Artículo

López, N.I.; Pettinari, M.J.; Nikel, P.I.; Méndez, B.S.; Gadd G.M.; Sariaslani S. "Polyhydroxyalkanoates: Much More than Biodegradable Plastics" (2015) Advances in Applied Microbiology, 2015. 93:73-106
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Abstract:

Bacterial polyhydroxyalkanoates (PHAs) are isotactic polymers that play a critical role in central metabolism, as they act as dynamic reservoirs of carbon and reducing equivalents. These polymers have a number of technical applications since they exhibit thermoplastic and elastomeric properties, making them attractive as a replacement of oil-derived materials. PHAs are accumulated under conditions of nutritional imbalance (usually an excess of carbon source with respect to a limiting nutrient, such as nitrogen or phosphorus). The cycle of PHA synthesis and degradation has been recognized as an important physiological feature when these biochemical pathways were originally described, yet its role in bacterial processes as diverse as global regulation and cell survival is just starting to be appreciated in full. In the present revision, the complex regulation of PHA synthesis and degradation at the transcriptional, translational, and metabolic levels are explored by analyzing examples in natural producer bacteria, such as Pseudomonas species, as well as in recombinant Escherichia coli strains. The ecological role of PHAs, together with the interrelations with other polymers and extracellular substances, is also discussed, along with their importance in cell survival, resistance to several types of environmental stress, and planktonic-versus-biofilm lifestyle. Finally, bioremediation and plant growth promotion are presented as examples of environmental applications in which PHA accumulation has successfully been exploited. © 2015 Elsevier Inc..

Registro:

Documento: Artículo
Título:Polyhydroxyalkanoates: Much More than Biodegradable Plastics
Autor:López, N.I.; Pettinari, M.J.; Nikel, P.I.; Méndez, B.S.; Gadd G.M.; Sariaslani S.
Filiación:Departamento de Química Biológica, Instituto de Química Biológica (IQUIBICEN-CONICET), Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain
Palabras clave:Bacteria; Bacterial ecology; Central metabolism; Global regulation; Polyhydroxyalkanoates; biodegradable plastic; glycogen; peptides and proteins; polyhydroxyalkanoic acid; polymer; protein gaca; protein gacs; unclassified drug; biodegradable plastic; polyhydroxyalkanoic acid; biofilm; bioremediation; catabolite repression; cold tolerance; degradation; Escherichia coli; gene; nonhuman; oxidation reduction reaction; plant growth; polyhydroxyalkanoic acid gene; Pseudomonas; signal transduction; stress; survival; synthesis; genetics; metabolism; Pseudomonas putida; Biodegradable Plastics; Biodegradation, Environmental; Escherichia coli; Polyhydroxyalkanoates; Pseudomonas putida
Año:2015
Volumen:93
Página de inicio:73
Página de fin:106
DOI: http://dx.doi.org/10.1016/bs.aambs.2015.06.001
Título revista:Advances in Applied Microbiology, 2015
Título revista abreviado:Adv. Appl. Microbiol.
ISSN:00652164
CODEN:ADAMA
CAS:glycogen, 9005-79-2; Biodegradable Plastics; Polyhydroxyalkanoates
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00652164_v93_n_p73_Lopez

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Citas:

---------- APA ----------
López, N.I., Pettinari, M.J., Nikel, P.I., Méndez, B.S., Gadd G.M. & Sariaslani S. (2015) . Polyhydroxyalkanoates: Much More than Biodegradable Plastics. Advances in Applied Microbiology, 2015, 93, 73-106.
http://dx.doi.org/10.1016/bs.aambs.2015.06.001
---------- CHICAGO ----------
López, N.I., Pettinari, M.J., Nikel, P.I., Méndez, B.S., Gadd G.M., Sariaslani S. "Polyhydroxyalkanoates: Much More than Biodegradable Plastics" . Advances in Applied Microbiology, 2015 93 (2015) : 73-106.
http://dx.doi.org/10.1016/bs.aambs.2015.06.001
---------- MLA ----------
López, N.I., Pettinari, M.J., Nikel, P.I., Méndez, B.S., Gadd G.M., Sariaslani S. "Polyhydroxyalkanoates: Much More than Biodegradable Plastics" . Advances in Applied Microbiology, 2015, vol. 93, 2015, pp. 73-106.
http://dx.doi.org/10.1016/bs.aambs.2015.06.001
---------- VANCOUVER ----------
López, N.I., Pettinari, M.J., Nikel, P.I., Méndez, B.S., Gadd G.M., Sariaslani S. Polyhydroxyalkanoates: Much More than Biodegradable Plastics. Adv. Appl. Microbiol. 2015;93:73-106.
http://dx.doi.org/10.1016/bs.aambs.2015.06.001