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Abstract:

The present study provides information regarding the effects of the sow follicular fluid (FF) on the motility of isolated segments of swine and rabbit oviducts. In addition, the concentration of prostaglandins (PGs) F2 α, E2 and E1 in the follicular fluid of sow ovaries isolated at different stages of the sex cycle as well as the generation of the same PGs by walls of ovarian follicles in early and late proestrus, in estrus, in metestrus and in diestrus, were explored. The stimulatory contractile effect of proestrous FF in isolated segments of sow fimbria was antagonized by polyphloretin phosphate (PPP), a PG receptor blocker and by indomethacin, an inhibitor of PG synthesis. The positive inotropism evoked by the FF was mimiked by bradykinin and the influences of both interventions were similarly antagonized by PPP. It appears plausible that the inotropic effect of the preovulatory FF on the sow fimbria could be not only by PGs already present in the fluid, but also by the stimulation of the synthesis of tubal PGs by follicular fluid bradykinin. The FF also stimulated the ampullary tubal segments isolated from proestrous sows whereas the same volume of FF depressed significantly the isometric developed tension of rabbit ampulla. The total concentration of the three PGs in the FF from late proestrous follicles was significantly greater than that of the same PGs in the other two stages of the sex cycle (early proestrus and diestrus), whereas the concentration of each PG (PGE2, PGF2 α or PGE1), did not differ within any of the stages of the cycle. Furthermore, the total amount of the three PGs produced by the walls of follicles from late proestrous ovaries was also significantly greater than that generated by ovarian follicles from early proestrus, estrus, metestrus and diestrus. © 1985.

Registro:

Documento: Artículo
Título:Sow (Sus scrofa) follicular fluid: Prostaglandin content and effect on the motility of isolated oviducts
Autor:Gimeno, M.F.; Franchi, A.M.; Sterin-Speziale, N.B.; Gonzalez, E.T.; Speziale, E.H.; Gimeno, A.L.
Filiación:Centro de Estudios Farmacológicos y de Principios Naturales (CEFAPRIN), Serrano 665/669, 1414 Buenos Aires, Argentina
Consejo Nacional de Investigaciones Cientificas y Tecnicas de la Republica Argentina (CONICET). Serr, 1414 Buenos Aires, Argentina
Palabras clave:prostaglandin; animal experiment; female genital system; follicle fluid; nonhuman; priority journal; swine; uterine tube; Animals; Bradykinin; Estrus; Fallopian Tubes; Female; Indomethacin; Muscle Contraction; Ovarian Follicle; Ovum Transport; Polyphloretin Phosphate; Pregnancy; Proestrus; Prostaglandins; Prostaglandins E; Prostaglandins F; Rabbits; Swine
Año:1985
Volumen:29
Número:5
Página de inicio:831
Página de fin:846
DOI: http://dx.doi.org/10.1016/0090-6980(85)90141-8
Título revista:Prostaglandins
Título revista abreviado:Prostaglandins
ISSN:00906980
CODEN:PRGLB
CAS:Bradykinin, 58-82-2; Indomethacin, 53-86-1; Polyphloretin Phosphate, 9014-72-6; Prostaglandins; Prostaglandins E; Prostaglandins F
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00906980_v29_n5_p831_Gimeno

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Citas:

---------- APA ----------
Gimeno, M.F., Franchi, A.M., Sterin-Speziale, N.B., Gonzalez, E.T., Speziale, E.H. & Gimeno, A.L. (1985) . Sow (Sus scrofa) follicular fluid: Prostaglandin content and effect on the motility of isolated oviducts. Prostaglandins, 29(5), 831-846.
http://dx.doi.org/10.1016/0090-6980(85)90141-8
---------- CHICAGO ----------
Gimeno, M.F., Franchi, A.M., Sterin-Speziale, N.B., Gonzalez, E.T., Speziale, E.H., Gimeno, A.L. "Sow (Sus scrofa) follicular fluid: Prostaglandin content and effect on the motility of isolated oviducts" . Prostaglandins 29, no. 5 (1985) : 831-846.
http://dx.doi.org/10.1016/0090-6980(85)90141-8
---------- MLA ----------
Gimeno, M.F., Franchi, A.M., Sterin-Speziale, N.B., Gonzalez, E.T., Speziale, E.H., Gimeno, A.L. "Sow (Sus scrofa) follicular fluid: Prostaglandin content and effect on the motility of isolated oviducts" . Prostaglandins, vol. 29, no. 5, 1985, pp. 831-846.
http://dx.doi.org/10.1016/0090-6980(85)90141-8
---------- VANCOUVER ----------
Gimeno, M.F., Franchi, A.M., Sterin-Speziale, N.B., Gonzalez, E.T., Speziale, E.H., Gimeno, A.L. Sow (Sus scrofa) follicular fluid: Prostaglandin content and effect on the motility of isolated oviducts. Prostaglandins. 1985;29(5):831-846.
http://dx.doi.org/10.1016/0090-6980(85)90141-8