Artículo

Maggiora, E.; Silberstein, C.; Arany, E.; Salvidea, J.C.; Castillo, E.D.; Uranga, J. "Enhanced Glomerulopressin Production and Glomerular Filtration Rate by Amino Acid Infusion in Normal Humans" (1991) Proceedings of the Society for Experimental Biology and Medicine. 196(2):170-174
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Abstract:

Amino acid infusion induces a rise in glomerular filtration rate (GFR) in normal subjects, but the mechanism is as yet unknown. Glomerulopressin infused into the renal arteries of rats and dogs increases GFR. The aim of this study was to ascertain whether amino acid infusion raised glomerulopressin production and GFR. Accordingly, before renal arteriovenography, in 11 potential kidney donors, the caval catheter was introduced into the right hepatic vein and 60-ml blood samples were collected at the beginning and end of each experiment; six patients received amino acid infusion and five a saline infusion. Glomerulopressin in ultrafiltrates from hepatic vein plasma was measured by toad bioassay and GFR determined with diethylenetriamine pentaacetic acid-Tc99. The amino acid-infused group showed significant glomerulopressin activity in ultrafiltrates, as well as a significant GFR increase, whereas in the control group no glomerulopressin activity was observed, and there was no change in GFR. These findings suggest that intravenous amino acid infusion stimulates glomerulopressin production, which may in turn induce an increase in GFR. © 1991, SAGE Publications. All rights reserved.

Registro:

Documento: Artículo
Título:Enhanced Glomerulopressin Production and Glomerular Filtration Rate by Amino Acid Infusion in Normal Humans
Autor:Maggiora, E.; Silberstein, C.; Arany, E.; Salvidea, J.C.; Castillo, E.D.; Uranga, J.
Filiación:Instituto de Biología y Medicina Experimental, Vuelta de Obligado 2490, 1428 Buenos Aires, Argentina
Nephrology Service and Radiology Service, Sanatorio Mitre, Bartolomé Mitre 2553, 1039 Buenos Aires, Argentina
Palabras clave:amino acid; glomerulopressin; unclassified drug; article; female; glomerulus filtration rate; human; human experiment; human tissue; kidney donor; male; normal human; priority journal; Adult; Amino Acids; Analysis of Variance; Female; Glomerular Filtration Rate; Glucuronates; Glucuronidase; Human; Infusions, Intravenous; Kidney Glomerulus; Male; Regional Blood Flow; Support, Non-U.S. Gov't; Anura; Canis familiaris; Glomerulus
Año:1991
Volumen:196
Número:2
Página de inicio:170
Página de fin:174
DOI: http://dx.doi.org/10.3181/00379727-196-43174
Título revista:Proceedings of the Society for Experimental Biology and Medicine
Título revista abreviado:Proc. Soc. Exp. Biol. Med.
ISSN:00379727
CAS:Amino Acids; glomerulopressin, 39372-38-8; Glucuronates; Glucuronidase, EC 3.2.1.31
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00379727_v196_n2_p170_Maggiora

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Citas:

---------- APA ----------
Maggiora, E., Silberstein, C., Arany, E., Salvidea, J.C., Castillo, E.D. & Uranga, J. (1991) . Enhanced Glomerulopressin Production and Glomerular Filtration Rate by Amino Acid Infusion in Normal Humans. Proceedings of the Society for Experimental Biology and Medicine, 196(2), 170-174.
http://dx.doi.org/10.3181/00379727-196-43174
---------- CHICAGO ----------
Maggiora, E., Silberstein, C., Arany, E., Salvidea, J.C., Castillo, E.D., Uranga, J. "Enhanced Glomerulopressin Production and Glomerular Filtration Rate by Amino Acid Infusion in Normal Humans" . Proceedings of the Society for Experimental Biology and Medicine 196, no. 2 (1991) : 170-174.
http://dx.doi.org/10.3181/00379727-196-43174
---------- MLA ----------
Maggiora, E., Silberstein, C., Arany, E., Salvidea, J.C., Castillo, E.D., Uranga, J. "Enhanced Glomerulopressin Production and Glomerular Filtration Rate by Amino Acid Infusion in Normal Humans" . Proceedings of the Society for Experimental Biology and Medicine, vol. 196, no. 2, 1991, pp. 170-174.
http://dx.doi.org/10.3181/00379727-196-43174
---------- VANCOUVER ----------
Maggiora, E., Silberstein, C., Arany, E., Salvidea, J.C., Castillo, E.D., Uranga, J. Enhanced Glomerulopressin Production and Glomerular Filtration Rate by Amino Acid Infusion in Normal Humans. Proc. Soc. Exp. Biol. Med. 1991;196(2):170-174.
http://dx.doi.org/10.3181/00379727-196-43174