The use of sugar for the treatment of infected wounds was investigated in in vitro experiments with bacteria pathogenic to humans, such as Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Staphylococcus aureus. Studies showed that solutions of appropriate sugar concentration incubated at pH 7.0 and 35°C were lethal to the bacterial species studied. On the basis of these results, it is proposed that an important function of sugar in the treatment of infected wounds is to create an environment of low water activity (a(w)), which inhibits or stresses bacterial growth.
Documento: | Artículo |
Título: | In vitro study of bacterial growth inhibition in concentrated sugar solutions: microbiological basis for the use of sugar in treating infected wounds |
Autor: | Chirife, J.; Herszage, L.; Joseph, A.; Kohn, E.S. |
Filiación: | Dep. Ind., Fac. Cienc. Exactas Nat., Univ. Buenos Aires, 1428 Buenos Aires, Argentina |
Palabras clave: | disinfectant agent; sucrose; bacterium; drug sensitivity; Escherichia coli; in vitro study; injury; Klebsiella pneumoniae; nonhuman; Pseudomonas aeruginosa; Staphylococcus aureus; therapy; wound; wound infection |
Año: | 1983 |
Volumen: | 23 |
Número: | 5 |
Página de inicio: | 766 |
Página de fin: | 773 |
DOI: | http://dx.doi.org/10.1128/AAC.23.5.766 |
Título revista: | Antimicrobial Agents and Chemotherapy |
Título revista abreviado: | ANTIMICROB. AGENTS CHEMOTHER. |
ISSN: | 00664804 |
CODEN: | AMACC |
CAS: | sucrose, 122880-25-5, 57-50-1 |
Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00664804_v23_n5_p766_Chirife |