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Soroldoni, D.; Jörg, D.J.; Morelli, L.G.; Richmond, D.L.; Schindelin, J.; Jul̈icher, F.; Oates, A.C. "A doppler effect in embryonic pattern formation" (2014) Science. 345(6193):222-225
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Abstract:

During embryonic development, temporal and spatial cues are coordinated to generate a segmented body axis. In sequentially segmenting animals, the rhythm of segmentation is reported to be controlled by the time scale of genetic oscillations that periodically trigger new segment formation. However, we present real-time measurements of genetic oscillations in zebrafish embryos showing that their time scale is not sufficient to explain the temporal period of segmentation. A second time scale, the rate of tissue shortening, contributes to the period of segmentation through a Doppler effect. This contribution is modulated by a gradual change in the oscillation profile across the tissue. We conclude that the rhythm of segmentation is an emergent property controlled by the time scale of genetic oscillations, the change of oscillation profile, and tissue shortening.

Registro:

Documento: Artículo
Título:A doppler effect in embryonic pattern formation
Autor:Soroldoni, D.; Jörg, D.J.; Morelli, L.G.; Richmond, D.L.; Schindelin, J.; Jul̈icher, F.; Oates, A.C.
Filiación:Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstr 108, 01307 Dresden, Germany
Medical Research Council (MRC), National Institute for Medical Research, The Ridgeway, Mill Hill, London, NW7 1AA, United Kingdom
Department of Cell and Developmental Biology, University College London, Gower Street, London, WC1E 6BT, United Kingdom
Max Planck Institute for the Physics of Complex Systems, Nöthnitzer Strasse 38, 01187 Dresden, Germany
Universidad de Buenos Aires, Instituto de Física de Buenos Aires, Consejo Nacional de Investigaciones Científicas Y Técnicas, 1428 Buenos Aires, Argentina
Laboratory for Optical and Computational Instrumentation, University of Wisconsin at Madison, 1675 Observatory Drive, Madison, WI 53706, United States
Palabras clave:cyprinid; Doppler effect; embryo; embryonic development; genetic variation; animal experiment; article; biological rhythm; Doppler flowmetry; embryo development; embryo pattern formation; embryo segmentation; embryonic structures; gene expression; genetic analysis; germ layer; kinematics; nonhuman; oscillation; physical parameters; priority journal; spike wave; steady state; tissue level; transgenics; zebra fish; animal; animal embryo; genetics; morphogenesis; periodicity; physiology; prenatal development; Animals; Body Patterning; Doppler Effect; Embryo, Nonmammalian; Periodicity; Zebrafish
Año:2014
Volumen:345
Número:6193
Página de inicio:222
Página de fin:225
DOI: http://dx.doi.org/10.1126/science.1253089
Título revista:Science
Título revista abreviado:Science
ISSN:00368075
CODEN:SCIEA
Registro:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00368075_v345_n6193_p222_Soroldoni

Referencias:

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Citas:

---------- APA ----------
Soroldoni, D., Jörg, D.J., Morelli, L.G., Richmond, D.L., Schindelin, J., Jul̈icher, F. & Oates, A.C. (2014) . A doppler effect in embryonic pattern formation. Science, 345(6193), 222-225.
http://dx.doi.org/10.1126/science.1253089
---------- CHICAGO ----------
Soroldoni, D., Jörg, D.J., Morelli, L.G., Richmond, D.L., Schindelin, J., Jul̈icher, F., et al. "A doppler effect in embryonic pattern formation" . Science 345, no. 6193 (2014) : 222-225.
http://dx.doi.org/10.1126/science.1253089
---------- MLA ----------
Soroldoni, D., Jörg, D.J., Morelli, L.G., Richmond, D.L., Schindelin, J., Jul̈icher, F., et al. "A doppler effect in embryonic pattern formation" . Science, vol. 345, no. 6193, 2014, pp. 222-225.
http://dx.doi.org/10.1126/science.1253089
---------- VANCOUVER ----------
Soroldoni, D., Jörg, D.J., Morelli, L.G., Richmond, D.L., Schindelin, J., Jul̈icher, F., et al. A doppler effect in embryonic pattern formation. Science. 2014;345(6193):222-225.
http://dx.doi.org/10.1126/science.1253089