Abstract:
Seven new C-secosteroids were isolated from the gorgonian Tripalea clavaria collected from the South Atlantic. These compounds have a Δ5, 9,11-secosteroid nucleus together with a 22S hydroxyl group. The absolute configuration of the 22-hydroxyl group was determined with the help of COSY spectra of the Mosher esters of the compounds. © 2007 Elsevier Inc. All rights reserved.
Registro:
Documento: |
Artículo
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Título: | New C-secosteroids from the gorgonian Tripalea clavaria |
Autor: | Rodríguez Brasco, M.F.; Genzano, G.N.; Palermo, J.A. |
Filiación: | UMYMFOR-Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pab. 2, 1428 Buenos Aires, Argentina Laboratorio de Biología de Cnidarios (LABIC), Depto. de Ciencias Marinas, FCEN, Funes, 3250 Mar del Plata, Argentina
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Palabras clave: | Gorgonian; Marine sterols; Secosteroids; Tripalea clavaria; 3beta acetoxy 11,21,22 trihydroxy 9,11 secocholest 5 en 9 one; 3beta acetoxy 11,22 dihydroxy 9,11 secocholest 5 en 9 one; 3beta acetoxy 11,22 dihydroxy 9,11 secoergost 5,24(28) dien 9 one; 3beta,11 dihydroxy 9,11 seco 24 norcholest 5 en 9 one; 3beta,11,21,22 tetrahydroxy 9,11 secocholest 5 en 9 one; 3beta,11,22 trihydroxy 9,11 secocholest 5 en 9 one; 3beta,11,22 trihydroxy 9,11 secocholest 5,24 dien 9 one; secosteroid; unclassified drug; antibiotic sensitivity; antimicrobial activity; article; carbon nuclear magnetic resonance; coelenterate; drug isolation; drug structure; nonhuman; proton nuclear magnetic resonance; Staphylococcus aureus; Tripalea clavaria; Animals; Anthozoa; Anti-Bacterial Agents; Antibiotics, Antifungal; Bacillus subtilis; Botrytis; Candida albicans; Escherichia coli; Magnetic Resonance Spectroscopy; Molecular Structure; Secosteroids; Staphylococcus aureus; Gorgonia; Tripalea clavaria |
Año: | 2007
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Volumen: | 72
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Número: | 14
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Página de inicio: | 908
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Página de fin: | 913
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DOI: |
http://dx.doi.org/10.1016/j.steroids.2007.07.013 |
Título revista: | Steroids
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Título revista abreviado: | Steroids
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ISSN: | 0039128X
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CODEN: | STEDA
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CAS: | Anti-Bacterial Agents; Antibiotics, Antifungal; Secosteroids
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Registro: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0039128X_v72_n14_p908_RodriguezBrasco |
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Citas:
---------- APA ----------
Rodríguez Brasco, M.F., Genzano, G.N. & Palermo, J.A.
(2007)
. New C-secosteroids from the gorgonian Tripalea clavaria. Steroids, 72(14), 908-913.
http://dx.doi.org/10.1016/j.steroids.2007.07.013---------- CHICAGO ----------
Rodríguez Brasco, M.F., Genzano, G.N., Palermo, J.A.
"New C-secosteroids from the gorgonian Tripalea clavaria"
. Steroids 72, no. 14
(2007) : 908-913.
http://dx.doi.org/10.1016/j.steroids.2007.07.013---------- MLA ----------
Rodríguez Brasco, M.F., Genzano, G.N., Palermo, J.A.
"New C-secosteroids from the gorgonian Tripalea clavaria"
. Steroids, vol. 72, no. 14, 2007, pp. 908-913.
http://dx.doi.org/10.1016/j.steroids.2007.07.013---------- VANCOUVER ----------
Rodríguez Brasco, M.F., Genzano, G.N., Palermo, J.A. New C-secosteroids from the gorgonian Tripalea clavaria. Steroids. 2007;72(14):908-913.
http://dx.doi.org/10.1016/j.steroids.2007.07.013