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Abstract:

The use of sugar for the treatment of infected wounds was investigated in in vitro experiments with bacteria pathogenic to humans, such as Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Staphylococcus aureus. Studies showed that solutions of appropriate sugar concentration incubated at pH 7.0 and 35°C were lethal to the bacterial species studied. On the basis of these results, it is proposed that an important function of sugar in the treatment of infected wounds is to create an environment of low water activity (a(w)), which inhibits or stresses bacterial growth.

Registro:

Documento: Artículo
Título:In vitro study of bacterial growth inhibition in concentrated sugar solutions: microbiological basis for the use of sugar in treating infected wounds
Autor:Chirife, J.; Herszage, L.; Joseph, A.; Kohn, E.S.
Filiación:Dep. Ind., Fac. Cienc. Exactas Nat., Univ. Buenos Aires, 1428 Buenos Aires, Argentina
Palabras clave:disinfectant agent; sucrose; bacterium; drug sensitivity; Escherichia coli; in vitro study; injury; Klebsiella pneumoniae; nonhuman; Pseudomonas aeruginosa; Staphylococcus aureus; therapy; wound; wound infection
Año:1983
Volumen:23
Número:5
Página de inicio:766
Página de fin:773
DOI: http://dx.doi.org/10.1128/AAC.23.5.766
Título revista:Antimicrobial Agents and Chemotherapy
Título revista abreviado:ANTIMICROB. AGENTS CHEMOTHER.
ISSN:00664804
CODEN:AMACC
CAS:sucrose, 122880-25-5, 57-50-1
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00664804_v23_n5_p766_Chirife

Citas:

---------- APA ----------
Chirife, J., Herszage, L., Joseph, A. & Kohn, E.S. (1983) . In vitro study of bacterial growth inhibition in concentrated sugar solutions: microbiological basis for the use of sugar in treating infected wounds. Antimicrobial Agents and Chemotherapy, 23(5), 766-773.
http://dx.doi.org/10.1128/AAC.23.5.766
---------- CHICAGO ----------
Chirife, J., Herszage, L., Joseph, A., Kohn, E.S. "In vitro study of bacterial growth inhibition in concentrated sugar solutions: microbiological basis for the use of sugar in treating infected wounds" . Antimicrobial Agents and Chemotherapy 23, no. 5 (1983) : 766-773.
http://dx.doi.org/10.1128/AAC.23.5.766
---------- MLA ----------
Chirife, J., Herszage, L., Joseph, A., Kohn, E.S. "In vitro study of bacterial growth inhibition in concentrated sugar solutions: microbiological basis for the use of sugar in treating infected wounds" . Antimicrobial Agents and Chemotherapy, vol. 23, no. 5, 1983, pp. 766-773.
http://dx.doi.org/10.1128/AAC.23.5.766
---------- VANCOUVER ----------
Chirife, J., Herszage, L., Joseph, A., Kohn, E.S. In vitro study of bacterial growth inhibition in concentrated sugar solutions: microbiological basis for the use of sugar in treating infected wounds. ANTIMICROB. AGENTS CHEMOTHER. 1983;23(5):766-773.
http://dx.doi.org/10.1128/AAC.23.5.766