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Abstract:

From the leaves of Salpichroa origanifolia three new withanolides, (20S,22R,24S,25S,26R)-5α,6α:22,26:24,25-triepoxy-15,26-dihydroxy- 17(13→18)-abeo-ergosta-2,13,15,17-tetraen-1-one (salpichrolide G, 1), (20S,22R,24S,25R)-5α,6α:22,26-diepoxy-24,25,26-trihydroxy-17(13→18)-abeo- ergosta-2,13,15,17-tetraen-1-one (salpichrolide H, 2), and (20S,22R,25S)- 5α,6α:22,26-diepoxy-25,26-dihydroxy-17(13→18)-abeo-ergosta-2,13,15,17,23- pentaen-1-one (salpichrolide I, 3), were isolated and characterized by spectroscopic methods and with the aid of molecular modeling. The latter two compounds were obtained as an epimeric mixture at C-26.

Registro:

Documento: Artículo
Título:New hydroxylated withanolides from Salpichroa origanifolia
Autor:Tettamanzi, M.C.; Veleiro, A.S.; Oberti, J.C.; Burton, G.
Filiación:Depto. de Quim. Orgánica, Pabellón 2, Ciudad Universitaria, 1428 Buenos Aires, Argentina
Depto. de Quim. Orgánica, Facultad de Ciencias Químicas, Univ. Nacional de Córdoba, Ap. Postal 4, Casilla 61, 5000 Córdoba, Argentina
Palabras clave:salpichrolide g; salpichrolide h; salpichrolide i; unclassified drug; withanolide; article; carbon nuclear magnetic resonance; chemical structure; hydroxylation; molecular model; nuclear Overhauser effect; plant leaf; proton nuclear magnetic resonance; spectroscopy; stereochemistry; Salpichroa origanifolia
Año:1998
Volumen:61
Número:3
Página de inicio:338
Página de fin:342
DOI: http://dx.doi.org/10.1021/np970387s
Título revista:Journal of Natural Products
Título revista abreviado:J. Nat. Prod.
ISSN:01633864
CODEN:JNPRD
CAS:withanolide, 40326-62-3
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01633864_v61_n3_p338_Tettamanzi

Referencias:

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  • note; note; note

Citas:

---------- APA ----------
Tettamanzi, M.C., Veleiro, A.S., Oberti, J.C. & Burton, G. (1998) . New hydroxylated withanolides from Salpichroa origanifolia. Journal of Natural Products, 61(3), 338-342.
http://dx.doi.org/10.1021/np970387s
---------- CHICAGO ----------
Tettamanzi, M.C., Veleiro, A.S., Oberti, J.C., Burton, G. "New hydroxylated withanolides from Salpichroa origanifolia" . Journal of Natural Products 61, no. 3 (1998) : 338-342.
http://dx.doi.org/10.1021/np970387s
---------- MLA ----------
Tettamanzi, M.C., Veleiro, A.S., Oberti, J.C., Burton, G. "New hydroxylated withanolides from Salpichroa origanifolia" . Journal of Natural Products, vol. 61, no. 3, 1998, pp. 338-342.
http://dx.doi.org/10.1021/np970387s
---------- VANCOUVER ----------
Tettamanzi, M.C., Veleiro, A.S., Oberti, J.C., Burton, G. New hydroxylated withanolides from Salpichroa origanifolia. J. Nat. Prod. 1998;61(3):338-342.
http://dx.doi.org/10.1021/np970387s