Abstract:
E. coli BL21 synthesized purine nucleosides from pyrimidine ones. A 94% yield of adenosine from uridine was reached within 1 h.
Registro:
Documento: |
Artículo
|
Título: | An improved microbial synthesis of purine nucleosides |
Autor: | Lewkowicz, E.S.; Martínez, N.; Rogert, M.C.; Porro, S.; Iribarren, A.M. |
Filiación: | Universidad Nacional de Quilmes, R. S. Peña 180, (1876) Bernal, Buenos Aires, Argentina INGEBI, CONICET, Vuelta de Obligado 2490, (1428) Buenos Aires, Argentina
|
Palabras clave: | Biotransformations; Escherichia coli; Nucleoside phosphorylases; Purine nucleosides; nucleoside derivative; antineoplastic activity; antiviral activity; article; biotransformation; Escherichia coli; nonhuman; purine synthesis; Escherichia coli; Negibacteria |
Año: | 2000
|
Volumen: | 22
|
Número: | 16
|
Página de inicio: | 1277
|
Página de fin: | 1280
|
DOI: |
http://dx.doi.org/10.1023/A:1005689116502 |
Título revista: | Biotechnology Letters
|
Título revista abreviado: | Biotechnol. Lett.
|
ISSN: | 01415492
|
CODEN: | BILED
|
Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01415492_v22_n16_p1277_Lewkowicz |
Referencias:
- Agrawal, S., Iyer, R.P., Modified oligonucleotides as therapeutic and diagnostic agents (1995) Curr. Opin. Biotech., 6, pp. 12-19
- Hanrahan, J., Hutchinson, D., The enzymatic synthesis of antiviral agents (1992) J. Biotechnol., 23, pp. 193-210
- Iribarren, A.M., Sproat, B.S., Neuner, P., Sulston, I., Ryder, U., Lamond, A.I., 2'-O-alkyl oligoribonucleotides as antisense probes (1990) Proc. Natl. Acad. Sci. USA, 87, pp. 7747-7751
- Krenitzky, T., Koszalka, G., Purine nucleoside synthesis, an efficient method employing nucleoside phosphorylases (1981) Biochemistry, 20, pp. 3615-3621
- Krenitsky, T., Koszalka, G., Tuttle, J., Rideout, J., Elion, G., An enzymatic synthesis of purine D-arabinonucleosides (1981) Carbohydrate Res., 97, pp. 139-146
- Ling, F., Inoue, Y., Kimura, A., Purification and characterization of a novel nucleoside phosphorylase from a Klebsiella sp. and its use in the enzymatic production of adenine arabinoside (1990) Appl. Environ. Microbiol., 56, pp. 3830-3834
- Murakami, K., Shirasaka, T., Yoshioka, H., Kojima, E., Aoki, S., Ford, H., Driscoll, J., Mitsuya, H., Escherichia coli mediated biosynthesis and in vitro anti-HIV activity of lipophilic 6-halo-2',3'-dideoxypurine nucleosides (1991) J. Med. Chem., 34, pp. 1606-1612
- Pal, S., Nair, V., Enzymatic synthesis of thymidine using bacterial whole cells and isolated purine nucleoside phosphorylase (1997) Biotechnol. Lett., 19, pp. 147-158
- Perigaud, C., Gosselin, G., Imbach, J.L., Nucleosides analogues as chemoterapeutic agents: A review (1992) Nucleosides Nucleotides, 11, pp. 903-945
- Utagawa, T., Enzymatic preparation of nucleoside antibiotics (1999) J. Mol. Catal. B: Enzymatic, 6, pp. 215-222
- Utagawa, T., Morisawa, H., Yoshinaga, F., Yamazaki, A., Mitsugi, K., Hirose, Y., Microbiological synthesis of adenine arabinoside (1985) Agric. Biol. Chem., 49, pp. 1053-1058
- Yokozeki, K., Shirae, H., Kobayashi, K., Shiragami, H., Irie, Y., (1990), Method of Producing 2',3'-dideoxyinosine. US Patent No. 4,970,148
Citas:
---------- APA ----------
Lewkowicz, E.S., Martínez, N., Rogert, M.C., Porro, S. & Iribarren, A.M.
(2000)
. An improved microbial synthesis of purine nucleosides. Biotechnology Letters, 22(16), 1277-1280.
http://dx.doi.org/10.1023/A:1005689116502---------- CHICAGO ----------
Lewkowicz, E.S., Martínez, N., Rogert, M.C., Porro, S., Iribarren, A.M.
"An improved microbial synthesis of purine nucleosides"
. Biotechnology Letters 22, no. 16
(2000) : 1277-1280.
http://dx.doi.org/10.1023/A:1005689116502---------- MLA ----------
Lewkowicz, E.S., Martínez, N., Rogert, M.C., Porro, S., Iribarren, A.M.
"An improved microbial synthesis of purine nucleosides"
. Biotechnology Letters, vol. 22, no. 16, 2000, pp. 1277-1280.
http://dx.doi.org/10.1023/A:1005689116502---------- VANCOUVER ----------
Lewkowicz, E.S., Martínez, N., Rogert, M.C., Porro, S., Iribarren, A.M. An improved microbial synthesis of purine nucleosides. Biotechnol. Lett. 2000;22(16):1277-1280.
http://dx.doi.org/10.1023/A:1005689116502