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Abstract:

Screening in selected but still wide populations such as women with recurrent fetal loss, placental insufficiency, pre-eclampsia, or needing oral contraception, or programmed high-risk surgery in both sexes, is still controversial. Knowledge of the prevalence of these polymorphisms in the general population is useful in order to take desicions that could considerably increase the burden to health resources, even in developed countries.

Registro:

Documento: Artículo
Título:Prevalence of Three Prothrombotic Polymorphisms: Factor V G1691A, Factor II G20210A and Methylenetetrahydrofolate Reductase (MTHFR) C 677T in Argentina
Autor:Genoud, V.; Castañon, M.; Annichino-Bizzacchi, J.; Korin, J.; Kordich, L.
Filiación:Facultad de Ciencias Exactas y Naturales, Dpto. Química Biológica, Universidad de Buenos Aires, Buenos Aires, Brazil
Hematology-Hemotherapy Center, State University of Campinas, Campinas SP, Brazil
Facultad de Ciencias Exactas y Naturales, UBA, Laboratorio de Hemostasia y Trombosis, Pabellón II, 4 Piso, Argentina
Palabras clave:Factor V Leiden; MTHFR; Prevalence; Prothrombin 20210; Thrombophilia; 5,10 methylenetetrahydrofolate reductase (FADH2); blood clotting factor 5 Leiden; DNA fragment; homocysteine; oral contraceptive agent; phospholipid antibody; protein C; protein S; prothrombin; activated protein C resistance; adult; aged; Argentina; article; blood donor; controlled study; deep vein thrombosis; DNA polymorphism; gene mutation; genetic disorder; genetic variability; heterozygosity; homozygosity; human; human tissue; lung embolism; prevalence; priority journal; risk factor; thromboembolism; thrombophilia; Adult; Aged; Brazil; Factor V; Genetic Screening; Heterozygote; Homozygote; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxidoreductases Acting on CH-NH Group Donors; Point Mutation; Polymorphism, Genetic; Prevalence; Prothrombin; Risk Factors; Thrombophilia
Año:2000
Volumen:100
Número:3
Página de inicio:127
Página de fin:131
DOI: http://dx.doi.org/10.1016/S0049-3848(00)00314-5
Título revista:Thrombosis Research
Título revista abreviado:Thromb. Res.
ISSN:00493848
CODEN:THBRA
CAS:5,10 methylenetetrahydrofolate reductase (FADH2), 9028-69-7; homocysteine, 454-28-4, 6027-13-0; protein C, 60202-16-6; prothrombin, 9001-26-7; Factor V, 9001-24-5; Methylenetetrahydrofolate Reductase (NADPH2), 1.5.1.20; Oxidoreductases Acting on CH-NH Group Donors, 1.5.-; Prothrombin, 9001-26-7
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00493848_v100_n3_p127_Genoud

Referencias:

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Citas:

---------- APA ----------
Genoud, V., Castañon, M., Annichino-Bizzacchi, J., Korin, J. & Kordich, L. (2000) . Prevalence of Three Prothrombotic Polymorphisms: Factor V G1691A, Factor II G20210A and Methylenetetrahydrofolate Reductase (MTHFR) C 677T in Argentina. Thrombosis Research, 100(3), 127-131.
http://dx.doi.org/10.1016/S0049-3848(00)00314-5
---------- CHICAGO ----------
Genoud, V., Castañon, M., Annichino-Bizzacchi, J., Korin, J., Kordich, L. "Prevalence of Three Prothrombotic Polymorphisms: Factor V G1691A, Factor II G20210A and Methylenetetrahydrofolate Reductase (MTHFR) C 677T in Argentina" . Thrombosis Research 100, no. 3 (2000) : 127-131.
http://dx.doi.org/10.1016/S0049-3848(00)00314-5
---------- MLA ----------
Genoud, V., Castañon, M., Annichino-Bizzacchi, J., Korin, J., Kordich, L. "Prevalence of Three Prothrombotic Polymorphisms: Factor V G1691A, Factor II G20210A and Methylenetetrahydrofolate Reductase (MTHFR) C 677T in Argentina" . Thrombosis Research, vol. 100, no. 3, 2000, pp. 127-131.
http://dx.doi.org/10.1016/S0049-3848(00)00314-5
---------- VANCOUVER ----------
Genoud, V., Castañon, M., Annichino-Bizzacchi, J., Korin, J., Kordich, L. Prevalence of Three Prothrombotic Polymorphisms: Factor V G1691A, Factor II G20210A and Methylenetetrahydrofolate Reductase (MTHFR) C 677T in Argentina. Thromb. Res. 2000;100(3):127-131.
http://dx.doi.org/10.1016/S0049-3848(00)00314-5