of Natural Products, vol. 61, no. 4, 1998, pp. 488-490.http://dx.doi.org/10.1021/np9701945
---------- VANCOUVER ----------
Palermo, J.A., Brasco, M.F.R., Cabezas, E., Balzaretti, V., Seldes, A.M. Celenamide E, a tripeptide alkaloid from the Patagonian sponge Cliona chilensis. J. Nat. Prod. 1998;61(4):488-490.http://dx.doi.org/10.1021/np9701945
