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Abstract:

On sudden presentation of a passing shadow, the crab Chasmagnathus granulatus reacts with an escape response that habituates after repeating the same stimulus. In a first series of experiments, a range of naloxone (NX) doses (0.8, 2.4, 3.2, and 6.2 μg/g) was injected into crabs 15 min before one 15-trial habituation session. An enhancing effect of 3.2 μg NX/g on responsiveness appeared over trials, that cannot be explained either by a ceiling effect or by a delay in peak drug action. Two doses below 3.2 μg/g and one dose above had no significant effect. Results from a second series of experiments showed that the 3.2 μg NX/g effect vanishes after 15 trials (1 h after injection). The hypothesis that crab's habitution involves the action of an endogenous opioid mechanism is put forward to account for the naloxone pretreatment effect. © 1978 Academic Press, Inc.

Registro:

Documento: Artículo
Título:Effect of naloxone pretreatment on habituation in the crab chasmagnathus granulatus
Autor:Romano, A.; Lozada, M.; Maldonado, H.
Filiación:Laboratorio de Fisiologia del Comportamiento Animal, Facultad de Ciencias Exactas y Naturales, UBA, Avda Indalecio Chenaut 1910, 1426 Buenos Aires, Argentina
Palabras clave:naloxone; amphibia; animal experiment; arthropod; article; behavior; conditioning; crab; habituation; nonhuman; psychological aspect; Animal; Arousal; Brachyura; Dose-Response Relationship, Drug; Fear; Habituation (Psychophysiology); Male; Naloxone; Receptors, Opioid; Support, Non-U.S. Gov't
Año:1990
Volumen:53
Número:1
Página de inicio:113
Página de fin:122
DOI: http://dx.doi.org/10.1016/0163-1047(90)90882-7
Título revista:Behavioral and Neural Biology
Título revista abreviado:Behav. Neural Biol.
ISSN:01631047
CODEN:BNBID
CAS:naloxone, 357-08-4, 465-65-6; Naloxone, 465-65-6; Receptors, Opioid
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01631047_v53_n1_p113_Romano

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Citas:

---------- APA ----------
Romano, A., Lozada, M. & Maldonado, H. (1990) . Effect of naloxone pretreatment on habituation in the crab chasmagnathus granulatus. Behavioral and Neural Biology, 53(1), 113-122.
http://dx.doi.org/10.1016/0163-1047(90)90882-7
---------- CHICAGO ----------
Romano, A., Lozada, M., Maldonado, H. "Effect of naloxone pretreatment on habituation in the crab chasmagnathus granulatus" . Behavioral and Neural Biology 53, no. 1 (1990) : 113-122.
http://dx.doi.org/10.1016/0163-1047(90)90882-7
---------- MLA ----------
Romano, A., Lozada, M., Maldonado, H. "Effect of naloxone pretreatment on habituation in the crab chasmagnathus granulatus" . Behavioral and Neural Biology, vol. 53, no. 1, 1990, pp. 113-122.
http://dx.doi.org/10.1016/0163-1047(90)90882-7
---------- VANCOUVER ----------
Romano, A., Lozada, M., Maldonado, H. Effect of naloxone pretreatment on habituation in the crab chasmagnathus granulatus. Behav. Neural Biol. 1990;53(1):113-122.
http://dx.doi.org/10.1016/0163-1047(90)90882-7