Artículo

Starkstein, S.E.; Sabe, L.; Vázquez, S.; Tesón, A.; Petracca, G.; Chemerinski, E.; Di Lorenzo, G.; Leiguarda, R. "Neuropsychological, psychiatric, and cerebral blood flow findings in vascular dementia and Alzheimer's disease" (1996) Stroke. 27(3):408-414
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Abstract:

Background and Purpose: Psychiatric, neuropsychological, and cerebral blood flow differences between patients with ischemic vascular dementia (IVD) or Alzheimer's disease (AD) were examined. Methods: A consecutive series of patients who met either the criteria off the National Institute of Neurological Disorders Association for probable AD or the State of California AD Diagnostic and Treatment Centers criteria for probable IVD were included in the study. Twenty consecutive patients with IVD were matched for age, sex, and Mini-Mental State Examination scores with 40 consecutive patients with probable AD. Patients underwent a psychiatric interview, a neuropsychological assessment, and single-photon emission CT imaging with 99mTc- hexamethylpropyleneamine oxime. Results: Patients with IVD showed significantly more severe anosognosia (P<.05) and emotional lability (P<.01) than AD patients, but no significant between-group differences were found in the frequency and severity of depression. IVD patients showed significantly more severe deficits in tests of planning, sequencing (P<.05), and verbal fluency (P<.05) as well as significantly more severe cerebral blood flow deficits in the basal ganglia (P<.01) and the frontal lobes (P<.001) than AD patients. Conclusions: Patients with IVD showed a relatively more severe dysfunction of the frontal lobes as demonstrated by single-photon emission CT and expressed in specific psychiatric and neuropsychological changes that AD patients matched for age, sex, and severity of dementia.

Registro:

Documento: Artículo
Título:Neuropsychological, psychiatric, and cerebral blood flow findings in vascular dementia and Alzheimer's disease
Autor:Starkstein, S.E.; Sabe, L.; Vázquez, S.; Tesón, A.; Petracca, G.; Chemerinski, E.; Di Lorenzo, G.; Leiguarda, R.
Filiación:Department of Behavioral Neurology, Raul Carrea Inst. of Neurol. Res., Buenos Aires, Argentina
Department of Clinical Neurology, Raul Carrea Inst. of Neurol. Res., Buenos Aires, Argentina
Department of Nuclear Medicine, Raul Carrea Inst. of Neurol. Res., Buenos Aires, Argentina
Department of Neuroradiology, Raul Carrea Inst. of Neurol. Res., Buenos Aires, Argentina
Department of Behavioral Neurology, Raul Carrea Inst. of Neurol. Res., Montañeses 2325, 1428 Buenos Aires, Argentina
Palabras clave:Alzheimer's disease; cerebral blood flow; dementia; neuropsychology; aged; anosognosia; article; brain blood flow; cognitive defect; dementia; depression; disease association; female; human; major clinical study; male; neuropsychological test; neuropsychology; priority journal; rating scale; single photon emission computer tomography
Año:1996
Volumen:27
Número:3
Página de inicio:408
Página de fin:414
DOI: http://dx.doi.org/10.1161/01.STR.27.3.408
Título revista:Stroke
Título revista abreviado:STROKE
ISSN:00392499
CODEN:SJCCA
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00392499_v27_n3_p408_Starkstein

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Citas:

---------- APA ----------
Starkstein, S.E., Sabe, L., Vázquez, S., Tesón, A., Petracca, G., Chemerinski, E., Di Lorenzo, G.,..., Leiguarda, R. (1996) . Neuropsychological, psychiatric, and cerebral blood flow findings in vascular dementia and Alzheimer's disease. Stroke, 27(3), 408-414.
http://dx.doi.org/10.1161/01.STR.27.3.408
---------- CHICAGO ----------
Starkstein, S.E., Sabe, L., Vázquez, S., Tesón, A., Petracca, G., Chemerinski, E., et al. "Neuropsychological, psychiatric, and cerebral blood flow findings in vascular dementia and Alzheimer's disease" . Stroke 27, no. 3 (1996) : 408-414.
http://dx.doi.org/10.1161/01.STR.27.3.408
---------- MLA ----------
Starkstein, S.E., Sabe, L., Vázquez, S., Tesón, A., Petracca, G., Chemerinski, E., et al. "Neuropsychological, psychiatric, and cerebral blood flow findings in vascular dementia and Alzheimer's disease" . Stroke, vol. 27, no. 3, 1996, pp. 408-414.
http://dx.doi.org/10.1161/01.STR.27.3.408
---------- VANCOUVER ----------
Starkstein, S.E., Sabe, L., Vázquez, S., Tesón, A., Petracca, G., Chemerinski, E., et al. Neuropsychological, psychiatric, and cerebral blood flow findings in vascular dementia and Alzheimer's disease. STROKE. 1996;27(3):408-414.
http://dx.doi.org/10.1161/01.STR.27.3.408