Abstract:
This paper reviews the experimental data supporting the hypothesis that microtubulea are involved in melatonin action. Melatonin added in vitro in mM concentrations or greater impairs some but not all microtubule-dependent processes tested. In addition melatonin treatment or induction of endogenous melatonin release affect tubulin levels in the hypothalamus. Whether all these phenomena are mediated through a common mechanism remains unsettled. © 1981.
Registro:
Documento: |
Artículo
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Título: | Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action" |
Autor: | Cardinali, D.P. |
Filiación: | Centro de Estudios Farmacológicos y de Principles Naturales (CEFAPRIN), Obligado 2490, 1428 Buenos Aires, Argentina
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Palabras clave: | axonal transport; Melatonin; microtubules; mitosis; secretory process; tubulin |
Año: | 1981
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Volumen: | 29
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Número: | C
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Página de inicio: | 247
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Página de fin: | 256
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Título revista: | Advances in the Biosciences
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ISSN: | 00653446
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00653446_v29_nC_p247_Cardinali |
Citas:
---------- APA ----------
(1981)
. Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action". Advances in the Biosciences, 29(C), 247-256.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00653446_v29_nC_p247_Cardinali [ ]
---------- CHICAGO ----------
Cardinali, D.P.
"Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action""
. Advances in the Biosciences 29, no. C
(1981) : 247-256.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00653446_v29_nC_p247_Cardinali [ ]
---------- MLA ----------
Cardinali, D.P.
"Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action""
. Advances in the Biosciences, vol. 29, no. C, 1981, pp. 247-256.
Recuperado de https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00653446_v29_nC_p247_Cardinali [ ]
---------- VANCOUVER ----------
Cardinali, D.P. Molecular biology of melatonin: Assessment of the "microtubule hypothesis of melatonin action". 1981;29(C):247-256.
Available from: https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00653446_v29_nC_p247_Cardinali [ ]