Artículo
Revelli, G.A.; Gros, E.G. "A facile synthesis of 4-(3β -methoxy-5α -androstan-17β -yl)- 3-pyrrolin-2-one" (1993) Synthetic Communications. 23(8):1111-1119
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Abstract:
The title compound was prepared in 4 steps from 3β-methoxy-21- hydroxy-5α-pregnan-20-one (1). The required intermediate (4) was obtained using lithium enolate derived from t-butyl acetate. Interesting enough, p-tosyl chloride in pyridine quantitatively converted compound 1 into the a-chloro ketone derivative (2). © 1993, Taylor & Francis Group, LLC. All rights reserved.
Registro:
| Documento: | Artículo |
| Título: | A facile synthesis of 4-(3β -methoxy-5α -androstan-17β -yl)- 3-pyrrolin-2-one |
| Autor: | Revelli, G.A.; Gros, E.G. |
| Filiación: | Departamento de Quimica Organica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pab. 2, 1428, Buenos Aires, Argentina |
| Palabras clave: | 4 (3beta methoxy 5alpha androstan 17beta yl) 3 pyrrolin 2 one; androstane derivative; unclassified drug; article; drug synthesis; nuclear magnetic resonance |
| Año: | 1993 |
| Volumen: | 23 |
| Número: | 8 |
| Página de inicio: | 1111 |
| Página de fin: | 1119 |
| DOI: | http://dx.doi.org/10.1080/00397919308018588 |
| Título revista: | Synthetic Communications |
| Título revista abreviado: | Synth. Commun. |
| ISSN: | 00397911 |
| Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00397911_v23_n8_p1111_Revelli |
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Citas:
---------- APA ----------
Revelli, G.A. & Gros, E.G. (1993) . A facile synthesis of 4-(3β -methoxy-5α -androstan-17β -yl)- 3-pyrrolin-2-one. Synthetic Communications, 23(8), 1111-1119.http://dx.doi.org/10.1080/00397919308018588
---------- CHICAGO ----------
Revelli, G.A., Gros, E.G. "A facile synthesis of 4-(3β -methoxy-5α -androstan-17β -yl)- 3-pyrrolin-2-one" . Synthetic Communications 23, no. 8 (1993) : 1111-1119.http://dx.doi.org/10.1080/00397919308018588
---------- MLA ----------
Revelli, G.A., Gros, E.G. "A facile synthesis of 4-(3β -methoxy-5α -androstan-17β -yl)- 3-pyrrolin-2-one" . Synthetic Communications, vol. 23, no. 8, 1993, pp. 1111-1119.http://dx.doi.org/10.1080/00397919308018588
---------- VANCOUVER ----------
Revelli, G.A., Gros, E.G. A facile synthesis of 4-(3β -methoxy-5α -androstan-17β -yl)- 3-pyrrolin-2-one. Synth. Commun. 1993;23(8):1111-1119.http://dx.doi.org/10.1080/00397919308018588
