Artículo
Abstract:
The maturation of the corticotropin-releasing factor (CRF) neuronal system was evaluated by immunocytochemistry and morphometry in Bufo arenarum, during spontaneous metamorphosis and in tadpoles with inhibited thryroid function. The first appearance of CRF immunoreactive fibers was at the end of premetamorphosis (stage VIII). These fibers were found in small numbers and weakly stained in the median eminence and infundibular stalk. With the advance of larval development, CRF-like material stained intensely and tended to aggregate in the external zone of the median eminence. At climax stages, immunoreactive fibers and perikarya (weakly stained) were identified in the interpeduncular nucleus and in the dorsal infundibular nucleus. Morphometric and immunocytochemical results indicate that the maturation of the CRF neuronal system in Bufo arenarum occurs just before metamorphic climax, coinciding with high levels of thyroid and steroid hormones. We have also found that in larvae with inhibited thyroid function, the CRF neuronal system is able to develop, and that thyroid hormone could exert a negative feedback control on the synthesis of CRF.
Registro:
| Documento: | Artículo |
| Título: | Immunocytochemical distribution of corticotropin-releasing factor in the brain and hypophysis of larval Bufo arenarum; Effect of KClO4 during early development |
| Autor: | Miranda, L.A.; Dezi, R.E. |
| Filiación: | Departamento de Biologia, Facultad Ciencias Exactas Naturales, Universidad de Buenos Aires, (1428) Buenos Aires, Argentina |
| Palabras clave: | Amphibia; Brain; Corticotropin-releasing factor; Potassium perchlorate; Thyroid hormones; corticotropin releasing factor; potassium perchlorate; steroid hormone; thyroid hormone; animal cell; animal tissue; article; brain; hormone synthesis; hypophysis; immunocytochemistry; interpeduncular nucleus; larval development; median eminence; metamorphosis; morphometrics; negative feedback; nonhuman; tadpole; thyroid function; toad |
| Año: | 1997 |
| Volumen: | 29 |
| Número: | 6 |
| Página de inicio: | 643 |
| Página de fin: | 649 |
| DOI: | http://dx.doi.org/10.1016/S0040-8166(97)80040-7 |
| Título revista: | Tissue and Cell |
| Título revista abreviado: | Tissue Cell |
| ISSN: | 00408166 |
| CODEN: | TICEB |
| CAS: | corticotropin releasing factor, 9015-71-8, 178359-01-8, 79804-71-0, 86297-72-5, 86784-80-7; potassium perchlorate, 7778-74-7 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00408166_v29_n6_p643_Miranda |
Citas:
---------- APA ----------
Miranda, L.A. & Dezi, R.E. (1997) . Immunocytochemical distribution of corticotropin-releasing factor in the brain and hypophysis of larval Bufo arenarum; Effect of KClO4 during early development. Tissue and Cell, 29(6), 643-649.http://dx.doi.org/10.1016/S0040-8166(97)80040-7
---------- CHICAGO ----------
Miranda, L.A., Dezi, R.E. "Immunocytochemical distribution of corticotropin-releasing factor in the brain and hypophysis of larval Bufo arenarum; Effect of KClO4 during early development" . Tissue and Cell 29, no. 6 (1997) : 643-649.http://dx.doi.org/10.1016/S0040-8166(97)80040-7
---------- MLA ----------
Miranda, L.A., Dezi, R.E. "Immunocytochemical distribution of corticotropin-releasing factor in the brain and hypophysis of larval Bufo arenarum; Effect of KClO4 during early development" . Tissue and Cell, vol. 29, no. 6, 1997, pp. 643-649.http://dx.doi.org/10.1016/S0040-8166(97)80040-7
---------- VANCOUVER ----------
Miranda, L.A., Dezi, R.E. Immunocytochemical distribution of corticotropin-releasing factor in the brain and hypophysis of larval Bufo arenarum; Effect of KClO4 during early development. Tissue Cell. 1997;29(6):643-649.http://dx.doi.org/10.1016/S0040-8166(97)80040-7
