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Abstract:

A new triterpene glycoside, patagonicoside A (1), has been isolated from the sea cucumber Psolus patagonicus and its structure has been elucidated by 1D and 2D NMR (1H-, 13C-, 1H-1H COSY, HETCOR, COLOC and NOESY spectra), FAB-MS and chemical evidence. Compound 1 is a disulfated tetrasaccharide with a new aglycon moiety. Patagonicoside A (1) exhibits considerable antifungal activity against the pathogenic fungus Cladosporium cucumerinum. © 2001 Elsevier Science Ltd. All rights reserved.

Registro:

Documento: Artículo
Título:Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus
Autor:Murray, A.P.; Muniaín, C.; Seldes, A.M.; Maier, M.S.
Filiación:Departamento De Química Orgánica, Facultad De Ciencias Exactas Y Naturales, Ciudad Universitaria, Pabellón 2, 1428 Buenos Aires, Argentina
Departamento De Química, Universidad Nacional del Sur, Avda. Alem 1253, 8000 Bahía Blanca, Argentina
Museo Argentino De Ciencias Naturales Bernardino Rivadavia, Av. A. Gallardo 470, 1405 Buenos Aires, Argentina
Palabras clave:Antifungal activity; Glycosides; Holothuroidea; Psolus patagonicus; Triterpenes; antifungal agent; glycoside; patagonicoside a; triterpenic glycoside; unclassified drug; antifungal activity; article; carbon nuclear magnetic resonance; Cladosporium cucumerinum; controlled study; desulfurization; dose response; drug isolation; drug structure; echinoderm; mass spectrometry; nonhuman; priority journal; proton nuclear magnetic resonance
Año:2001
Volumen:57
Número:47
Página de inicio:9563
Página de fin:9568
DOI: http://dx.doi.org/10.1016/S0040-4020(01)00970-X
Título revista:Tetrahedron
Título revista abreviado:Tetrahedron
ISSN:00404020
CODEN:TETRA
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00404020_v57_n47_p9563_Murray

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Citas:

---------- APA ----------
Murray, A.P., Muniaín, C., Seldes, A.M. & Maier, M.S. (2001) . Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus. Tetrahedron, 57(47), 9563-9568.
http://dx.doi.org/10.1016/S0040-4020(01)00970-X
---------- CHICAGO ----------
Murray, A.P., Muniaín, C., Seldes, A.M., Maier, M.S. "Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus" . Tetrahedron 57, no. 47 (2001) : 9563-9568.
http://dx.doi.org/10.1016/S0040-4020(01)00970-X
---------- MLA ----------
Murray, A.P., Muniaín, C., Seldes, A.M., Maier, M.S. "Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus" . Tetrahedron, vol. 57, no. 47, 2001, pp. 9563-9568.
http://dx.doi.org/10.1016/S0040-4020(01)00970-X
---------- VANCOUVER ----------
Murray, A.P., Muniaín, C., Seldes, A.M., Maier, M.S. Patagonicoside A: A novel antifungal disulfated triterpene glycoside from the sea cucumber Psolus patagonicus. Tetrahedron. 2001;57(47):9563-9568.
http://dx.doi.org/10.1016/S0040-4020(01)00970-X