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Abstract:

Synthesis of 3β,23-diacetoxy-24-nor-5-cholene in six steps from 3β,21-diacetoxy-5-pregnen-20-one has been achieved by a new approach. The method would allow to label the side chain of a bile acid at carbon-atom 21. © 1980, All rights reserved.

Registro:

Documento: Artículo
Título:A new approach to the synthesis of 3β,23-diacetoxy-24-nor-5-cholene from 3β,21-diacetoxy-5-pregnen-20-one
Autor:Seldes, A.M.; Anding, C.R.; Gros, E.G.
Filiación:Departamento de Quimica Orgánica, Facultad de Ciencias Exactas Y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pabellón 2, Buenos Aires, 1428, Argentina
Palabras clave:24 norcholest 5 ene 3beta,23 diol diacetate; 3beta,21 diacetoxypregn 5 en 20 one; bile acid; unclassified drug; article; drug synthesis
Año:1980
Volumen:36
Número:5
Página de inicio:575
Página de fin:580
DOI: http://dx.doi.org/10.1016/0039-128X(80)90079-3
Título revista:Topics in Catalysis
Título revista abreviado:Top. Catal.
ISSN:0039128x
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0039128x_v36_n5_p575_Seldes

Referencias:

  • On leave of absence from University Louis Pasteur, Strasbourg, France; Porto, A.M., Baralle, F.E., Gros, E.G., (1972) J. Steroid Biochem., 3, p. 11. , and previous papers cited therein
  • Cocker, J.D., Henbest, H.B., Phillipps, G.H., Slater, G.P., Thomas, D.A., (1965) J. Chem. Soc., 6
  • Ruzicka, L., Reichstein, T., Furst, A., Über Steroide und Sexualhormone. (66. Mitteilung). Herstellung von Lactonen vom Typus der Digitalis-Genine (1941) Helvetica Chimica Acta, 24, p. 76
  • Pettit, G.R., Herald, Ch.L., Yardley, J.P., (1970) J. Org. Chem., 35, p. 1389
  • Sondheimer, F., Mechoulan, R., (1958) J. Amer. Chem. Soc., 80, p. 3087
  • Burton, G., Gros, E.G., (1977) J. Steroid Biochem., 8, p. 69
  • Frankenfeld, J.W., Werner, J.J., (1969) J. Org. Chem., 34, p. 3689
  • Seldes, A.M., Gros, E.G., (1979) J. Steroid Biochem., 11, p. 1573

Citas:

---------- APA ----------
Seldes, A.M., Anding, C.R. & Gros, E.G. (1980) . A new approach to the synthesis of 3β,23-diacetoxy-24-nor-5-cholene from 3β,21-diacetoxy-5-pregnen-20-one. Topics in Catalysis, 36(5), 575-580.
http://dx.doi.org/10.1016/0039-128X(80)90079-3
---------- CHICAGO ----------
Seldes, A.M., Anding, C.R., Gros, E.G. "A new approach to the synthesis of 3β,23-diacetoxy-24-nor-5-cholene from 3β,21-diacetoxy-5-pregnen-20-one" . Topics in Catalysis 36, no. 5 (1980) : 575-580.
http://dx.doi.org/10.1016/0039-128X(80)90079-3
---------- MLA ----------
Seldes, A.M., Anding, C.R., Gros, E.G. "A new approach to the synthesis of 3β,23-diacetoxy-24-nor-5-cholene from 3β,21-diacetoxy-5-pregnen-20-one" . Topics in Catalysis, vol. 36, no. 5, 1980, pp. 575-580.
http://dx.doi.org/10.1016/0039-128X(80)90079-3
---------- VANCOUVER ----------
Seldes, A.M., Anding, C.R., Gros, E.G. A new approach to the synthesis of 3β,23-diacetoxy-24-nor-5-cholene from 3β,21-diacetoxy-5-pregnen-20-one. Top. Catal. 1980;36(5):575-580.
http://dx.doi.org/10.1016/0039-128X(80)90079-3