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Abstract:

BAS is a protein generated by aortic rings isolated from rats. Our previous results clearly established that BAS inhibits platelet aggregation and modifies vascular tone. We have now examined the effect of separated segments of thoracic aorta and the effect of sex on the release of the BAS and PGI2. We evaluated three different segments of thoracic aorta: A= aortic arch, B= the upper segment and C= the lowest segment of the thoracic aorta. We measured the release of BAS and PGI2 from them. The BAS production increased in the first segment (A) when compared with the other two (B and C), whilst PGI2 production was the same along the thoracic aorta. On the other hand female and male thoracic aorta produced the same levels of BAS and 6-keto PGF1α. © 1989.

Registro:

Documento: Artículo
Título:The influence of sex and different segments of thoracic aorta on bioactive aortic substance (BAS) and prostacyclin (PGI2) synthesis
Autor:Maugeri, N.; Bermejo, E.; Faletti, A.; Schattner, M.A.; Chaud, M.; Gimeno, M.F.; Lazzari, M.A.
Filiación:Department of Hemostasis and Thrombosis, Instituto de Investigaciones Hematologicas Mariano R. Castex. Academia Nacional de Medicina, Buenos Aires, Argentina
Centro de Estudios Farmacologicos, Principios Naturales (CEFAPRIN). Consejo Nacional de Investigaciones Cientificas y Tecnicas de la Re, Buenos Aires, Argentina
Palabras clave:biological aortic substance; prostacyclin; segment of aorta; sex; prostacyclin; thrombocyte aggregation inhibitor; animal cell; aorta arch; female; male; nonhuman; priority journal; prostaglandin synthesis; protein secretion; rat; sex; thoracic aorta; Animal; Aorta, Thoracic; Epoprostenol; Female; Human; In Vitro; Male; Platelet Aggregation Inhibitors; Proteins; Rats; Rats, Inbred Strains; Sex Factors
Año:1989
Volumen:56
Número:1
Página de inicio:19
Página de fin:27
DOI: http://dx.doi.org/10.1016/0049-3848(89)90004-2
Título revista:Thrombosis Research
Título revista abreviado:Thromb. Res.
ISSN:00493848
CODEN:THBRA
CAS:prostacyclin, 35121-78-9, 61849-14-7; Epoprostenol, 35121-78-9; Platelet Aggregation Inhibitors; Proteins
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00493848_v56_n1_p19_Maugeri

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Citas:

---------- APA ----------
Maugeri, N., Bermejo, E., Faletti, A., Schattner, M.A., Chaud, M., Gimeno, M.F. & Lazzari, M.A. (1989) . The influence of sex and different segments of thoracic aorta on bioactive aortic substance (BAS) and prostacyclin (PGI2) synthesis. Thrombosis Research, 56(1), 19-27.
http://dx.doi.org/10.1016/0049-3848(89)90004-2
---------- CHICAGO ----------
Maugeri, N., Bermejo, E., Faletti, A., Schattner, M.A., Chaud, M., Gimeno, M.F., et al. "The influence of sex and different segments of thoracic aorta on bioactive aortic substance (BAS) and prostacyclin (PGI2) synthesis" . Thrombosis Research 56, no. 1 (1989) : 19-27.
http://dx.doi.org/10.1016/0049-3848(89)90004-2
---------- MLA ----------
Maugeri, N., Bermejo, E., Faletti, A., Schattner, M.A., Chaud, M., Gimeno, M.F., et al. "The influence of sex and different segments of thoracic aorta on bioactive aortic substance (BAS) and prostacyclin (PGI2) synthesis" . Thrombosis Research, vol. 56, no. 1, 1989, pp. 19-27.
http://dx.doi.org/10.1016/0049-3848(89)90004-2
---------- VANCOUVER ----------
Maugeri, N., Bermejo, E., Faletti, A., Schattner, M.A., Chaud, M., Gimeno, M.F., et al. The influence of sex and different segments of thoracic aorta on bioactive aortic substance (BAS) and prostacyclin (PGI2) synthesis. Thromb. Res. 1989;56(1):19-27.
http://dx.doi.org/10.1016/0049-3848(89)90004-2