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Abstract:

Measurements were made of spontaneous contractions and release of prostaglandin E-and F-like material into the bathing medium by uterine horns isolated from rats in different stages of the sex cycle. After 70 min of contractile activity the preparations from estrous rats released more PGF than those from proestrous or metestrous rats. On the other hand, similar amounts of PGF-like material is generated by estrous and diestrous horns. Less PGE-like material was found in the bathing solution during estrus than in metestrus or diestrus; the values obtained during proestrus were similar to those in estrus. PGI2_like material produced by chopped uterine tissue was greater during diestrus than in estrus. The initial isometric developed tension (IDT) and tension constancy varied depeding of the stage of the sex cycle. Uteri from metestrous rats exhibited greater IDT and less % change with time than preparations from estrous or proestrous rats. The initial IDT, the tension change with time and contractile frequency correlate with the PGE-like material in the bathing solution during the 4 days of the sex cycle. There was no correlation with PGF-like material. © 1979.

Registro:

Documento: Artículo
Título:Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle
Autor:Franchi, A.M.; Chaud, M.; Borda, E.S.; Gimeno, M.F.; Lazzari, M.A.; Gimeno, A.L.
Filiación:Centro de Estudios Farmocológicos y de Principios Naturales (CEFAPRIN), V. de Obligado 2490, 1428 Buenos Aires, Argentina
Instituto de Investigaciones Hematológicas, Argentina
Palabras clave:prostaglandin; prostaglandin e; prostaglandin f; animal experiment; estrus; female genital system; myometrium; rat; uterus horn; Animals; Epoprostenol; Estrus; Female; Pregnancy; Prostaglandins; Prostaglandins E; Prostaglandins F; Rats; Rats, Inbred Strains; Uterine Contraction; Uterus; Animalia
Año:1981
Volumen:22
Número:4
Página de inicio:637
Página de fin:649
DOI: http://dx.doi.org/10.1016/0090-6980(81)90073-3
Título revista:Prostaglandins
Título revista abreviado:Prostaglandins
ISSN:00906980
CODEN:PRGLB
CAS:prostaglandin E, 11042-70-9; Epoprostenol, 35121-78-9; Prostaglandins; Prostaglandins E; Prostaglandins F
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00906980_v22_n4_p637_Franchi

Referencias:

  • Sharma, Garg, Measurement of prostaglandins E and F in the uterine tissue and uterine fluid of ovariectomized rats treated with various doses of oestradiol-17 (1977) J. Reprod. Fert., 51, pp. 119-121
  • Van Orden, Goodale, Baker, Barley, Bhatnager, Uterine Catecholamines and Prostaglandinis during the Estrous Cycle of the Rat (1980) Endocrinol., 106, pp. 1650-1654
  • Poyser, Scott, Prostaglandin and thromboxane production by the rat uterus and ovary in vitro during the oestrous cycle (1980) J. Reprod. Fert., 60, pp. 33-40
  • Ham, Cirillo, Zanetti, Kuehl, Estrogen-directed synthesis of specific prostaglandins in uterus (1975) Proc. Natn. Acad. Sci. USA, 72, pp. 1420-1429
  • Downing, Williams, Differential prostaglandin production by microsomal fractions fo rat pregnant uterus (1977) Brit. J. Pharmacol., 61, p. 158p
  • Saksena, Shaikh, Shaikh, Uterine and peripheral plasma F-prostaglandins correlated with peripheral progesterone in cyclic rats (1973) Prostaglandins, 4, pp. 243-249
  • Vane, Williams, The contribution of prostaglandin production to contractions of the isolated uterus of the rat (1973) Brit. J. Pharmacol., 48, pp. 629-639
  • Harney, Sneddon, Williams, The influence of ovarian hormones upon the motility and prostaglandin production of the pregnant rat uterus in vitro (1974) J. Endocrinol., 60, pp. 343-351
  • Dubin, Ghodgaonkar, King, Role of Prostaglandin Production in Spontaneous and Oxytocin-Induced Uterine Contractile Activity in, “in vitro” Pregnant rat Uteri (1979) Endocrinology, 105, p. 47
  • Gimeno, Sterin-Speziale, Landa, Bonacossa, Gimeno, Is the spontaneous motility of isolated rat uterus controlled by Prostaglandin E? (1979) Prostaglandinss, 17, pp. 673-683
  • Sterin-Speziale, Gimeno, Bonacossa, Gimeno, The effect of estradiol on isolated rat uterine motility and on prostaglandin generation (1980) Prostaglandins, 20, pp. 233-243
  • Gimeno, Borda, Sterin-Borda, Vidal, Gimeno, Pharmacologic influences on human ovarian contractions (1976) Obstet. Gynec. (N.Y.), 47, pp. 218-222
  • Vane, The use of isolated organs for detection active substance in the circulatory blood (1964) Brit. J. Pharmacol. Chemother., 23, pp. 360-367
  • Gilmore, Vane, Willie, Prostaglandins released by the spleen (1968) Nature, 218, pp. 135-137
  • Gimeno, Borda, Lazzari, Gimeno, Ovarian hormones inhibit the release of prostacyclin like material from isolated rat uterus (1980) Prostaglandins, 20, pp. 223-232

Citas:

---------- APA ----------
Franchi, A.M., Chaud, M., Borda, E.S., Gimeno, M.F., Lazzari, M.A. & Gimeno, A.L. (1981) . Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle. Prostaglandins, 22(4), 637-649.
http://dx.doi.org/10.1016/0090-6980(81)90073-3
---------- CHICAGO ----------
Franchi, A.M., Chaud, M., Borda, E.S., Gimeno, M.F., Lazzari, M.A., Gimeno, A.L. "Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle" . Prostaglandins 22, no. 4 (1981) : 637-649.
http://dx.doi.org/10.1016/0090-6980(81)90073-3
---------- MLA ----------
Franchi, A.M., Chaud, M., Borda, E.S., Gimeno, M.F., Lazzari, M.A., Gimeno, A.L. "Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle" . Prostaglandins, vol. 22, no. 4, 1981, pp. 637-649.
http://dx.doi.org/10.1016/0090-6980(81)90073-3
---------- VANCOUVER ----------
Franchi, A.M., Chaud, M., Borda, E.S., Gimeno, M.F., Lazzari, M.A., Gimeno, A.L. Spontaneous motility and prostaglandin generation in rat uterine horns isolated during the estrous cycle. Prostaglandins. 1981;22(4):637-649.
http://dx.doi.org/10.1016/0090-6980(81)90073-3